2008, Number 2
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Med Sur 2008; 15 (2)
Refeeding syndrome in the critically ill patient
Carrillo ER, Escobar AE, Flores GLE, Lezama MJI
Language: Spanish
References: 37
Page: 93-99
PDF size: 164.13 Kb.
ABSTRACT
Refeeding syndrome is characterized by metabolic and hydroelectrolytical abnormalities in malnourished critical patients with reinstitution of nutrition. Risk factors associated to this syndrome are acelerated weight loss, chemotherapy, radiotherapy, alcoholism and malabsortion-related diseases. Clinical manifestations are attributable to hypophosphatemia and include cardiac failure, muscle weakness, and immunological, haematological, neurological and gastrointestinal disorders and finally death. Recognition for patients with potential risks for developing this syndrome and timely management is important to diminish morbi-mortality.
REFERENCES
Marinella MA. The refeeding syndrome: implications for the inpatient rehabilitation unit. Am J Phys Med Rehabil 2004; 83: 65-68.
Marinella MA. The refeeding syndrome and hypophosphatemia. Nutr Rev 2003; 61: 320-323.
Solomon SM, Kirby DF. The refeeding syndrome: A review. JPEN J Parenter Enteral Nutr 1990; 14: 90-97.
Crook MA, Hally V, Panteli JV. The importance of the refeeding syndrome. Nutrition 2001; 17: 632-637.
Marinella MA. Refeeding syndrome and hypophosphatemia. J Intens Care Medicine 2005; 20(3): 155-159.
Brooks MJ, Melnik G. The refeeding syndrome: An approach to understanding its complications and preventing its occurrence. Pharmacotherapy 1995; 15: 713-726.
Terlevich A, Hearing SD, Woltersdorf WW et al. Refeeding syndrome: Effective and safe treatment with phosphates polyfusor. Aliment Pharmacol Ther 2003; 17: 1325-1329.
Schnitker MA, Mattman PE, Bliss TL. A clinical study of malnutrition in Japanese prisoners of war. Ann Intern Med 1951; 35: 69.
Burger GCE, Drummond JC, Sandstead HR. Malnutrition and starvation in western Netherlands, September 1944-July 1945. (Parts 1 and 2). The Hague: General State Printing Office. (1948).
Schnitker MA, Mattman PE, Bliss TL. A clinical study of malnutrition in Japanese prisoners of war. Annuals of Internal Medicine 1951: 35, 69-96.
Lauts NM. Management of the patient with refeeding syndrome. J Infus Nurs 2005; 28(5): 337-42.
Ornstein RM, Golden NH, Jacobson MS, Shenker IR. Hypophosphatemia during nutritional rehabilitation in anorexia nervosa: implications for refeeding and monitoring. J Adolesc Health 2003; 32: 83-88.
O’Donnell TF, Clowes HA, Blackburn GL et al. Proteolysis association with a deficit of peripheral energy fuel substrates in septic man. Surgery 1976; 80: 192.
Allison SP. Effect of insulin on metabolic response to injury. JPEN 1980; 4: 175.
Subramanian R, Khadori R. Severe hypophosphatemia: pathophysiologic implications, clinical presentations, and treatment. Medicine (Baltimore). 2000; 79: 1-8.
Marik PE, Bedigian MK. Refeeding hypophosphatemia in critically ill patients in an intensive care unit. Arch Surg 1996; 131: 1043-1047.
Mallett M. Refeeding syndrome. Age Ageing 2002; 31: 65-66.
Weisinger JR, Bellorin-Font E. Magnesium and phosphorus. Lancet 1998; 352: 391-396.
Dwyer K, Barone JE, Rogers JF. Severe hypophosphatemia in postoperative patients. Nutr Clin Pract 1992; 7: 279-283.
Bringhurst FR, Demay MB, Krane SM, Kronenberg HM. Bone and mineral metabolism in health and disease. In: Kasper DL, Braunwald E, Fauci AS et al, eds. Harrison’s Principles of Internal Medicine. 16th ed. New York: McGraw-Hill, 2005: 2238-2249.
Shiber JR, Mattu A. Serum phosphate abnormalities in the emergency department. J Emerg Med 2002; 23: 395-400.
Klein CJ, Stanek GS, Wiles CE. Overfeeding macronutrients to critically ill adults: metabolic complications. J Am Diet Assoc 1998; 98: 795-806.
Prankerd TAJ, Altman KI. Metabolism of phosphorus in red blood cells. Biochem J 1954; 58: 622.
Kohn MR, Goleen NH, Shenker IR. Cardiac arrest and delirium: presentations of the refeeding syndrome in severely malnourished adolescents with anorexia nervosa. J Adolesc Health 1998; 22: 239-243.
Huang YL, Fang CT, Tseng MC. Lee YJ, Lee MB. Life-threatening refeeding syndrome in a severely malnourished anorexia nervosa patient. J Formos Med Assoc 2001; 100: 343-346.
Newman JH, Neff TA, Ziporin P. Acute respiratory failure associated with hypophosphataemia. N Engl J Med 1977; 296: 1101.
Bloom WL. Carbohydrate and water balance. Am J Clin Nutr 1967; 20: 157.
Wolfe RR, Allsop JR, Burke JF. Glucose metabolism in man. Response to intravenous glucose infusion. Metabolism 1979; 28: 210.
Thiebaud D, Schutz Y, Acheson K et al. Energy cost of glucose storage in human subjects during glucose-insulin infusions. Am J Physiol 1983; 244: 216.
Saito T, Tojo K, Miyashita Y, Tominaga M, Masai A, Tajima N. Acute liver damage and subsequent hypophosphatemia in malnourished patients. Case reports and review of literature. Int J Eat Disord 2007, en publicación.
Crook MA. Lipid clearance and total parenteral nutrition: the importance of monitoring plasma lipids. Nutrition 2000; 16: 774.
Reuler JB, Girard DE, Cooney TG. Wernicke’s encephalopathy. N Engl J Med 1985; 312: 1035.
Drenick EJ, Joven CB, Swendseid ME. Occurrence of acute Wernicke’s encephalopathy during prolonged starvation for the treatment of obesity. N Engl J Med 1966; 274: 937.
Btaiche IF, Khalidi N. Metabolic complications of parenteral nutrition in adults, part 1. Am J Health-Syst Pharm 2004; 61: 1938-1949.
American Medical Association Department of Foods and Nutrition Advisory Group. Multivitamin preparations for parenteral use, 1975. J Parenter Enteral Nutr. 1979; 3: 258-62.
Rossen GH, Boullata JI, O´rangers EA et al. Intravenous phosphate repletion regimen for critical ill patients with moderate hypophosphatemia. Crit Care Med 1995; 23: 1204-1210.
Hay WW Jr, Thureen PJ. Indirect calorimetry: a potential but as yet unrealized technique for guiding nutritional management. J Pediatr (Rio J) 2007; 83(6): 490-3.