2007, Number 4
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Arch Cardiol Mex 2007; 77 (4)
Kawasaki disease: A rare pediatric pathology in Mexico Twenty cases report from the Hospital Infantil del Estado de Sonora
Sotelo N, González LA
Language: English
References: 42
Page: 299-307
PDF size: 162.53 Kb.
ABSTRACT
Background: Kawasaki disease (KD) is an etiological illness that is relatively unknown and scarcely identified in Mexico; it affects children mainly aged 1–4 years, evolves with fever, vasculitis in diverse organs, and in the heart the disease mainly affects the coronary arteries.
Objectives: Our aim was to inform the clinical findings and evolution of 20 patients diagnosed with KD. Materials and methods: We reviewed the patient clinical files retrospectively and descriptively to obtain information with regard to age, sex, clinical signs, laboratory and consultory results, echocardiography findings, complications, evolution during hospitalization, follow-up, and out-patient ambulatory consultations.
Results: Eighteen patients were male, two were female, six developed coronary damage, two aortic mitral-valve insufficiency, one pericardial shedding, and one, myocarditis. All patients received gamma globulin treatment with aspirin, and 16 were controlled during 6–8 months after the acute medical profile.
Conclusions: The opportune clinical diagnostic it is fundamental to establish an early treatment with gammmaglobuline to avoid injuries in the arterial coronary level. This injury may cause eventualy ischemia or myocardial infarct.
REFERENCES
Kawasaki T, Kosaki F: Febrile oculo-orocutaneous acrodesquamatous syndrome with or without acute non-suppurative cervical lymphadenitis in infancy and childhood: clinical observations of 50 cases. Allergy 1967; 16: 178-222.
Newburger JW, Takahashi M, Gerber MA, Gewitz MH, Tani LY, Burns JC, et al: Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young, American Heart Association. Diagnosis, treatment, and long term management of Kawasaki disease: a statement for health professionals from the Committee on Rheumatic Fever, Endocarditis and Kawasaki Disease, Council on Cardiovascular Disease in the Young. Circulation 2004; 110: 2747-2771.
Burns JC, Glode MP: Kawasaki syndrome. Lancet 2004; 364: 533-544.
Rocholl C, Gerber K, Daly J, Pavia AT, Byington CL: Adenoviral infections in children: the impact of rapid diagnosis. Pediatrics 2004; 113: 51-56.
Esper F, Shapiro ED, Weibel C, Ferguson D, Landry ML, Kahn JS: Association between novel human coronarovirus and Kawasaki disease. J Infect Dis 2005; 191: 499-502.
Falcini F: Kawasaki disease. Curr Opin Rheumatol 2006; 18: 33-38.
Rodríguez-Suárez S: Síndrome linfomucocutáneo. Bol Med Hosp Infant Mex 1977; 34: 53-57.
Vizcaíno-Alarcón A, Arévalo-Salas A, Rodríguez-López AM, Sadowinski PS: Enfermedad de Kawasaki en niños mexicanos. Bol Med Hosp Infant Mex 1991; 48: 398-408.
Rodríguez-Herrera R, Carvajal-Rodríguez L, Reynés-Manzur J, García-Piña C, Barrios-Fuentes R, y cols: Enfermedad de Kawasaki. Acta Pediatr Mex 2001; 22(2): 97-103.
Sotelo-Cruz N, González-Ramos LA, Gómez-Rivera N, Manzo-Ríos MA: Enfermedad de Kawasaki. Experiencia en siete niños. Rev Mex Pediatr 2001; 68(5): 189-195.
Coronel-Rodríguez W, Tello GI, Erdmenger-Orellana J, Coria-Lorenzo JJ, Gómez-Barreto D: Síndrome de Kawasaki. paciente de menor edad reportado en la casuística del Hospital Infantil de México Federico Gómez y revisión de la literatura. Bol Med Hosp Infant Mex 2002; 59: 430-435.
Frenkel-Salaman M, Ocaña-García LA, Bautista-Santos A, Cortina-Ramírez M, Cortina-Watson J: Enfermedad de Kawasaki. Experiencia en ocho casos del Centro Médico ABC. An Med Asoc Med Hosp ABC 2004; 49(2): 66-72.
Castillo-Machado R, Coria-Lorenzo JJ, Espinoza-Oliva M, Gómez-Barreto D: Síndrome de Kawasaki asociado a infección por Streptococcus pyogenes. Informe de un caso y revisión de la literatura. Alerg Asma Inmunol Pediatr 1999; 8(4): 105-108.
Cervantes-Salazar JL, Calderón-Colmenero J, García-Montes JA, Patiño-Bahena E, González-Pacheco H, Soule-Egea M, Ramírez-Marroquín S: Enfermedad de Kawasaki, conceptos sobre la cirugía de resvascularización coronaria en edad pediátrica. Arch Cardiol Mex 2006; 76: 75-79.
Meissner HC, Leung DY: Kawasaki syndrome. Where are the answers? Pediatrics 2003; 112: 672-675.
Meissner HC, Leung DY: Superantigens, conventional antigen and the etiology of Kawasaki syndrome. Pediatr Infect Dis J 2000; 19: 91-94.
Susuki H, Noda E, Miyawaki M, Takeuchi T, Vemura S, Koike M: Serum levels of neutrophil activation cytokines in Kawasaki disease. Pediatr Int 2001: 43: 115-119.
