Lazcano HE, Guerrero ME, Peña ME, Ramírez VA, Hernández ZR, Ávalos BA, Núñez Pérez-Redondo C

Language: Spanish
References: 25
Page: 106-112
PDF size: 80.80 Kb.

ABSTRACT

Background: Transbronchial needle aspiration biopsy is useful for the diagnosis of peripheral lesions, tumors producing extrinsic compression of the bronchus and for mediastinal lymph node sampling; forceps biopsy (FB) is useful for visible tumors and endobronchial lesions. The experience using endobronchial needle aspiration biopsy (EBNA) plus FB is limited.
Objectives: To identify the usefulness and diagnostic yield of EBNA alone and EBNA plus FB for the diagnosis of visible tumor and submucosal infiltration by tumor.
Methods: During fiberoptic bronchoscopy, we performed EBNA and FB, in that order, in patients with visible tumor or submucosal infiltration by tumor and determined the diagnostic yield for each, independently and associated.
Results: We include 32 patients. The final diagnosis by bronchoscopic methods was achieved in 28 (88%) patients and with other invasive methods in 4 (12%). In tumors, FB was diagnostic in 16 (84%) patients and EBNA in 3 (16%) (p 0.03), statistical ly significant (predictive positive value 90% and negative in 50%) in favor of FB. For tumoral infiltration, FB was diagnostic in 7 (54%) and EBNA in 6 (46%) (p 0.24), with similar yield for both techniques. FB alone was effective in 85% of patients, EBNA alone in 62% and both in combination up to 91%.
Conclusions: EBNA is a useful technique for the diagnosis of malignant neoplasms, alone and associated to FB. It is unexpensive, produces little trauma and avoids the risk of bleeding seen with other biopsy techniques.

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