2008, Number 2
<< Back Next >>
Acta Ortop Mex 2008; 22 (2)
Sclerosing osteomyelitis of the femur and thrombocytosis. A casereport
Redón TA, Franco EML, Martínez CE, Romero RR, Delgado CR, Morales OMG
Language: Spanish
References: 14
Page: 120-126
PDF size: 192.03 Kb.
ABSTRACT
We present the case of a 13 year-old boy who had chronic sclerosing osteomyelitis of the right femur in whom S. aureus was confirmed as the etiologic agent. Typical picture was apparent after one year period in which there were two hospital admissions. Only soft tissue infection of the right thigh was misdiagnosed in the first admission in spite of gammagraphic evidence of bone recording at the distal right femur. In the second admission, formal bone infection with a special pattern was diagnosed as a chronic sclerosing osteomyelitis, since the following criteria were addressed: 1) clinical features of infection, 2) laboratory features for infection, 3) low-virulence bacteriae, 4) an unusually high organic and tissue reaction which involved thrombocytosis in this patient, 5) bone sclerosis and hypertrophic bone response, 6) a very slow production of pus, and 7) chronicity.
REFERENCES
Garré C: Ueber besondere Formen und Folgezustände d. akuten indekt. Osteomyelitis. Verh Dtsch Ges Pathol 1893; 10: 257.
Jones SF: Sclerosing Non suppurative Osteomyelitis as Described by Garré. Report of Case with Roentgenographic and Pathologic Findings and Review of the Literature. J Am Med Ass 1921; LXXVII: 1921.
Kurtz AD: Chronic sclerosing osteomyelitis. Report of a case. J Am Med Assn 1922; LXXVIII: 331.
Phemister DB: Silent foci of localized osteomyelitis. J Am Med Assn 1924; LXXXII: 1311.
Wishner JG: Chronic sclerosing osteomyelitis (Garré). J Bone Joint Surg 1933; 15: 723-32.
Compere EL: The operative treatment for low back pain. J Bone Joint Surg 1937; 19: 749-58.
Jaffe HL, Liechtenstein L: Further experience with this benign tumor of bone with special reference to cases showing the lesion in relation to shaft cortices and commonly misclassified as instances of sclerosing non-suppurative osteomyelitis or cortical bone abscess. J Bone Joint Surg 1940; 22: 645-82.
Wood RE, et al: Periostitis ossificans versus chronic non-suppurative osteomyelitis (Garré Osteomyelitis). Med Hyg (Geneve), 1981, 7; 39(1440): 3332-5.
Toller MO, Karaca I. Mandibular giant cell granuloma, associated with sclerosing osteomyelitis of Garré (periostitis ossificans). Oral Surg Oral Med Oral Pathol 1988; 65(6): 773-7.
Hardmeier T, Uelinger E, Muggli A: Primär chronische sklerosierende osteomyelitis. Verh Dtsch Ges Pathol 1974; 58: 474-7.
Segev E, Hayek S, Lokiec F, Ezra E, Issakov J, Wientroub S: Primary Chronic Sclerosing (Garré’s) Osteomyelitis in Children. J Pediat Orthop Br 2001; 10(4): 360-4.
Franz T, Lehman T, Eggli S. Aseptic femoral osteitis from SAPHO syndrome: Case report. Clin Orthop Relat Res 2005; 438: 277-81.
Yohannan MD, Higgy KE, al-Mashhadani SA, Santhosh-Kumar CR. Thrombocytosis. Etiologic analysis of 663 patients. Clin Pediatr (Phila). 1994; 33(6): 340-3.
Griesshammer M, Bangerter M, Sauer T, Wennauer R, Bergmann L, Heimpel H: Aetiology and clinical significance of thrombocytosis: analysis of 732 patients with an elevated platelet count. J Intern Med 1999; 245(3): 295-300.