2004, Number 4
Next >>
Acta Med 2004; 2 (4)
Infantile acute gastroenteritis due to human rotavirus. Epidemiological study at the Angeles Hospital-Pedregal
Pigeon-Oliveros H
Language: Spanish
References: 21
Page: 219-225
PDF size: 100.32 Kb.
ABSTRACT
In a prospective-descriptive epidemiological study it is informed that in eutrophic
children from 3 months to 5 years of age, with a clinical diagnosis of acute infectious
gastroenteritis (GA), from 1
st of January to the 30
th of June of
2002, ambulatory and hospitalized for secondary dehydration.
Objectives:
Investigate the annual frequency and the monthly incidence, in ambulatory and hospitalized
patients with GA caused by human rotavirus (RVH). The incidence of RVH in patients younger
than 2 years of age hospitalized, and the sever ness of GA in hospitalized children with a
dehydration degree of 10% more than there admittance in 67 patients (7%) all younger age
two years.
Material and methods: 3,295 children with infectious GA were studied;
2,345 (71%) external, and 950 (29%) hospitalized with GA for secondary dehydration.
RVH was identified in excretions by monoclonal antibody (rotatest kit).
Results
: In four years (1999-2002) in 2,345 external patients with GA, RVH was identified in 789
samples (33.6%). In 950 hospitalized children the result was positive in 402 (42.32%). The
annual frequency of RVH in 3,295 ambulatory and hospitalized children with GA was positive
in 1,191 excretion samples (36.15%). The higher monthly incidence in both groups was in
winter. In 402 children with GA-RVH hospitalized for secondary dehydration; 350 children
(87%) were younger than 2 years of age. The highest severity estimated by the degree of
dehydration at their admittance was: severe 10% or more in 67 children (7%) all of them
younger than 2 years of age. There were no demises. Conclusions: We didn’t observe in four
years any variations in the annual frequency of GA-RVH in ambulatory and hospitalized
patients of less than 5 years of age. The incidence for GA-RVH is higher in winter in
children of less than 2 years old. The severity for dehydration occurs in children of less
than 2 years old. The clinical antecedent of GA-RVH was investigated in all the cases of
hospitalized patients, and the result was negative. A prevalent seropositive type is
possible.
REFERENCES
World Health Organization. Rotavirus and other viral diarrhea. Report a subgroup of scientific working on epidemiology and etiology. Bull WHO 1980; 58: 183.
Snyder JD, Merson MH. The magnitude of the global problem of acute diarrhoeal disease; a review of active surveillance data. Bull WHO 1982; 60: 605-613.
Muñoz HO, Alvarez MT. Diarrea por rotavirus. Enfermedades diarreicas en el niño. 9a ed. México. 1992: 207-215.
Kumate J. Panorama epidemiológico de las diarreas en México. En: Mota-Hernandez F, Velásquez-Jones L, UNICEF/OPS/Hospital Infantil de México Federico Gomez. México. 1985: 4-14.
Pickering LK, Evans DF, Muños O. Prospective studies of enteropathogens in children with diarrhea in Houston and México. J Pediatr 1978; 93: 383.
Calderón JE, Espejo R, González N, Hernández M, Romero P. Maulen: Aspectos epidemiológicos de la gastroenteritis aguda producida por rotavirus. Bol Med Hosp Infant Mex 1978; 35: 45-55.
Kumate J, Isibasi A. Pediatric diarrheal diseases: a global perspective. Pediatric Infect Dis 1986; 5: S21.
Biomerieux SA, Slidex Rota-kit 2. Francia 06/1996, num. 58842.
Espejo R, Calderon E. Rotavirus gastroenteritis in hospitalized infants and young children in México City. Rev Lat Am Microbiol 1978; 20: 239.
Espinoza-Larios EL. Colorado DJ. Frecuencia de gastroenteritis infecciosa aguda por rotavirus en niños de diversas poblaciones de la República Mexicana. Bol Med Hosp Infant Mex 1983; 40: 188-198.
Evans DG, Olarte J. Enteropathogens associated with diarrhea in México City. J Pediat 1977; 91: 65-68.
Cevallos PA, Pigeon OH. Gastroenteritis aguda en un hospital privado. Rev Mex Pediatr 2002; 69(2): 61-63.
Kapikian AZ, Chanock RM. Rotaviruses. In: Fields BN, ed: Virology. New York: Raven Press, 1985: 863-906.
Hamilton JR. Viral diarrhea. Pediatr Ann 1985; 14: 25.
Vega FL, Romo G, Velasco F, Peña R, Lira J. Sensibilidad y especificidad de la rotaforesis en el diagnóstico de la diarrea por rotavirus. 1984; 41: 656-660.
Espejo TR, Calderón E, Gonzalez N, Salomón A, Martuscelli A, Romero P. Prescence of two distinct types of rotavirus in infants and young children hospitalized with acute gastroenteritis in México City. J Infect Dis 1979; 139: 474-477.
Brandt CD, Kim HW, Rodriguez WJ. Adenoviruses and pediatric gastroenteritis. J infect Dis 1985; 151: 437.
Dupont HL. Rotaviral gastroenteritis some recent developments. J Infect Dis 1984; 149: 663.
Hernández-Henríquez H, Pérez S, Soto-Escalona A. Estudio seroepidemiológico de rotavirus en una población infantil venezolana. Relación entre lactancia materna y seropositividad. Bol Med Hosp Infant Mex 1984; 41: 580-584.
Morbidity and mortality Weekly report, recommendations of the advisory Committee on Immunization Practices. CDC 1999; 48: 2-23.
Rotavirus vaccine. Advisory Committee on Immunization Practices. CDC 1998, Julio 1999.