Familiar adenomatous polyposis: presentation of two cases in identical male twins

David Ramírez-Tapia; Abel Jalife-Montaño; Karla Elena Domínguez-Meléndez; Armando Vargas-Domínguez; Luis Humberto Ortega-León; Alejandro Rodríguez-Báez

2008, Number 2

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Cir Cir 2008; 76 (2)

Familiar adenomatous polyposis: presentation of two cases in identical male twins

Ramírez-Tapia D, Jalife-Montaño A, Domínguez-Meléndez KE, Vargas-Domínguez A, Ortega-León LH, Rodríguez-Baez A

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Language: Spanish
References: 11
Page: 173-176
PDF size: 95.82 Kb.

ABSTRACT

Background: One hundred percent of the cases of familial adenomatous polyposis (FAP) will develop carcinoma; therefore, the necessity of an early diagnosis at an early age with immediate therapy is essential. In the presence of identical twins it is mandatory to undergo full colonic examination as quickly as possible. The study took place at a third-level General Hospital with the objective of explaining in detail the importance of the early diagnosis of FAP.
Clinical cases: We report here of two cases of familial adenomatous polyposis (FAP) in identical male twins who were operated on at different times with different outcomes and prognosis. The first twin was treated 20 years ago at an early age and underwent subtotal colectomy with ileoproctostomy. This patient is currently asymptomatic, with no evidence of malignancy.
The second twin was operated on at the age of 33 years and was already a carrier of a well-differentiated adenocarcinoma of the rectum.
Conclusion: Opportune therapy carried out on the first twin has kept him free of disease in contrast with the delay in treatment of the second twin who developed carcinoma.

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