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2008, Number 1

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Gac Med Mex 2008; 144 (1)

El incidentaloma hipofisario

Esquenazi Y, Guinto G, Mercado M

Language: Spanish
References: 56
Page: 47-53
PDF size: 106.88 Kb.


ABSTRACT

The rapid development of highly accurate imaging techniques, has led to the discovery of asymptomatic lesions within the pituitary gland that constitute a significant challenge for clinicians and neurosurgeons. These lesions found incidentally are termed incidentalomas and can be observed in approximately 10% of MRI studies performed among healthy subjects. The natural course ofthese lesions has not been clearly defined. Although some of these masses do not change in size overtime and some may even shrink spontaneously, others have the potential risk to increase in volume and cause symptoms associated with mass effect or hormonal hypersecretion. This review describes the current therapeutic and diagnostic consensus in incidentaloma management, and places special emphasis on hormonal and imaging factors suggestive of high risk tumors.


REFERENCES

  1. Copeland PM The incidentally discovered adrenal mass. Ann Intern Med 1983;98:940-945.

  2. Mirilas P, Skandalakis JE. Benign anatomical mistakes: Incidentaloma. Am Surg 2002;68:1026-8.

  3. Molitch ME, Russell EJ. The pituitary incidentaloma. Ann Intern Med 1990;112:925-931.

  4. Sanno N, Oyama K, Tahara S, Teramoto A, Kato Y. A survey of pituitary incidentalomas in Japan. Eur J Endocrinol 2003;149:123-127

  5. Nishizawa S, Ohta S, Yokohama T, Uemura K. Therapeutic strategy for incidentally found pituitary tumors (pituitary incidentalomas). Neurosurgery 1998;43:1344-1350.

  6. Donovan LE, Corenblum B. The natural history of the pituitary incidentaloma. Arch Intern Med 1995;155:181-183.

  7. King JT, Justice AC, Aron DC. Management of incidental pituitary microadenomas: A cost- effectiveness analysis. J Clin Endocrinol Metab 1997;82:3625-3632.

  8. Arita K, Tominaga A, Sugiyama K, Eguchi K, Iida K, Sumida M, et al. Natural course of incidentally found nonfunctioning pituitary adenoma, with special referente to pituitary apoplexy during follow-up examination. J Neurosurg 2006;104:884-891.

  9. Hall WA, Luciano MG, Doppman JL, Patronas NJ, Oldfield EH. Pituitary magnetic resonance imaging in normal volunteers: Occult adenomas in the general population. Ann Intern Med 1994;120:817-820.

  10. Chambers EF, Tursky PA, LeMasters D, Newton TH. Regions of low density in the contrast-enhanced pituitary gland: Normal and pathologic processes. Radiology 1982;144:109-113.

  11. Teramoto A, Hirakawa K, Sanno N, Osamura Y. Incidental pituitary lesions in 1000 unselected autopsy specimens. Radiology 1994;193:161-164.

  12. Auer RN, Alakija P, Sutherland GR. Asymptomatic large pituitary adenomas discovered at autopsy. Surg Neurol 1996;46:28-31.

  13. Fainstein Day P, Guitelman M, Artese R, Fiszledjer L, Chervin A, Vitale NM, et al. Retrospective multicentric study of pituitary incidentalomas. Pituitary 2004;7:145-148.

  14. Reincke M, Allolio B, Saeger W, Menzel J, Winkelmann W. The incidentaloma of the pituitary gland. Is Neurosurgery required? JAMA 1990;263:2772-2776.

  15. Chanson P, Young J. Pituitary incidentalomas. Endocrinologist 2003;13:124-135.

  16. Elster AD. Modern imaging of the pituitary. Radiology 1993;187:1-14

  17. Brown SB, Irwin KM, Enzmann DR. CT characteristics of the normal pituitary gland. Neuroradiology 1983;24:259-262.

  18. Sheppard MC, Stewart PM. Imaging the pituitary. En: Pituitary Disease. Norwell Massachusetts, EUA: Kluwer Academic; 2002. pp. 207-215.

  19. Bilaniuk LT, Zimmerman RA, Wehrli FW, Snyder PJ, Goldberg HI, Grossman RI, et al. Magnetic resonance imaging of pituitary lesions using 1.0 to 1.5 T field strength. Radiology 1984;153:415-418.

  20. Zee CS, Go JL, Kim PE, Mitchell D, Ahmadi J. Imaging of the pituitary and parasellar region; Neurosurg Clin N Am 2003;14:55-80.

  21. Sam S, Molitch ME. The pituitary mass: Diagnosis and management. Rev in Endocr Metab Disord 2005;6:55-62.

  22. Chanson P, Daujat F, Young J, Bellucci A, Kujas M, Doyon D, et al. Normal pituitary hypertrophy as a frequent cause of pituitary incidentaloma: A followup study. J Clin Endocrinol Metab 2001;86:3009-3015.

  23. Foyouzi N, Frisbaek Y, Norwitz ER. Pituitary gland and pregnancy. Obstet Gynecol Clin North Am 2004;31:873-892.

  24. Feldkamp J, Santen R, Harms E, Aulich A, Moddeer U, Scherbaum WA. Incidentally discovered pituitary lesions: high frequency of macroadenomas and hormone-secreting adenomas-results of a prospective study. Clinical Endocrinol 1999;51:109-113.

  25. Oyama K, Sanno N, Tahara S, Teramoto A. Management of pituitary incidentalotas: according to a survery of pituitary incidentalotas in Japan. Semin Ultrasound CT MR 2005;26:47-50.

