1998, Number 1
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Vet Mex 1998; 29 (1)
Propofol, a new anaesthetic drug in veterinary medicine
Redondo GJI, Gómez VR, Santisteban VJM, Ruiz CI, Domínguez PJM, Ávila JI
Language: English/Spanish
References: 61
Page: 101-110
PDF size: 968.50 Kb.
ABSTRACT
Propofol is an anaesthetic drug of recent use in veterinary anaesthesiology. Its pharmacological characteristics, cardiopulmonary effects and the degree of analgesia and muscular relaxation supplied make it an excellent drug. Furthermore, its association with different preanaesthetic drugs permits its use in many anaesthetic regimens, either as an inductor previous to the inhalatory anaesthesia or as a maintenance anaesthetic administered by infusion. The recovery from anaesthesia is excellent, fast, smooth and peaceful. Apnoea and vomiting have been described as collateral effects.
REFERENCES
Watkins SB, Hall LW, Clarke KW. Propofol as an intravenous agent in dogs. Vet Rec 1987;120:326-329.
Simons PJ, Cockshott ID, Douglas EJ, Gordon EA. Disposition in male volunteers of subanaesthetic intravenous dose of an oil in water emulsion of 14-C-propofol (Diprivan). Xenobiotica 1988;18:429-440.
Ezquerra-Calvo LJ, Vives-Vallés MA, Usón-Gargallo J. Anestesia práctica de pequeños animales. Madrid, Espatia: McGraw-Hill-Interamericana, 1992.
White PF. Clinical uses of intravenous anesthetic and analgesic infusion. Anesth Analg 1989;68:161-171.
Nolan AM, Reid J, Grant S. The effect of halothane and nitrous oxide on the pharmacokinetics of propofol in dogs. J Vet Pharmacol Ther 1993;16:335-342.
James R, Glen JB. Synthesis, biological evaluation, and preliminary structure-activity considerations of a series of alkilphenols as intravenous anaesthetic agents. J Med Chem 1980;23:1350-1357.
Glen JB. Animal studies of the anaesthetic activity of ICI 35 868. Br J Anaesth 1980;52:731-741.
Briggs LP, Clarke RSJ, Watkins J. An adverse reaction to the administration of propofol (Diprivan). Anaesthesia 1982;37:1099-1101.
Glen JB, Hunter SC. Pharmacology of an emulsion formulation of ICI 35 868. Br J Anaesth 1984;56:617-625.
Zoran DL, Riedesel DH, Dyer DC. Pharmacokinetics of propofol in mixed-breed dogs and Greyhounds. Am J vet Res 1993;54:755-760.
Schuttler J, Stoeckel H, Schwilden H. Pharmacokinetic and pharmacodynamic modelling of propofol (Diprivan) in volunteers and surgical patients. Postgrad Med J 1985;61:53-54.
Kanto J, Gepts E. Pharmacokinetic implications for the clinical use of propofol. Clin Pharmacokinet 1989;17:308-326.
Vainio O. Propofol infusion anaesthesia in dogs pre-medicated with medetomidine. J vet Anaesth 1991;18:35-37.
Bentley GN, Gent JP, Goodchild CS. Vascular effects of propofol: smooth muscle relaxation in isolated veins and arteries. J Pharm Pharmacol 1989;41:797-798.
Goodchild CS, Serrao JM. Cardiovascular effects of propofol in the anaesthetized dog. Br J Anaesth 1989;63:87-92.
Thurmon JC, Ko JCH, Benson GJ, Tranquilli WJ, Olson WA. Hemodynamic and analgesic effects of propofol infusion in medetomidine-premedicated dogs. Am J vet Res 1994;55:363-367.
Vainio O, Palmu L. Cardiovascular and respiratory effects of medetomidine in dogs and influence of anticholinergics. Acta Vet Scand 1989;30:401-408.
Cullen LK, Reynoldson JA. Xylazine or medetomidine premedication before propofol anaesthesia. Vet Rec 1993;132:378-383.
Smith JA, Gaynor JS, Bednarsky RM, Muir WW. Adverse effects of administration of propofol with various preanesthetic regimens in dogs. J Am vet med Assoc 1993;202:1111-1115.
