Language: Spanish
References: 94
Page: 66-74
PDF size: 85.64 Kb.
ABSTRACT
One current problem in Public Health relates to suicide and the identification of the risk factors needs to be clarified accurately. The bases of suicide involve complex multiple factors. In a high proportion of nations, mainly in industry-developing countries, suicide is placed among the first three causes of death in groups aged from 15 to 34 years. In Mexico, suicide represents the ninth cause of mortality, within a wide scale of age ranging from 15 to 64 years.
Some risk factors have been identified. Epidemiological studies show that males commit suicide more frequently than females, in a proportion of 5:1. Consummate suicide occurs in men about 50 years old, mainly by hanging or fire arms. Females between 20 and 29 years old, on the contrary, carry out more frequent unsuccessful attempts in the same proportion, by using pesticides and medical drugs. However, in recent years an increase in the number of suicides among young people from 15 to 24 years old has been observed, commonly in low-income sectors, in subjects with a previous history of psychiatric disorders, mainly personality disorders, abuse of substances and prior suicidal attempts. The risk of suicide generally increases after 45, and becomes especially serious in older people. The phenomenon of suicide in the elderly deserves special attention, due to the fact that the population over 65 years old is continuously increasing. This group displays fewer attempts than youths, but they achieve their aim more often through a silent suicide, by refusing to eat or to accept and follow medical prescriptions.
Some psychiatric disturbances are intimately related to suicide. It is considered that 50% or more of the consummate suicides are performed by people suffering from an affective disorder, mainly depression. In this sense, it is noteworthy that most of these patients had been misdiagnosed and in many cases had not received any proper treatment. In addition, the abuse of or dependence on alcohol is present in about 20% of consummate suicides, and high rates of suicide are also observed in schizophrenia.
Another common disturbance associated with suicide is anxiety. The simultaneous presence of anxiety and depression must be considered as a great risk factor, since the depressed patient has a high risk of committing suicide under phases of increased anxiety. All of these observations imply an alert signal for medical care units concerning the importance of detecting signs of the presence of risk factors and suicidal ideation, and of implementing adequate therapeutic management, namely, a supervised pharmacological treatment of depression and anxiety, including hospitalization, if it were the case.
The risk factors in potential suicide include isolation, poor health, depression, alcoholism, lowered self-esteem, despair and feelings of social and family refusal. Frequently, the potential suicide directly or indirectly gives behavioral and verbal cues of his or her suicidal intention. Roughly, 60% of the victims of suicide had attended some medical care unit in the month previous to the suicide and had commented something about their desires and feelings about death at some moment, and 30% had clearly revealed their suicidal ideation. For such reason, the evaluation of risk of the potentially suicidal patient should be a common practice in medical care units. Therefore, the early detection of the presence of risk factors of suicide, including the report of self-harm and of a detectable incapacity for solving problems, mainly of social type may provide an invaluable time to permit its prevention.
Another current aspect awaiting conclusive evidence is associated with some controversial data regarding the impact that the use of antidepressants could have upon suicide. The Food and Drug Administration office (USA) pointed out that deficiencies in information do not allow to confirm any existing relation between the use of serotonin selective reuptake inhibitors (SSRIs) and suicide in youths. The suicidal risk after initiating the treatment is similar in the patient receiving tricyclics, or serotonin selective reuptake inhibitors. The risk of suicide can increase significantly in the first month of antidepressant treatment, especially during the first nine days. Consequently, the observation that patients receiving antidepressants attempt suicide, is due, at least partly, to the fact that for still unknown reasons, antidepressants require from three to four weeks of impregnation to attain clear therapeutic effects.
Therefore, it is indispensable to carry out further clinical and experimental studies to determine the variables that could be implied in this time lag in the action of antidepressants. However, fluoxetine represents a useful alternative in the management of depressive disorders; albeit as in the case of other antidepressants, it requires a strict follow-up of the patient receiving such treatments to avoid the risk of a fatal complication.
In conclusion, the suicide risk, being a serious problem of public health, requires special attention. Recent research indicates that the prevention of suicide includes a series of activities, such as educational programs for children and youths, teachers and educators, and also primary health care units for the early detection of suicide risk factors. And, of course, medical training for the management of the potential suicide.
For all of them, some relevant facts must be taken into account:
1) Depression can be present in children and adolescents.
2) Access to means of committing suicide, such as weapons, must be avoided.
3) People from medical care units should be on the alert when any one shows signs and symptoms of despair and impulsiveness.
