2007, Number 3
<< Back Next >>
Acta Med 2007; 5 (3)
Cholinergic urticaria induced by exercise
Domínguez CLG, Arellano AJG
Language: Spanish
References: 41
Page: 149-152
PDF size: 77.46 Kb.
ABSTRACT
Cholinergic urticaria induced by exercise is manifested by 2 to 4 mm punctuate papules and/or pruritic macular erythema; it can be followed by dyspnea, angioedema and hypotension. Since the original case description in 1979, more than 1,000 cases have been described in the literature. It is frequently in young people under 40’ years old, and its presentation is similar in males and females. Prevalence has a range from 0.2 to 0.7%.The specific etiology of exercise-induced cholinergic urticaria is unclear. It is likely that vasoactive mediators released by mast cells degranulation are responsible for the symptoms and an increase in plasma histamine levels and tryptase has been demonstrated. The lesions are known to occur during 2 to 20 minutes of exercise; Antihistamines drugs are partially effective in preventing exercise-induced anaphylaxis. Modification of activities and behaviors is the mainstay of treatment in patients with exercise-induced cholinergic urticaria. We present a 36 years old female case with this diagnosis.
REFERENCES
Pérez PA, Fernández PB, Santaolalla MM, Paz AS, Domínguez L. Síndrome de anafilaxia inducida por ejercicio. An Med Int 2001; 18: 269-273.
Volcheck GW, Li JT. Exercise-induced urticaria and anaphylaxis. Mayo Clin Proc 1997; 72: 140-147.
Kounis NG, MacMahon RG. Cholinergic urticaria with systemic manifestations. Ann Allergy 1975; 35: 243-245.
Lawrence CM, Jorizzo JL, Kobza-Black A et al. Cholinergic urticaria with associated angioedema. Br J Dermatol 1981; 105: 543-550.
Maulitz RM, Pratt DS, Schocket AL. Exercise-induced anaphylactic reaction to shellfish. J Allergy Clin Immunol 1979; 63: 433-434.
Novey HS, Fairshter RD, Salness K, Simon RA, Curd JG. Postprandial exercise-induced anaphylaxis. J Allergy Clin Immunol 1983; 71: 498-504.
Romano A, Di Fonso M, Giuffreda F et al. Diagnostic work-up for food-dependent, exercise-induced anaphylaxis. Allergy 1995; 50: 817-824.
Shadick NA, Liang MH, Partridge AJ et al. The natural history of exercise-induced anaphylaxis: survey results from a 10-year follow-up study. J Allergy Clin Immunol 1999; 104: 123-127.
Silvers WS. Exercise-induced allergies: the role of histamine release. Ann Allergy 1992; 68: 58-63.
Sheffer AL, Tong AKF, Murphy GF, Lewis RA, McFadden ER, Austen KF. Exercise-induced anaphylaxis: a serious form of physical allergy associated with mast-cell degranulation. J Allergy Clin Immunol 1985; 75: 479-484.
Schwartz HJ. Elevated serum tryptase in exercise-induced anaphylaxis. J Allergy Clin Immunol 1995; 95: 917-919.
Nichols AW. Exercise-induced anaphylaxis and urticaria. Clin Sports Med 1992; 11: 303-312.
Kidd JM, Cohen SH, Sosman AJ, Fink JN. Food-dependent exercise-induced anaphylaxis. J Allergy Clin Immunol 1983; 71: 407-411.
Briner WW Jr. Physical allergies and exercise. Clinical implications for those engaged in sports activities. Sports Med 1993; 15: 365-373.
Fujimoto S, Kurihara N, Hirata K, Kamimori T, Tanaka S, Takeda T. Successful prophylaxis of wheat-dependent exercise-induced anaphylaxis with terfenadine. Intern Med 1995; 34: 654-656.
Sheffer AL, Austen KF. Exercise-induced anaphylaxis. II. J Allergy Clin Immunol 1984; 73: 699-670.
Casale TB, Keahey TM, Kaliner M. Exercise-induced anaphylactic syndromes. Insights into diagnostic and pathophysiologic features. JAMA 1986; 255: 2049-2053.
