2007, Number 4
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Gac Med Mex 2007; 143 (4)
Síntomas depresivos como factor de riesgo para polifarmacia en pacientes mayores de 60 años
Granados-Ponce JA, Peralta-Pedrero ML, Munguía-Miranda C, López-Carmona JM, Ávila-Leyva A, Rodríguez-Moctezuma R
Language: Spanish
References: 19
Page: 285-289
PDF size: 53.86 Kb.
ABSTRACT
Objective: To determine the association between depressive symptoms not identified by the family physician and polypharmacy in patients over 60 years old.
Methods: A case-control design with non-probabilistic sampling. Inclusion criteria: ≥ 60 years old both sexes, without disease or with one disease-balanced illness, and with reliable recording in chart by the last 12 month. Exclusion criteria: cognitive deterioration, obstructive chronic lung disease, cardiopathy, infarct record, alcoholism, smoking addiction and functional dependence’s. Elimination criteria: depression’s previous diagnoses and hospitalization during a year before the study. The cases were patients who have simultaneously received 4 o more pharmacologic prescriptions in 5 of 6 last medical visits. The controls were patients who have simultaneously received 3 o less pharmacologic prescriptions in 5 of 6 last medical visits. Depressive symptoms: grading ≥ 6 (Yesavage and Brink scale).
Results: 200 patients per group, aged 69 ± 6 years agreed to participate. Logistics regression (OR;CI
95%): hypertension (6.0;3.6- 10.3), diabetes mellitus type 2 (3.7;2.3-5.9), depression (2.1;1.2- 3.4), and female sex (1.7;1.1-2.7).
Conclusions: Hypertension, diabetes mellitus type 2, depressive symptoms not identified by the family physician, and female sex are risk factors for polypharmacy in the elderly.
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