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2007, Number 2

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Rev Mex Anest 2007; 30 (2)

Analgesic usefulness of tramadol hydrochloride for pain management

Trejo-Ángeles B, Guevara-López U, Ramos-Rocha P, Cruz-Orozco Ó, Covarrubias-Gómez A, Leal-Gudiño L, Gaspar-Carrillo SP

Language: Spanish
References: 30
Page: 91-96
PDF size: 73.07 Kb.


ABSTRACT

Objective: To evaluate the analgesic potency of tramadol hydrochloride (TH) for patients with moderate to severe pain, and its potential adverse effects. Method: Fifty-nine patients suffering pain of different type and intensity were given TH as analgesic monotherapy. The participants evaluated their baseline pain using an 11-points visual analogue scale (VAS) and answered a short version of the McGill questionnaire and to evaluate the analgesic effect of the drug, they answered twice VAS and registered its adverse effects. Data were analyzed by using descriptive statistics, t test, χ2 test and ANOVA; p values ‹ 0.05 were considered statistically significant. Results: Fifty-five patients were included in the analysis. The average mean of age was 55 years; 69.09% did not have cancer-related pain, while 30.9% did. 58% had chronic pain and 42% had acute pain; TH was given orally to 72.2% and 27.8% through intravenous injection. 36.3% of participants had secondary effects such as constipation (45%) dizziness (45%) nausea (20%) and diaphoresis (10%). Statistically significant differences were found between the baseline and post-intervention VAS evaluations (p ‹ 0.0001), while the type of pain, chronicity and drug route of administration did not show differences regarding pain intensity.


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