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Academia Mexicana de Neurología, A.C.

2006, Number 2

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Rev Mex Neuroci 2006; 7 (2)

Transient ischemic attack II. It predicts the ictus and protects the brain

Fernández CO

Language: Spanish
References: 26
Page: 142-146
PDF size: 70.17 Kb.


ABSTRACT

The clinical importance of the transient ischemic attacks (TIA) lies in the fact that it is the first manifestation of a cerebrovascular disease in quite a few patients. That is why the identification, etiological evaluation and adequate treatment can prevent an ictus occurrence and its human and social consequences. According to some studies, between 10 and 17% of the patients who suffer a TIA will have a cerebral infarction within the next 90 days (three months); meanwhile between 8 and 12% of other patients will have it in the next 30 days (one month). These studies on early risk clearly prove that the time window to prevent an ictus is very short for individuals who suffered a TIA and it represents an element which supports the concept for a fast action in its etiology definition and the adoption of the most suitable treatment as the current outlines recommend for it. On the other side, there are literature reports referring to studies with animal models which have shown that for short periods of global or focal cerebral ischemia they can have a protective effect against permanent cerebral ischemia future episodes; this protection is a transient phenomenon and depends on the number of the TIA; the mechanisms that explain this tolerance to the ischemia seem to be related with changes in physiology and neuronal biochemistry.


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