2007, Número 3
Urticaria colinérgica inducida por ejercicio
Domínguez CLG, Arellano AJG
Idioma: Español
Referencias bibliográficas: 41
Paginas: 149-152
Archivo PDF: 77.46 Kb.
RESUMEN
La urticaria colinérgica inducida por ejercicio se manifiesta por prurito y pápulas puntiformes de 2 a 4 mm de diámetro y/o eritema; puede acompañarse de disnea, angioedema e hipotensión. Descrita en 1979, se han reportado aproximadamente 1,000 casos en la literatura. Se presenta en jóvenes, desde la adolescencia hasta los 40 años, similar en ambos sexos. Su prevalencia varía de 0.2 a 0.7%. El mecanismo fisiopatogénico de UC implica la degranulación de mastocitos con elevación de los niveles de histamina plasmática y de otros mediadores como la triptasa sérica. El cuadro se manifiesta a los pocos minutos de iniciar el ejercicio. En general, los antihistamínicos son parcialmente efectivos para prevenir el episodio. En los casos en que no se logra evitar las reacciones, la alternativa es limitar la actividad física. Presentamos el caso de paciente femenino de 36 años con este diagnóstico.
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