4) Suicide, anxiety and depression have a biological basis; therefore it is not a matter of cowardice or an act of defiance.
5) An inadequate and inopportune diagnosis may increase the suicidal risk.
6) Parents and teachers should be instructed to detect any sign of suicidal ideation and despair. Therefore, this revision intends to bring some recent data to bear upon the factors of the risk of suicide that provide the reader with information for a more effective prevention.
REFERENCES
AGÜERA LF: ¿Cuál es la relación entre depresión y suicidio en el anciano? En: Calcedo A (ed). La Depresión en el Anciano. Doce Cuestiones Fundamentales. Fundación Archivos de Neurobiología, 181-202, Madrid, 1996.
AHRENS B, LINDEN M: Suicidal behavior-symptom or disorder? Comprehensive Psychiatry, 41(Supl.1):116-121, 2000.
ANTRETTER E, DUNKEL D, SEIBL R, HARING C: Classification and predictive quality of the "suicide intent" marker in parasuicides. A cluster analytic study. Nervenarzt 73(3):219-230, 2002.
BARAK Y, MIRECKI I, KNOBLER HY, NATAN Z, AIZENBERG D: Suicidality and second generation antipsychotics in schizophrenia patients: a case-controlled retrospective study during a 5-year period. Psychopharmacology, 175(2):215-219, 2004.
BARTELS SJ, COAKLEY E, OXMAN TE, CONSTANTINO G y cols.: Suicidal and death ideation in older primary care patients with depression, anxiety, and at-risk alcohol use. Am J Geriatr Psychiatry, 10(4):417-427, 2002.
BECERRA B, PAEZ F, ROBLES-GARCIA R, VELA GE: Temperament and character profile of persons with suicide attempt. Actas Esp Psiquiatr, 33(2):117-122, 2005.
BECK AT, WEISSMAN A, LESTER D, TRECLER L: The measurement of pessimism: the hopelessness Scale. J Consult Clin Psychol, 42:861-865, 1974.
BECK AT, WEISSMAN A, LESTER D, TREXLER L: Classification of suicidal behavior. II Dimensions of suicidal intent. Arch Gen Psychiatry, 33:835-837, 1976.
BECK AT: Thinking and depression, I: idiosyncratic content and cognitive distortions. Arch Gen Psychiatry, 9:324-335, 1963.
BERTOLOTE JM, FLEISCHMANN A, DE LEO D, WASSERMAN D: Suicide and mental disorders: do we know enough? British J Psychiatry, 183:382-383, 2003.
BOERGERS J, SPIRITO A, DONALDSON D: Reasons for adolescent suicide attempts: associations with psychological functioning. J Am Acad Child Adolesc Psychiatry, 37(12):1287-1293, 2000.
BORGES G, CHERPITEL CJ, MACDONALD S, GIESBRECHT N, STOCKWELL T, WILCOX HC: A case-crossover study of acute alcohol use and suicide attempt. J Stud Alcohol, 65(6):708-714, 2004.
BORGES G, SALTIJERAL MT, BIMBELA A, MONDRAGON L: Suicide attempts in a simple of patients from a General Hospital. Arch Med Res, 31(4): 366-372, 2000.
BORGES G, WALTERS EE, KESSLER RC: Associations of substance use, abuse, and dependence with subsequent suicidal behavior. Am J Epidemiol, 151(8):781-789, 2000.
CALDERON-NARVAEZ G: Depresión. Causas, Manifestaciones y Tratamiento. Trillas, México, 1985.
CARAVEO-ANDUANGA J, COMENARES E, SALDIVAR G: Estudio clínico-epidemiológico de los trastornos depresivos. Salud Mental, 22(2):7-17, 1999.
CATALDO-NETO A, MORELLI LB, MENEZES F: Paciente suicida. En: Fritscher CC, Chatkin JM, Wainstein R (eds). Manual de Urgencias Médicas. Epipucrs, Porto Alegre, 509-515, 2002.
CHEN YW, DILSAVER SC: Lifetime rates of suicide attempts among subjects with bipolar and unipolar disorders relative to subjects with other Axis I disorders. Biol Psychiatry, 39(10):896-899, 1996.
CHIOQUETA AP, STILES TC: Suicide risk in outpatients with specific mood and anxiety disorders. Crisis, 24(3):105-112, 2003.