Hirchman JV, Lawlar F, English JGC et al. Cholinergic urticaria. Arch Dermatol 1987; 123: 462-467.
Greenberger PA. Idiopathic anaphylaxis. Immunol Allergy Clinics North Am 1992; 12: 571-583.
Sheffer AL, Austen KF. Exercise-induced anaphylaxis. II. J Allergy Clin Immunol 1984; 73: 699-703.
Grant JA, Farnam J, Lord RA et al. Familial exercise-induced anaphylaxis. Ann Allergy 1985; 54: 35-38.
Longley S, Panush RS. Familial exercise-induced anaphylaxis. Ann Allergy 1987; 58: 257-259.
Dohi M, Suko M, Sugiyama H et al. Food-dependent, exercise-induced anaphylaxis: a study on 11 Japanese cases. J Allergy Clin Immunol 1991; 87: 34-40.
Lewis J, Lieberman P, Treadwell G, Erffmeyer J. Exercise-induced urticaria, angioedema, and anaphylactoid episodes. J Allergy Clin Immunol 1981; 68: 432-437.
Denzlinger C, Haberl C, Wilmanns W. Cysteinil leukotriene production in anaphylactic reactions. Int Arch Allergy Clin Immunol 1995; 108: 158-164.
Romano A, Fanales-Belasio E, Di Fonso M et al. Eosinophil-derived proteins in postprandial (food-dependent) exercise-induced anaphylaxis. Int Arch Allergy Immunol 1997; 113: 505-511.
Pauls JD, Cross D. Food-dependent exercise-induced anaphylaxis to corn. J Allergy Clin Immunol 1998; 101: 853-854.
Hernández J, Negro JM, Sellés JG et al. Urticaria y/o angioedema por ejercicio, dependiente de la ingestión de alimentos. Rev Esp Alergol Inmunol Clin 1992; 7: 9-17.
Martín MF, López CJM, Villas F, Contreras JF, Díaz JM, Ojeda JA. Exercise-induced anaphylactic reaction to hazelnut. Allergy 1994; 49: 314-316.
Stäger J, Wüthrich B, Johansson SGO. Spice allergy in celery-sensitive patients. Allergy 1991; 46: 475-478.
Okano M, Sakuma Y. Food-dependent exercise-induced anaphylaxis due to matsutake mushrooms. Br J Dermatol 1997; 1: 805.
McNeil D, Strauss RH. Exercise-induced anaphylaxis related to food intake. Ann Allergy 1988; 61: 440-442.
Asero R, Mistrello G, Roncarolo D, Antoniotti P, Falagiani P. Exercise-induced egg anaphylaxis. Allergy 1997; 52: 687-689.
Stäger J, Wüthrich B. Type I allergy to cow milk proteins in adults. A retrospective study of 34 adult milk and cheese allergic patients. Int Arch Allergy Immunol 1993; 102: 399-407.
Caffarelli C, Perone F, Terzi V. Exercise-induced anaphylaxis related to cuttlefish intake. Eur J Pediatr 1996; 155: 1025-1026.
Zondlo J, Muthiah R, Knoll R et al. Helicobacter pylori: a new cause of urticaria and exercise anaphylaxis. Identification of HP allergens (abstract). J Allergy Clin Immunol 1994; 93: 220.
Van Wijk RG, de Groot H, Bogaard JM. Drug-dependent exercise-induced anaphylaxis. Allergy 1995; 50: 992-994.
Katsunuma T, Iikura Y, Akasawa A, Iwasaki A, Hashimoto K, Akimoto K. Wheat-dependent exercise-induced anaphylaxis: inhibition by sodium bicarbonate. Ann Allergy 1992; 68: 184-188.
Lin RY, Barnard M. Skin test with food, codeine and histamine in exercise-induced anaphylaxis. Ann Allergy 1993; 70: 475-478.
Escudero PAI. Identificación, diagnóstico, prevención y tratamiento de las causas más frecuentes de anafilaxia recurrente. Rev Esp Alergol Inmunol Clin 1996; 11: 64-81.
Briner WW Jr. Physical allergies and exercise. Clinical implications for those engaged in sports activities. Sports Med 1993; 15: 365-373.