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2007, Número 3

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Rev Inst Nal Enf Resp Mex 2007; 20 (3)


Polimorfismos genéticos: Importancia y aplicaciones

Checa CMA

Idioma: Español
Referencias bibliográficas: 52
Paginas: 213-221
Archivo PDF: 94.96 Kb.


RESUMEN

Aproximadamente el 99.9% de la secuencia del ADN de dos individuos diferentes es la misma. Una proporción significativa de las diferencias encontradas en los individuos, es decir, sus diferencias fenotípicas y/o susceptibilidades a ciertas enfermedades, radica en el 0.1% de variación; a este tipo de variaciones genéticas se les conoce como polimorfismos genéticos, los cuales representan diferentes formas en las secuencias de ADN. El estudio de estas variaciones tiene diversas aplicaciones en el campo de la medicina así como en el desarrollo de investigaciones biológicas y de evolución. Esta revisión describe los diferentes tipos de variaciones genéticas que presenta el genoma humano, así como su importancia y posible aplicación en la medicina.


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