CONTRERAS CM, RODRIGUEZ-LANDA JF, GUTIERREZ-GARCIA AG, BERNAL-MORALES B, SAAVEDRA M: Estudio experimental de la ansiedad y la depresión. Ciencia, 54(2):29-39, 2003.
DOGGRELL SA: Fluoxetine-do the benefits outweigh the risk in adolescent major depression? Expert Opin Pharmacother, 6(1):147-150, 2005.
DOMENECH JR: Enfermedad médica y suicidio. En: Ros S (ed). La Conducta Suicida. Libro de Año SL, 161-178, Madrid, 1997.
DOUGHERTY DM, MATHIAS CW, MARSH DM, MOELLER FG, SWANN AC: Suicidal behaviors and drug abuse: impulsivity and its assessment. Drug Alcohol Depend, 76:S93-S105, 2004.
DUMAN RS, HENINGER GR, NESTLER EJ: A molecular and cellular theory of depression. Arch Gen Psychiat, 54:597-606, 1997.
EVANS E, HAWTON K, RODHAM K, DEEKS J: The prevalence of suicidal phenomena in adolescents: a systematic review of population-bases studies. Suicide Life Threat Behav, 35(3):239-250, 2005.
FORSTER PL, WU LH: Assessment and treatment of suicidal patients in an emergency setting. Rev Psychiatry, 21:75-113, 2002.
FOSTER T: Suicide note themes and suicide prevention. Int J Psychiatry Med, 33(4):323-331, 2003.
FRANKO DL, KEEL PK, DORER DJ, BLAIS MA y cols.: What predicts suicide attempts in women with eating disorders? Psychol Med, 34(5):843-853, 2004.
GINSBERG DL, SCHOOLER NR, BUCKELY PF, HARVEY PD, WEIDEN PJ: Optimizing treatment of schizophrenia. Enhancing affective/cognitive and depressive functioning. CNS Spectr, 10(2):1-13, 2005.
GOLDNEY RD: Suicide prevention: a pragmatic review of recent studies. Crisis, 26(3):128-140, 2005.
GONZALEZ-FORTEZA C, VELAZQUEZ JV, ESCALERA IA: Attempted suicide prevalence in adolescent students of Mexico City 1997-2000. Salud Mental, 25(6):1-12,2002.
GOODWIN FK: Preventing inpatient suicide. J Clin Psychiatry, 64(1):13-13, 2003.
GUCCIARDI E, CELASUN N, AHMAD F, STEWART DE: Eating disorders. BMC Womens Health, 4(Supl.1):S21, 2004.
GUTIERREZ-ALANIS T, LARA-MORALES H, CONTRERAS CM: Aplicación del Children's Depression Scale a una muestra de niños sanos de instrucción primaria en la ciudad de México. Salud Mental, 18:51-54, 1995.
HARVAKY-FRIEDMAN JM, NELSON EA, VENARDE DF, MANN JJ: Suicidal behavior in schizophrenia and schizoaffective disorder: examining the role of depression. Suicide Life Threat Behav, 34(1):66-76, 2004.
HEALY D, WHITAKER C: Antidepressants and suicide: riskbenefit conundrums. J Psychiatry Neurosci, 28(5):331-337, 2003.
HIJAR M, D CHU L, KRAUS JF: Cross-national comparison of injury mortality: Los Angeles country, California and Mexico City, Mexico. International J Epidiomiol, 29:715-721, 2000.
HIJAR M, RASCON RA, BLANCO J, LOPEZ MA: Los suicidios en México. Características sexuales y geográficas (1979- 1993). Salud Mental, 19(4):14-21, 1996.
INSKIP HM, HARRIS EC, BARRACLOUGH B: Lifetime risk of suicide for affective disorder, alcoholism and schizophrenia. Br J Psychiatry, 172:35-37, 1998.
INSTITUTO NACIONAL DE ESTADISTICA, GEOGRAFIA E INFORMATICA: Estadística de Intentos de Suicidio y Suicidios. Cuaderno 8:20-25, México,2002.
ISACSSON G: Suicide prevention -a medical break through? Acta Psychiatr Scand, 102:113-117, 2002.
JICK H, KAYE JA, JICK SS: Antidepressants and the risk of suicidal behaviors. JAMA, 292(3):338-343, 2004.
JIMENEZ-GENCHI A, IBARRA-ALCANTAR C, PEÑALOSA-GARCIA L, DIAZ-GALVIS JL: El suicidio en instituciones psiquiátricas: descripción de dos casos. MedUNAB, 7:140-143, 2004.
