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Federación Mexicana de Ginecología y Obstetricia, A.C.

2006, Number 09

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Ginecol Obstet Mex 2006; 74 (09)

Thyroid dysfunctions and pregnancy

Briceño PC, Briceño SL

Language: Spanish
References: 31
Page: 462-470
PDF size: 329.30 Kb.


ABSTRACT

Objective: To study thyroid dysfunctions during pregnancy.
Patients and method: Descriptive, transversal and retrospective study of 61 thyroid dysfunctions during pregnancy, from January 1982 to December 2002.
Results: There were 44 hyperthyroidism (1 in 1,908 deliveries: 0.05%) and 17 hypothyroidism (1 in 4,939: 0.02%). Main findings in hyperthyroid patients were: 30-34 years and 2 gestations (34.11%), arterial hypertension (15.90%), abortions (9.09%), preterm delivery (9.09%), term delivery (56.82%), cesarean section (25%), medical treated (97.78%), fetal weighs 3,000-3,499 g (25.61%), 1 and 5 minutes Apgar 8-10 points (60.54 and 81.59%), perinatal mortality rate 0.07 per 1,000 and there was no maternal mortality. And in hypothyroid women: 25-29 years (64.72%), one gestation (29.44%), abortions (17.64%), premature rupture of membranes and oligoamnios (17.64%), term delivery (35.28%), medical treated (100%), fetal weighs 2,500-2,999 g (56.25%), 1 and 5 minutes Apgar 8-10 points (78.58% and 78.58%) and there was no preterm delivery and perinatal or maternal mortality.
Conclusions: Thyroid dysfunctions are infrequent in pregnancy and have little repercussions in perinatal morbidity and mortality.


REFERENCES

  1. Schroeder B. ACOG Practice Bulletin. Clinical management guidelines for obstetrician and gynecologists. Obstet Gynecol 2002;100:387-96.

  2. 2. Thorpe-Beeston J, Nikolaides K. Maternal and fetal thyroid function in pregnancy. London: The Parthenon Publishing Group, 1996.

  3. 3. Glinoer D. The regulation of thyroid function in pregnancy: pathways of endocrine adaptation from physiology and pathology. Endocr Rev 1997;18:404-33.

  4. 4. Cooper D, Ladenson P. Diseases of the thyroid. Clinical Updates in Women’s Health Care ACOG 2003;11:1-80.

  5. 5. Corredor A, Bossio B, P. de Velásquez R. Hipertiroidismo y embarazo. Rev Obstet Ginecol Venez 1980;40:223-6.

  6. 6. Nachum Z, Rakover Y, Weiner E, Shalev E. Grave’s disease in pregnancy: prospective evaluation of a selective invasive treatment protocol. Am J Obstet Gynecol 2003;189:159-65.

  7. 7. Rivera M, Morales M, Mendieta E, et al. Hipertiroidismo neonatal: informe de un caso. Bol Med Hosp Infant Mex 1994;51:473-6.

  8. 8. Sheffield J, Cunningham G. Thyrotoxicosis and heart failure that complicate pregnancy. Am J Obstet Gynecol 2004;190:211-7.

  9. 9. Franco J. Hipotiroidismo y embarazo: actualización clínica. Med Univ (México) 2005;7:76-82.

  10. Mestman J. Hyperthyroidism in pregnancy. Clin Obstet Gynecol 1997;40:45-64.

  11. Zárate A, Ruiz E, Vinueza G, Canales E. Tiroidopatías y embarazo. Ginecol Obstet Mex 1982;50:127-32.

  12. Mestman J. Diagnosis and management of hyperthyroidism in pregnancy. Curr Probl Obstet Gynecol 1981;4:10.

  13. Zárate A, Canales E, Mc Gregor C, Castelazo L. Endocrinología ginecológica y del embarazo. México: La prensa médica mexicana, 1982;pp:161-4.

  14. Palacios H, Solís J. Hipertiroidismo en gestación. Clínica, morbi-mortalidad materna, fetal y perinatal. Rev Med Her (Perú) 1995;6:107-14.

  15. Kamijo K, Saito T, Sato M, et al. Transient subclinical hypothyroidism in early pregnancy. Endocrinol Jpn 1990;37:397-403.

  16. Montoro M, Collea J, Frasier S, Mestman J. Successfull outcomes of pregnancy in women with hypothyroidism. Ann Intern Med 1981;94:31-34.

  17. Montoro M. Management of hypothyroidism during pregnancy. Clin Obstet Gynecol 1997;40:65-80.

  18. Forsbach G, Cano C, Moriyon R, Canales E, Zárate A. Amenorrea, galactorrea e hipotiroidismo primario: informe de un caso y revisión de la literatura. Rev Invest Clin (México) 1981;33:293-7.

  19. Leung A, Millar L, Koonings P, Montoro M, Mestman J. Perinatal outcome in hypothyroid pregnancies. Obstet Gynecol 1993;81:349-53.

  20. Buckshee K, Kriplani A, Kapil A, Bhargava V, Takkar D. Hypothyroid complicating pregnancy. Aust NZ J Obstet Gynecol 1992;32:240-2.

  21. Lejeune B, Lemoine M, Kinthaer J. The epidemiology of autoimmune and functional thyroid disorders in pregnancy. J Endocrinol Clin 1992;15(S2):77.

  22. Klein R, Haddow J, Faix J, et al. Prevalence of thyroid deficiency in pregnant women. Clin Endocrinol 1991;35:41-46.

  23. Salinas A, Urquieta M, Peñaranda J, Huaricallo E, San Miguel J. Evaluación clínica de la glándula tiroides y de la hormona estimulante de la tiroides (TSH) y T4 libre en mujeres de nivel socioeconómico bajo. Cuad Hosp Clin (Bolivia) 2001;47:19-30.

  24. Sullivan M. Subclinical hypothyroidism before conception. ObGyn News 2004;39:1-4.

  25. American Thyroid Association (ATA). Statement on early maternal thyroidal insufficiency: recognition, clinical management and research directions. 2004.

  26. Millar L, Wing D, Leung A. Low birth weight and preeclampsia in pregnancies complicated by hypertiroidism. Obstet Gynecol 1994;84:946-9.

  27. Davis L, Lucas M, Hankins G. Thyrotoxicosis complicating pregnancy. Am J Obstet Gynecol 1989;160:63-70.

  28. Hernández T, Pérez-Rulfo C, Monteros A. Hipertiroidismo y embarazo. Ginecol Obstet Mex 1983;51:297-300.

  29. Davis L, Leveno K, Cunningham F. Hypothyroidism complicating pregnancy. Obstet Gynecol 1988;72:108-12.

  30. Pop V, De Vries E, Van Baar A, et al. Maternal thyroid peroxidase antibodies during pregnancy: a marker of impaired child development? J Clin Endocrinol Metab 1995;80:3561-5.

  31. Zárate A, Canales E, Cano C, Castelo J, Ruíz J. Manejo del hipertiroidismo durante el embarazo. Rev Invest Clín (México) 1982;34:317-9.




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