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2007, Number 3

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Rev Inst Nal Enf Resp Mex 2007; 20 (3)

Genetic polymorphisms: Significance and applications

Checa CMA

Language: Spanish
References: 52
Page: 213-221
PDF size: 94.96 Kb.


ABSTRACT

About 99.9% of the DNA sequences of two different individuals are identical. A significant amount of the differences among individuals, that is, phenotypic differences and those responsible for susceptibility to pathology, lie within that variation of 0.1%. These genetic variations are known as genetic polymorphisms, representing differences in the sequences of DNA. The study of these variations in the areas of biology and evolution can provide information for different applications in medicine. Therefore, the objective of the present review is to describe the different types of genetic variations present in the human genome as well as their importance and possible applications in medicine.


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