JOINER TE, BROWN JS, WINGATE LR: The psychology and neurobiology of suicidal behavior. Annu Rev Psychol, 56:287-314, 2005.
KANE RL, OUSLANDER JG, ABRASS IB: Geriatría Clínica. Tercera edición. McGraw-Hill Interamericana, México, 1997.
KHAN A, KHAN S, KOLTS R, BROWN WA: Suicide rates in clinical trials of SSRIs, other antidepressants, and placebo: analysis of FDA reports. Am J Psychiatry, 160(4):790-792, 2003.
KHAN A, LEVENTHAL RM, KHAN S, BROWN WA: Suicide risk in patients with anxiety disorders: a meta-analysis of FDA database. J Affect Disord, 68(2-3):183-190, 2002.
KOHLBERG L: Continuities in childhood and adult moral development revisited. En: Baltes PB, Shaire KW (eds). Life Span Development Psychology: Personality and Socialization. Academic Pres, Nueva York, 1973.
KOLLER G, PREUSS UW, BOTTLENDER M, WENZEL K, SOYKA M: Impulsivity and aggression as predictors of suicide attempts in alcoholics. Eur Arch Psychiatry Clin Neurosci, 252(4):155-160, 2002.
LAPIERRE YD: Suicidality with selective serotonin reuptake inhibitors: valid claim? Rev Psychiatr Neurosci, 28(5):340-347, 2003.
MANN JJ, APTER A, BERTOLOTE J, BEAUTRAIS A y cols.: Suicide prevention strategies. A systematic Review. JAMA, 294(16):2064-2074, 2005.
MANN JJ, BORTINGER J, OQUENDO MA, CURRIER D y cols.: Family history of suicidal behavior and mood disorders in probands with mood disorders. Am J Psychiatry, 162(9):1672-9, 2005.
MANN JJ, WATERNAUX C, HAAS GL, MALONE KM: Toward a clinical model of suicidal behavior in psychiatric patients. Am J Psychiatry, 156:181-189, 1999.
MANN JJ: Neurobiology of suicidal behavior. Nat Rev Neurosci, 4(10):819-828, 2003.
MANN JJ: Searching for triggers of suicidal behavior. Am J Psychiatry, 161:395-397, 2004.
MANN JJ: The neurobiology of suicide. Nat Med, 4(1):25-30, 1998.
MARCH J, SILVA S, PETRYCKI S, CURRY J y cols.: Fluoxetine, cognitive-behavioral therapy, and their combination for adolescents with depression: Treatment for adolescents with depression study (TADS) randomized controlled trial. JAMA, 292(7)807-820, 2004.
MARIS RW: Suicide. Lancet, 360:319-326, 2002.
MARTINEZ-MEDINA MP. Debate sobre el uso de inhibidores selectivos de recaptura de serotonina en niños y adolescentes. Instituto Nacional de Psiquiatría Ramón de la Fuente.Información Clínica, 15(6):31-36, 2004.
MELGES FT, BOWLBY J: Types of hopelessness in psychopathological process. Arch Gen Psychiatry, 20(6):690-699, 1969.
MOLNAR BE, BERKMAN LF, BUKA SL: Psychopathology, childhood sexual abuse and other childhood adversities: relative links to subsequent suicidal behaviour in the US. Psychol Med, 31(6):965-77, 2001.
MURPHY GE, WETZEL RD, ROBINS E, MCEVOY L: Multiple risk factors predict suicide in alcoholism. Arch Gen Psychiatry, 49(6): 459-463, 1992.
ORGANIZACION MUNDIAL DE LA SALUD: Guías para el Diseño, Implementación y Evaluación de Sistemas de Vigilancia Epidemiológica de Lesiones. OMS, Ginebra, 2004.
ORGANIZACION MUNDIAL DE LA SALUD: Informe Mundial sobre la Violencia y la Salud. OMS, Ginebra, 2002.
OVERMIER JB: On learned Helplessness. Int Physiol Behav Sci, 37(1):4-8, 2002.
PALMONARI A: Psicologia dell´Adolescenza. Mulino, Bolonia, 1993.
PAPALIA DE, WENDKOS-OLDS S, FELDMAN RD: Desarrollo Humano. Novena edición. McGraw-Hill, México, 2004.
PIAGET J: La Representación del Mundo en el Niño. Fontanella, Barcelona, 1971.
