2007, Number 4
<< Back Next >>
Rev Inst Nal Enf Resp Mex 2007; 20 (4)
The influence of diabetes mellitus type 2 upon the prevalence of respiratory diseases at the National Institute of Respiratory Diseases Ismael Cosío Villegas
García-Sancho FMC, Castillejos LM, Fernández PMR, Fabián SMMG, Torres-Espíndola LM
Language: Spanish
References: 23
Page: 259-264
PDF size: 76.92 Kb.
ABSTRACT
Background: The burden of respiratory diseases associated to type 2 diabetes
mellitus (DM2) is not well known. Our objective was to determine the frequency of respiratory diseases in adult patients with and without DM2.
Method: A retrospective analysis of database for discharged patients from the INER during 2005 was done. Patients were classified as DM2 if they had the diagnosis of DM2 in the discharge diagnosis list. The main respiratory diagnoses were classified according to The International Classification of Diseases. Prevalence was calculated using the number of discharges with the disease as numerator and the total number of discharges during the same period as denominator. Subjects with HIV infection were analyzed separately.
Results: Prevalence of DM2 in HIV negative patients ≥ 18 years old was (1,430/25,925) 5.5%
vs. (5/1,011) 0.5% in HIV positive patients. Prevalence of infectious diseases in patients with and without DM2 patients was: pulmonary tuberculosis (PTb) 13.1%
vs. 3.5%, OR = 4.1, (95%CI 3.4-4.9), p ‹ 0.0001; tuberculosis sequelae 3.9%
vs. 2.8%, OR =1.3 (95%CI 1.02-1.8), p = 0.02 and non specified pneumonia 10.5%
vs. 5.7%, OR = 1.9 (95%CI 1.6-2.3), p ‹ 0.0001. The attributed population risk for infectious diseases due to DM2 in HIV negative patients was 45%. The risk of PTb was also higher in HIV positive patients with DM2. There were no differences in noninfectious respiratory diseases among negative and positive HIV patients. Respiratory infectious diseases were more frequent in DM2 patients.
Conclusions: DM2 control can reduce potentially avoidable admission rates at third level hospitals.
REFERENCES
Fagot-Campagna A, Bourdel-Marchasson I, Simon D. Burden of diabetes in an aging population: prevalence, incidence, mortality, characteristics and quality of care. Diabetes Metab 2005;31 Spec No 2:5S35-5S52.
World Health Organization. The World Health Report: Today’s challenges. (http://www.who.int/whr/2003/en). Geneva, World Health Organization.
Aguilar-Salinas CA, Velazquez Monroy O, Gomez-Perez FJ, et al; and Encuesta Nacional de Salud 2000 Group. Characteristics of patients with type 2 diabetes in Mexico: Results from a large population-based nationwide survey. Diabetes Care 2003;26:2021-2026.
Rull JA, Aguilar-Salinas CA, Rojas R, Ríos-Torres JM, Gómez-Pérez FJ, Olaiz G. Epidemiology of type 2 diabetes in Mexico. Arch Med Res 2005;36:188-196.
Secretaría de Salud. Encuesta Nacional de Salud y Nutrición 2006. Disponible en: www.todoendiabetes. org/diabe2/pdf/ensanut2006.pdf
World Health Organization. International Statistical Classification of Diseases and Related Health Problems. 10th Revision, version for 2007. Disponible en: http://www.who.int/classifications/apps/icd/icd10online/
Ponce de León A, Garcia-Garcia M de L, Garcia-Sancho MC, et al. Tuberculosis and diabetes in southern Mexico. Diabetes Care 2004;27:1584-1590.
Perez-Guzman C, Torres-Cruz A, Villarreal-Velarde H, Salazar-Lezama MA, Vargas MH. Atypical radiological images of pulmonary tuberculosis in 192 diabetic patients: a comparative study. Int J Tuberc Lung Dis 2001;5:455-461.
Perez-Guzman C, Torres-Cruz A, Villarreal-Velarde H, Vargas MH. Progressive age-related changes in pulmonary tuberculosis images and the effect of diabetes. Am J Respir Crit Care Med 2000;162:1738-1740.
Bashar M, Alcabes P, Rom WN, Condos R. Increased incidence of multidrug-resistant tuberculosis in diabetic patients on the Bellevue Chest Service, 1987 to 1997. Chest 2001;120:1514-1519.
Ismail Y. Pulmonary tuberculosis-a review of clinical features and diagnosis in 232 cases. Med J Malaysia 2004;59:56-64.
Falguera M, Pifarre R, Martin A, Sheikh A, Moreno A. Etiology and outcome of community-acquired pneumonia in patients with diabetes mellitus. Chest 2005;128:3233-3239.
Segado Soriano A, Lopez Gonzalez-Cobos C, Granda Martin MJ, Villalba Garcia M, Gil Gonzalez J, Farfan Sedano A. Infectious pathology in diabetic patients cared for in an emergency department. An Med Intern 1999;16:3-7.
Komatsu K, Kanda T. Atypical lung abscess occurring in an elderly female suffering from diabetes mellitus-a case report. Kansenshogaku Zasshi 1997;71:260-263.
Bykov VP, Piir NG. Acute abscesses and gangrene of the lungs in patients with diabetes. Klin Med (Mosk) 1990;68:76-78.
Wang XC, Huang XJ, Zhang T, et al. The characteristics of opportunistic infections in 181 HIV/AIDS patients in China. Zhonghua Nei Ke Za Zhi 2007;46:379-382.
García Sancho MC, Pérez GLE, Franco MF, Reyes TG. Infecciones oportunistas pulmonares en pacientes con infección por el virus de la inmunodeficiencia humana del Instituto Nacional de Enfermedades Respiratorias, 1991-2001. Rev Inst Nal Enf Resp Mex 2003;16:6-10.
Yamagishi F. The clinical features for tuberculosis in compromised hosts. Kekkaku 2006;81:631-638.
API Consensus Expert Committee. API TB Consensus Guidelines 2006: Management of pulmonary tuberculosis, extra-pulmonary tuberculosis and tuberculosis in special situations. J Assoc Physicians India 2006;54:219-234.
Enomoto T, Usuki J, Azuma A, Nakagawa T, Kudoh S. Diabetes mellitus may increase risk for idiopathic pulmonary fibrosis. Chest 2003;123:2007-2011.
Usuki J, Enomoto T, Azuma A, Matsuda K, Aoyama A, Kudoh S. Influence of hyperglycemia to the severity of pulmonary fibrosis. Chest 2001;120(1 Suppl):71-73.
Asanuma Y, Fujiya S, Ide H, Agishi Y. Characteristics of pulmonary function in patients with diabetes mellitus. Diabetes Res Clin Pract 1985;1:95-101.
Saxena S, George J, Barber J, Fitzpatrick J, Majeed A. Association of population and practice factors with potentially avoidable admission rates for chronic diseases in London: cross sectional analysis. J R Soc Med 2006;99:81-89.