Martínez FM, Domínguez CG, Rivero SE

Language: Spanish
References: 16
Page: 11-16
PDF size: 85.82 Kb.

ABSTRACT

Normal adrenal function is important for modulating intermediary metabolism, blood pressure, vascular volume and electrolytes. Cortisol is the most important glucocorticoid produced by the adrenal cortex. In the critically ill patient, cortisol deficiency is associated with an increase of morbidity and mortality rate. ACTH deficiency causes secondary adrenocortical insufficiency. It has been reported low levels of ACTH in patients with sepsis and in critically illness. The incidence of adrenal insufficiency in critically ill patients is variable and is related to the original presenting illness and its severity. It is very difficult the recognition of adrenal deficiency in the ICU patient, but often hypotension refractory to treatment with electrolyte solutions and persistent low levels of serum sodio are observed. In this issue is discussed the features of adrenal deficiency in the critically ill patient and its management.

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