POMPILI M, MANCINELLI I, GIRARDI P, RUBERTO A, TATARELLI R: Suicide in anorexia nervosa: a meta-analysis. Int J Eat Disord, 36(1):99-103, 2004.
POST RM: The impact of bipolar depression. J Clin Psychiatry, 66(Suppl.5):5-10, 2005.
PUENTES-ROSAS E, LOPEZ-NIETO L, MARTINEZMONROY T: Mortality from suicides: México, 1990-2001. Rev Panam Salud Pública, 16(2):102-109, 2004.
RADOMSKY ED, HAAS GL, MANN JJ, SWEENEY JA: Suicidal behavior in patients with schizophrenia and other psychotic disorders. Am J Psychiatry, 156(10):1590-1595, 1999.
ROCA M, BERNARDO M: Depresión y enfermedad médica. En: Roca M, Bernardo M (eds). Trastornos Depresivos en Patologías Médicas. Masson, 1-13, Barcelona, 1996.
ROSSI A, BARRACO A, DONDA P: Fluoxetine: a review on evidence based medicine. Ann Gen Hosp Psychiatry, 3(1):1-8, 2004.
ROY A, DRAPER R: Suicide among psychiatric hospital impatients. Psychol Med, 25:199-202, 1995.
ROY A, SEGAL NL, CENTERWALL BS, ROBINETTE CD: Suicide in twins. Arch Gen Psychiat, 48:29-32, 1991.
ROY A, SEGAL NL: Suicidal behavior in twins: a replication. J Affect Disord, 66(1):71-74, 2001.
ROY A: Family history of suicide. Arch Gen Psychiatry, 40:971-974, 1983.
ROY A: Psychiatric emergencies. En: Kaplan HI, Sadock BJ (eds). Sinopsis of Psychiatry, Octava edición. Artes Médicas, 864-872, Porto Alegre, 1997.
RUUSKA J, KALTIALA-HEINO R, RANTANEN P, KOIVISTO AM: Psychopathological distress predicts suicidal ideation and self-harm in adolescent eating disorder outpatients. Eur Child Adolesc Psychiatry, 14(5):276-281, 2005.
SANTA EE, GALLOP RM: Childhood sexual and physical abuse and adult self-harm and suicidal behaviour: a literature review. Can J Psychiatry, 43(8):793-800, 1998.
SCHNYDER U, VALACH L, BICHSEL K, MICHEL K: Attempted suicide. Do we understand the patients´reasons? Gen Hosp Psychiatry, 21(1):62-69, 1999.
SCHULSINGER F, KETY SS, ROSENTHAL D, WENDER PH: A family study of suicide. En: Shou M, Stromgren E (eds). Origin, Prevention, and Treatment of Affective Disorder. Academic Press, 277-287, Nueva York, 1979.
SELIGMAN ME: Helplessnes on Development, Depression and Death. Freeman and Company, Nueva York, 1975.
SHARMA V: Atypical antipsychotics and suicide in mood and anxiety disorders. Bipolar Disord, 5(Supl.2):48-52, 2003.
SKEGG K: Self-harm. Lancet, 366(9495):1471-1483, 2005.
SPECKENS AE, HAWTON K: Social problem solving in adolescents with suicidal behavior: a systematic review. Suicide Life Threat Behav, 35(4):365-387, 2005.
STATHAM DJ, HEATH AC, MADDEN PAF, BUCHOLZ KK y cols.: Suicidal behaviour: an epidemiological and genetic study. Psychol Med, 28:839-855, 1998.
SUOMINEN K, ISOMETSA E, HENRIKSSON M, OSTAMO A, LONNQVIST J: Hopelessness, impusiveness and intent among suicide attempters with major depression, alcohol dependence, or both. Acta Psychiatr Scand, 96(2):142-149, 1997.
TANDON R: Suicidal behavior in schizophrenia. Expert Rev Neurother, 5(1):95-99, 2005.
TEICHER MH, GLOD C, COLE JO: Emergence of intense suicidal preoccupation during fluoxetine treatment. Am J Psychiatry, 147:207-210, 1990.
VAN HEERINGEN K: The neurobiology of suicide and suicidality. Can J Psychiatry, 48(5):292-300, 2003.
WONG IC, BESAG FM, SANTOSH PJ, MURRAY ML: Use of selective serotonin reuptake inhibitors in children and adolescents. Drug Saf, 27(13):991-1000, 2004.
YAP HK: Assessment of suicide risk. Singapore Med J, 34(2):164-166, 1993.