  26. Howlett TA, Como J, Aron DC. Management of pituitary incidentalomas. A survey of British and American endocrinologists. Endocrinol Metab Clin North Am 2000;29:223-230.

  27. Aron DC. Hormonal screening in the patient with an incidentally discovered pituitary mass: Current practice and factors in clinical decision making. Endocrinologist 1995;5:357-363.

  28. Molitch ME. Clinical Review 65. Evaluation and treatment of the patient with a pituitary incidentaloma. J Clin Endocrinol Metab 1995;80:3-6.

  29. Molitch ME. Diagnostic evaluation update. Pituitary incidentalomas. Endocrinol Metab Clin North Am 1997;26:725-740.

  30. von Werder K. Pituitary enlargement. Clin Endocrinol 1996;44:299-303.

  31. Arafah BM, Nasrallah MP. Pituitary tumors: pathophysiology, clinical manifestations and management. Endocr Relat Cancer 2001;8:287-305.

  32. Levy A. Pituitary disease: presentation, diagnosis, and management. J Neurol Neurosurg Psychiatry 2004;75;47-52.

  33. Aron DC, Tyrrell JB, Wilson CB. Pituitary Tumors. Current concepts in diagnosis and management. West J Med 1995; 162:340-352.

  34. Schlechte JA. Clinical practice. Prolactinoma. New Engl J Med 2003;349:2035-2041.

  35. Casanueva FF, Molitch ME, Schlechte JA, Abs R, Bonert V, Bronstein MD, et al. Guidelines of the pituitary society for the diagnosis and management of prolactinomas. Clin Endocrinol 2006;65:265-273.

  36. Pickett CA. Diagnosis and management of pituitary tumors: recent advances. Prim Care 2003:30;765-789.

  37. Dombrowski RC, Romeo JH, Aron DC. Verapamil-induced hyperprolactinemia complicated by a pituitary incidentaloma. Ann Pharmacother 1995;29:999-1001.

  38. Glezer A, D´Alva CB, Salgado LR, Musolino NR, Serafíni P, Vieira JG. Pitfalls in pituitary diagnosis: peculiarities of three cases. Clin Endocrinol 2002;57:135-139.

  39. Gibney J, Smith TP, McKenna TJ. Clinical relevance of macroprolactin. Clin Endocrinol 2005;62:633-643.

  40. Gezer A, Atasu T, Hekim C, Stenman UH, Hekim N. Hyperprolactinaemia does not always mean “hyperprolactinaemia”? Eur J Obstet Gynecol Reprod Biol 2005;118:206-208.

  41. Simard MF. Pituitary tumor endocrinopathies and their endocrine evaluation. Neurosurg Clin N Am 2003;14:41-54.

  42. Mercado M. Consenso Nacional de Acromegalia. Guía para su diagnóstico, tratamiento y seguimiento. Rev Endocrinol Nutr 2004;S2,S63-S72.

  43. Holdaway IM, Rajasoorya RC, Gamble GD. Factors influencing mortality in acromegaly. J Clin Endocrinol Metab 2004;89:667-674.

  44. Colao A, Ferone D, Marzullo P, Lombardi G. Systemic complications of acromegaly: epidemiology, pathogenesis, and management. Endocr Rev 2004;25:102-152.

  45. Giustina A, Barkan A, Casanueva FF, Cavagnini F, Frohman L, Ho K, et al. Criteria for cure of acromegaly: a consensus statement. J Clin Endocrinol Metab 2000;85:526-529.

  46. Findling JW, Raff H. Screening and diagnosis of Cushing’s syndrome. Endocrinol Metab Clin North Am 2005;34:385-402.

  47. Espinosa-de-los-Monteros AL. Pruebas bioquímicas en neuroendocrinología. Rev Endocrinol Nutr 2005;S1:S7-S12.

  48. Hernández I, Espinosa-de-los-Monteros AL, Mendoza V, Cheng S, Molina M, Sosa E, et al. Ectopic ACTH- secreting syndrome: a single center experience report with a high prevalence of occult tumor. Arch Med Res 2006;37:976-980.

  49. Lindsay JR, Nieman LK. Differential diagnosis and imaging in Cushing’s syndrome. Endocrinol Metab Clin North Am 2005;34:403-421.

  50. Chaidarun SS, Klibanski A. Gonadotropinomas. Semin Reprod Med 2002;20:339-348.

  51. Greenman Y, Melmed S. Diagnosis and management of nonfunctioning pituitary tumors. Annu Rev Med 1996;47:95-106.

  52. Vance ML. Treatment of patients with a pituitary adenoma: one clinician’s experience. Neurosurg Focus 2004;16:E1.

  53. Melmed S, Casanueva F, Cavagnini F, Chanson P, Frohman LA, Gaillard R, et al. Consensus statement: medical management of acromegaly. Eur J Endocrinol 2005;153:737-740.

  54. Mortini P, Losa M, Barzaghi R, Boari N, Giovanelli M. Results of transsphenoidal surgery in a large series of patients with pituitary adenoma. Neurosurgery 2005;56:1222-1233.

  55. Elsässer Imboden PN, De Tribolet N, Lobrinus A, Gaillard RC, Portmann L, Pralong F, Gomez F. Apoplexy in pituitary macroadenoma. Medicine 2005;84:188-196.

  56. Gnanalingham KK, Bhattacharjee S, Pennington R, Ng J, Mendoza N. The time course of visual field recovery following transphenoidal surgery for pituitary adenomas: predictive factors for a good outcome. J Neurol Neurosurg Psychiatry 2005;76:415-419.




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