Sohn MH, Noh SY, Chang W, Shin KM, Kim DS: Circulating interleukin 17 is increased in the acute stage of Kawasaki disease. Scand J Rheumatol 2003; 32: 364-366.
Aviña-Fierro JA, López-Bautista R, Toro-Castro L: Bases inmunológicas actuales de la enfermedad de Kawasaki. Alerg Asma Inmunol Pediatr 2004; 13(3): 104-108.
Rodríguez-Pla A, Stone JH: Vasculitis and infections. Curr Opin Rheumatol 2006; 18: 39-47.
Kato H. Sugimura T, Agaki N, Sato N, Hashino K, Maeno Y, et al: Long term consequences of Kawasaki disease at 10 to 21 years. Follow up study of 594 patients. Circulation 1996; 89: 919-922.
Yanagawa H, Nakamura Y, Yashiro M, Oki T, Hirata SH, Zhang T, Kawasaki T. Incidence survey of Kawasaki disease in 1977-1998 in Japan. Pediatrics 2001; 107(3): p.e. 33.
González-Galanares M, Urban-Vázquez H, Santamaría-Díaz M, Garbea-Robles MC: Enfermedad de Kawasaki en México. Análisis de 13 casos. Bol Med Hosp Infant Mex 1991; 48: 409-446.
Alva-Espinoza C, Díaz-Aranzo A, Mojarra-Ríos TA, Jiménez-Zepeda D: Enfermedad de Kawasaki. Diagnóstico ecocardiográfico de los aneurismas coronarios. Informe de dos casos. Arch Inst Cardiol Mex 1995; 65: 73-75.
Vargas JB, Andrade AF: Diagnósticos de ecocardiografía bidimensional Doppler de aneurismas coronarios en un niño mexicano con enfermedad de Kawasaki. Arch Inst Cardiol Mex 1988; 58: 227-229.
Rodríguez-Herrera R, Carbajal-Rodríguez L, Reynes-Manzur J, Mora-Tiscareño A, Zarco-Román J: Enfermedad de Kawasaki complicada con aneurismas gigantes e infarto del miocardio. Informe de un caso. Acta Pediatr Mex 2006; 27: 128-132.
Maya Enero S, Cols Roig M, Ros Veladoms JB, Pou Fernández J: Kawasaki disease in a 3 month old infant. Ann Pediatr (Barc) 2004; 61: 271-272.
Bhatt M, Anil SR, Silverkumar K, Kumar K: Neonatal Kawasaki disease. Indian J Pediatr 2004; 71: 353-354.
Rauch AM, Glode MP, Wiggins JW, Rodríguez JG, Hopkins RS, Hurtwitz ES, et al: Outbreak of Kawasaki syndrome in Denver, Colorado. Association with rug and carpet cleaning. Pediatrics 1991; 87: 663-669.
Horita N, Yokota S, Fuse S, Takamuro M, Tomita H, Sato K, et al: The throat flora and its mytogenic activity in patients with Kawasaki disease. Mycobiol Immunol 2004; 48: 899-903.
Merlin E, AL Fatuhi H, Crost P: Kawasaki syndrome and Mycoplasma pneumoniae infection. Arch Pediatr 2004; 11: 972-973.
Shulman ST, Rowly AH: Advances in Kawasaki disease. Eur J Pediatr 2004; 163: 289-291.
Rodríguez Herrera R, Carbajal-Rodríguez L, Reynés-Manzur J, Barrios-Fuentes R, Zarco-Román J: Abordaje diagnóstico y terapéutico de la enfermedad de Kawasaki. Acta Pediatr Mex 2006; 27(1): 36-49.
Freeman A, Crawford S, Finn L, López AJ, Ferrando MS, Pérez TD, et al: Inflammatory pulmonary nodules in Kawasaki disease. Pediatr Pulmonol 2003; 36: 102-106.
Muta H, Isihii M, Sakaue T, Egami K, Furui J, Sugahara Y, et al: Older age is a risk factor for the development cardiovascular sequelae in Kawasaki disease. Pediatrics 2004; 114: 751-754.
Mavrogeni S, Papadopulos G, Douskou M, Kaklis S, Seimenis I, Baras P, et al: Magnetic resonance angiography is equivalent to X-ray coronary angiography for the evaluation of coronary arteries in Kawasaki disease. J Am Coll Cardiol 2004; 43: 649-652.
Endoh H, Tsukano S, Ishikawa Y, Takamuro M, Tsuda E, Ono Y, et al: Usefulness of electron beam computed tomography for quantitative estimation of myocardial ischemia in patients. Pediatr Int 2004; 46: 704-710.
Williams RV, Wilke VM, Tani LY, et al: Does Abciximab enhance regression of coronary aneurysm resulting from Kawasaki disease. Pediatrics 2002; 109(1): E 4.
Freeman AF, Shulman ST: Refractory Kawasaki disease. Pediatr Infect Dis J 2004; 23: 463-464.
Basta M, Fries LF: Atención del daño inmunitario provocado por complemento mediante inmunoglobulina intravenosa En: Rewold E, Morell A, eds. Inmodulación mediante inmunoglobulinas intravenosa. New York USA. Ed. Parthenon Publishing Group Pearl River, 1992; 47-61.
Wallace CA, French JW, Kahan SJ, Sherry DD: Initial intravenous gamma globulin treatment in Kawasaki disease. Pediatrcs 2000; 105: p.e.78.
Consejo de Salubridad General: Cuadro básico. Catálogo de medicamentos. 2ª ed. 1999, p. 23-28.