medigraphic.com
ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2004, Number 3

<< Back Next >>

An Med Asoc Med Hosp ABC 2004; 49 (3)

Infantile digital fibromatosis. A case report

León BB, Fernández VJM

Language: Spanish
References: 17
Page: 147-150
PDF size: 83.47 Kb.


ABSTRACT

Inclusion body fibromatosis, so-called infantile digital fibromatosis is a benign proliferation of fibroblastic and myofibroblastic cells that typically occur on the dorsal aspect of digits of hand and feet of young children. It is named for the intracytoplasmic inclusions that are detected in some of the lesional cells. It is a rare tumor, the nodule usually is less than 2.0 cm in diameter, local recurrence occurs in about 50% of cases. More than one digit may be affected synchronously and asynchronously, and some of them regress spontaneously. A ten-year-old boy was seen with a painless tumor on the rigth ring finger, measuring 1.5 cm, and it was surgically removed. The histopathological findings showed a spindle cells proliferation in fascicles associated with varying amounts of extracellular collagen. The diagnostic feature was the presence of intracytoplasmic, eosinophilic spherical inclusions with variable staining for actin, and the ultrastructure showed a granular and filamentous appearance, typical of actin filaments. Four months later the patient develop another tumor on the little finger of the right hand that was also surgically removed too. This patient showed the typical localization and evolution of this particular fibromatosis with inclusion body in a child.


REFERENCES

  1. Reye RDK. Recurring digital fibrous tumor of childhood. Arch Pathol 1965; 80: 228-231.

  2. Rimareix F, Bardot J, Andrac L, Vasse D, Galinier P, Magalon G. Infantile digital fibroma-report on eleven cases. Eur J Pediatr Surg 1997; 7: 345-348.

  3. Kanwar AJ, Kaur S, Thami GP, Mohan H. Congenital infantile digital fibromatosis. Pediatr Dermatol 2002; 19: 370-371.

  4. SungurN, Kilinc H, Ozdemir R, Sensoz O, Ulusoy MG. Infantile digital fibromatosis: An unusual localization. J Pediatr Surg 2001; 36: 1587-1589.

  5. Plusje LG, Bastiaens M, Chang A, Hogendoorn PC. Infantil-type digital fibromatosis tumour in an adult. Br J Dermatol 2000; 143: 1107-1108.

  6. Dabney KW, MacEwen GD, Davis NE. Recurring digital fibrous tumor of childhood: Case report with long-term follow up and review of the literature. J Pediatr Orthop 1986; 6: 612-617.

  7. Kawaguchi M, Mitsuhashi Y, Hozumi Y, Kondo S. A case of infantile digital fibromatosis with spontaneous regression. J Dermatol 1998; 25: 523-526.

  8. Duran-McKinster C, Herrera M, Reyes-Mugica M, Ruiz-Maldonado R. Infantile digital fibromatosis: spontaneous regression in three cases. Eur J Dermatol 1993; 3192-3194.

  9. Viale G, Doglione C, Iuzzolino P, Bontempini L, Colombi R, Coggi G, Dell’Orto P. Infantile digital fibromatosis-like tumour (inclusion body fibromatosis) of adulthood: report of two cases with ultrastructural and immunocytochemical findings. Histopathology 1988; 12: 415-424.

  10. Pettinato G, Manivel JC, Gould EW, Albores-Saavedra J. Inclusion body fibromatosis of the breast. Two cases with immunohistochemical and ultrastructural findings. Am J Clin Pathol 1994; 101: 714-718.

  11. Yusoff Kl, Spagnolo DV, Digwood KI. Atypical cervical polyp with intracytoplasmic inclusions. Pathology 1998; 30: 215-217.

  12. Hiraoka N, Mukai M, Hosoda Y, Hata J. Phyllodes tumor of the breast containing intracytoplasmic bodies identical with infantile digital fibromatosis. Am J Surg Pathol 1994; 18: 506-511.

  13. O’Connell (2002). Inclusion body fibromatosis. In: Fletcher CDM, Unni KK, Mertens F. WHO Classification of tumours. Pathology and genetics of tumours of soft tissue and bone. Lyon: IARCPress, 64-65.

  14. Baery J, Murphy JJ, Magee JF. Fibromatoses: Clinical and pathological features suggestive of recurrence. J Pediatr Surg 1999; 34: 1112-1114.

  15. Hayashi T, Tsuda N, Cowdhury PR, Anami M, Kishikawa M, Iseki M, Kobayashi K. Infantile digital fibromatosis: A study of the development and regression of cytoplasmic inclusion bodies. Modern Pathol 1995; 8: 548-552.

  16. Miyamoto T, Mihara H, Hagari Y, Shimao S, Nakahara T, Kimura M. Posttraumatic occurrence of infantil digital fibromatosis, a histologic and electron microscopic study. Arch Dermatol 1986; 122: 915-918.

  17. Kawabata H, Masada K, Aoki Y. Infantile digital fibromatosis after web construction in syndactilia. J Hand Surg (Am) 1986; 11: 741-743.




2020     |     www.medigraphic.com