Posadas CJG, Ugarte TA, Domínguez CG

Language: Spanish
References: 16
Page: 210-215
PDF size: 276.84 Kb.

ABSTRACT

Introduction: Pheochromocytoma is a catecholamine secreting tumor derived from chromaffin tissue. It is characterized by severe hypertension, arrhythmias and hyperglycemia, and represents less than 0.2% of hypertensive patients.
Objective: To describe the characteristics of a group of patients with pheochromocytoma.
Material and method: We reviewed all the records from patients with pheochromocytoma admitted from 1987 to 2002 in a Mexican institution. We obtained data from medical history, location, medical and surgical treatment and complications.
Results: 23 patients were included; 73.9% were women. Mean age was 38.3 ±, 15.4 years old. There were 20 (86.9%) sporadic cases, 2 (8.7%) associated with multiple endocrine neoplasia II syndrome and 1 associated with (4.3%) Von Hippel-Lindau disease. Abdomen scan was made in 22 patients, with sensitivity and specificity of 95 and 100%, respectively. Four nuclear magnetic resonance, and four metaiodo-benzilguanidine studies were made, with sensitivity and specificity of 100%. Likewise, ultrasonography was made in three patients, with sensitivity of 66%. Open surgery was made in 14 (60.9%) patients and laparoscopy in 9 (39.1%) of them.
Conclusion: People with one year or less of hypertension evolution have 5.6 times more possibilities of getting cured after surgery than people with symptoms of more than one year of evolution (OR 5.6, CI 95%: 1.4-21.7; p = 0.003).

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