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2007, Number 3

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Rev Mex Anest 2007; 30 (3)

Central venous saturation. Current concepts

Carrillo-Esper R, Núñez-Bacarreza JJ, Carrillo-Córdova JR

Language: Spanish
References: 26
Page: 165-171
PDF size: 503.68 Kb.


ABSTRACT

Tissue hypoperfusion contributes to the development of organ dysfunction. Consequently tissue perfusion should be monitored in patients at risk. Unfortunately, routinely monitored variables, such as blood pressure, heart rate, urine output, blood gases, or cardiac filling pressure, do not necessarily reflect the adequacy of tissue perfusion. Mixed venous oxygen saturation (SvO2) and central venous oxygen saturation (ScvO2) have been proposed as a better indicators of adequacy of oxygen supply. The normal range for SvcO2 which reflects the balance between systemic oxygen delivery (DO2) and demans, is about 75%. Monitoring of the mixed venous saturation is use as a surrogate for the balance between systemic oxygen delivery and consumption in the perioperative period. Readings may be taken intermittently by blood sampling and co-oximetry, or continuously with fiberoptic catheter; however, beneficial effects on patient outcome have been demonstrated so far only by continuous measurement. Since monitoring of SvcO2 looked promising in the experimental setting, several clinical studies including one large randomized trial have been performed in patients with different kinds of shock. This included patients with severe sepsis or septic shock, severe trauma, and cardiogenic shock.


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