Sánchez HJ, Mejía LS, Zapata IL, Rodríguez MA, García RE

Language: Spanish
References: 34
Page: 16-21
PDF size: 81.60 Kb.

ABSTRACT

Antecedents. Although Helicobacter pylori (HP) is the main cause of chronic gastritis, it still does not exist relation between dyspeptic symptoms and improvement of such after eradicating the bacterium. Objective. To value and compare the effectiveness of three therapeutic schemes, for eradication and improvement of the symptoms of the patients with dyspepsia, gastritis and HP. Methodology. Prospective, longitudinal, comparative study. It was made endoscopy and biopsy of the gastric mucosa to all the patients. They received treatment with three different random selected schemes and clinical evaluation and breath test for eradication of HP were made. Results. 60 patients with age average of 49 years, 39 women and 21 men were included. Group A received three drugs in a single package (pylopac) during seven days, they had improvement in 61.9% and eradication of 85.7%. Group B received three drugs by 14 days, with improvement of the symptoms of 47,6% and eradication of 66.6%. Group C received four drugs during seven days with improvement of 77,7% and eradication of 66.6%. Conclusions. There was no correlation between the improvement of the symptoms and the eradication of HP in none of the three groups. The persistence of the symptoms was superior in group C (77.7%) in comparison with group B (47.6%). Also, the eradication in the group A was superior (85.7%) that group B and C (66%).

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