Keegan RD, Greene SA. Cardiovascular effects of a continuous two-hour propofol infusion in dogs. Vet Surg 1993;22:537-543.
Cullen LK, Reynoldson JA. The effects of tiletamine/zola zepam premedication on propofol anaesthesia. Scientific Abstracts of the 5th International Congress of Veterinary Anesthesia; 1994 August 21-25; Guelph: Canada. Guelph, Canada: American College of Veterinary Anesthesiologists, Ontario Veterinary College and University of Guelph, 1994:181.
Ilkiw JE, Pascoe PJ, Haskins SC, Patz JD. Cardiovascular and respiratory effects of propofol administration in hypovolemic dogs. Am J vet Res 1992;53:2323-2327.
Robertson SA, Johnson S, Beemsterboe Jr. Cardiopulmonary, anesthetic, and postanesthetic effects of intravenous infusions of propofol in Greyhounds and in non-Greyhounds. Am J vet Res 1992;53:1027-1032.
Hall LW, Chambers JP. A clinical trial of propofol infusion anaesthesia in dogs. J Small Anim Pract 1987;28:623-637,
Mandsanger RE, Shawley RV, Clark DM. Evaluation of propofol or acepromazine/diazepam/ketamine in the Greyhound. Vet Surg 1991;20:80-81.
Haskins SC, Farver TB, Patz JD. Ketamine in dogs. Am J vet Res 1985;46:1855-1860.
Kamibayashi T, Hayashi Y, Sumikawa K, Yamatodani A, Kawabata K, Yoshiya I. Enhancement by propofol of epinephrine-induced arhythmias in dogs. Anesthesiology1991;75:1035-1040.
Sebel PS, Lowdon JD. Propofol: a new intravenous anesthetic. Anesthesiology 1989;71:260-277.
Pagel PS, Warltier DC. Negative inotropic effect of propofol as evaluated by regional preload recruitable stroke work relationship in chronically instrumented dogs. Anesthesiology 1993;78: 100-108.
Muir WW, Hubbell JAE. Blood pressure response to acetylpromazine and lamperone in halothane anesthetized dogs. J Am Anim Hosp Assoc 1985;21:285-289,
Muir WW, Hubbell JAE. Handbook of veterinary anesthesia. St. Louis (MO): CV Mosby Company, 1989.
Skues MA, Richards MJ, Jarvis AP et al. Preinduction atropine or glycopyrrolate and hemodynamic changes associated with induction and maintenance of anesthesia with propofol and alfentanil. Anesth Analg 1989;69:386-390.
Edelist GA. A comparison of propofol and thiopentone as induction agents in our patient surgery. Can J Anaesth 1987;34:106-110.
Grounds RM, Morgan M, Lumley J. Some studies on the properties of the intravenous anaesthetic propofol ("Diprivan") a review. Postgrad Med J 1985;61(Suppl):90-95.
Muir WW, Mason DE. Side effects of etomidate in dogs. J Am Anim Hosp Assoc 1989; 194: 1430-1434.
Nagel MC, Muir WW, Nguyen K. Comparison of cardiopulmonary effects of etomidate and thiamylal in dogs. Am J vet Res 1979;40:193-196.
Goodman NW, Black AMS, Carter JA. Some ventilatory effects of propofol as sole anaesthetic agent. Br J Anaesth 1987;59:1497-1503.
Taylor MB, Grounds RM, Mulrooney PD, Morgan M. Ventilatory effects of propofol during induction of anaesthesia. Comparison with thiopentone. Anaesthesia 1986;41:816-820.
Clarke KW, England GCW. Medetomidine, a new sedativeanalgesic for use in the dog and its reversal with atipamezol. J Small Anim Pract 1989;30:343-348.
Tagawa M, Hara Y, Ejima H. Effect of propofol drip infusion following pretreatment with medetomidine and butorphanol on cardiopulmonary function in the dog. Scientific Abstracts of the 5th International Congress of Veterinary Anesthesia; 1994 August 21-25; Guelph, Canada. Guelph Canada: American College of Veterinary Anesthesiologists, Ontario Veterinary College and University of Guelph, 1994: 175.
Funkquist P, Peterson C. Propofol- ett nytt narkosmedel för hund och katt. Svensk Veterinär Tidning 1991;43:555-559.
Greel JK. The effect of premedication on the induction dose of propofol in dogs and cats. J S Afr Vet Assoc 1991;62:118-123.
Morgan DWT, Legge K. Clinical evaluation of propofol as an intravenous anaesthetic agent in cats and dogs. vet Rec 1989;124:31-33.
Fragen RJ, Shanks CA. Anesthetic induction characteristics of Diprivan (propofol) emulsion. Semin Anesth 1988;7:103-107.
Sung YF, Weinstein MS, Biddle MR. Comparison of Diprivan (propofol) and thiopental as intravenous induction agents: cardiovascular effects, respiratory change, recovery, and postoperative venous siquelae. Semin Anesth 1988;7:52-56.
Ponte J, Sadler CL. Effect of thiopentone, etomidate and propofol on carotid body chemoreceptor activity in the rabbit and cat. Br J Anaesth 1989;62:41-45.
Blair E. Hypotermia. In: Soma LR, editor. Textbook of veterinary anesthesia. Baltimore: Williams & Wilkins Co., 1971:555-579.
Dale HE, Elefson EE, Niemeyer KH. Influence of environmental temperature on recovery of dogs from pentobarbital anesthesia. Am J vet Res 1968;29:1339-1347.
Komar E, Lipp J. Propofol anesthesia in dogs. Scientific Abstracts of the 5th International Congress of Veterinary Anesthesia; 1994 August 21-25; Guelph, Canada. Guelph, Canada: American College of Veterinary Anesthesiologists, Ontario Veterinary College and University of Guelph, 1994:205.
Komar E, Silmanowicz P, Balicki J. Wplyw anestezji propofolem na wymiane gazowq i parametry hematologiczne u psów. Medycyna Wet 1993;49:30-32.
Davies C. Excitatory phenomena following the use of propofol in dogs. J Assoc Vet Anaesth 1991;18:48-51.
Way WL, Trevor AJ. Pharmacology of intravenous nonnarcotic anesthetics. In: Miller RD, editor. Anesthesia. 2nd ed. Vol 2. New York (NY): Churchill Livingstone, 1986:799-833.
Weaver BMQ, Raptopoulos D. Induction of anaesthesia in dogs and cats with propofol. Vet Rec 1990;126:617-620.
Klement W, Arndt JO. Pain on injection of propofol: Effects of concentration and diluent. Br J Anaesth 1991;67:281-284.
Reid J. Nolan AM. Pharmacokinetics of propofol in dogs premedicated with acepromazine and maintained with halothane and nitrous oxide. J Vet Pharmacol Ther 1993;16:501-505.
Cotard JP. La fibroscopie chez le chien et le chat. Actas de las IV Jornadas Internacionales de Cirugla Veterinaria; 1995 marzo 10-11; Córdoba, España. Cordoba, España: Sociedad Española de Cirugía Veterinaria, 1995:189-196.
Combrisson H, Robain G, Cotard JP. Comparative effects of xylazine and propofol on the urethral pressure profile of healthy dogs. Am J vet Res 1993;54:1986-1989.
Pedrick TP. Short CE, Bufalari A, Hardie RJ, Giannoni C. Evaluation of perioperative analgesia by electroencephalography in propofol-halothane and medetomidine-propofol-halothane anesthetized dogs during laparoscopy and laparatomy. Scientific Abstracts of the 5th International Congress of Veterinary Anesthesia; 1994 August 21-25; Guelph, Canada. Guelph, Canada: American College of Veterinary Anesthesiologists, Ontario Veterinary College and University of Guelph, 1994:159.
Robinson EP, Sams RA, Muir WW. Barbiturate anesthesia in Greyhound and mixed-breed dogs: comparative cardiopulmonary effects, anesthetic effects, and recovery rates. Am J vet Res 1986;47:2105-2112.
Bogan J. Factors affecting duration of thiopenthone anaesthesia in dogs with particular reference to Greyhounds. Proceedings of the Association of Veterinary Anaesthesiologists of Great Britain and Ireland; 1970 April 9, London, UK. London (UK): Association of Veterinary Anaesthesiologists of Great Britain and Ireland, 1970: 18-24.
Haskins SC, Farver TB, Patz JD. Cardiovascular changes in dogs given diazepam and diazepam-ketamine. Am J vet Res 1986;47:795-798.