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ISSN 0185-3252 (Print)
Revista de la Asociación Médica del Centro Médico ABC

2003, Number 2

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An Med Asoc Med Hosp ABC 2003; 48 (2)

Latency time evaluation of intravenous rocuronium and lidocaine for orotracheal intubation. Comparison with succinilcoline

Acevedo RPE, Revilla PF, Vásquez MMT, Salazar MR

Language: Spanish
References: 18
Page: 97-101
PDF size: 56.34 Kb.


ABSTRACT

Our objective is to evaluate the effects of lidocaine and rocuronium bromide and the conditions of orotracheal intubation, during a rapid induction sequence, compared to succinilcoline. Seventy five patients, divided in five groups, ASA I-II, for major surgery, where neuromuscular relaxation was monitorized by train of four stimuli (TOF), it was also evaluated with a clinical intubation scale (FAHEY). We evaluated hemodynamic parameters and latency time of the study drugs. Statistical evaluation was performed by t Student test. The results showed statistical significance, on behalf of succinilcoline (p < 0.001), with the exception of group V (p > 0.05); however, we found a shorter latency time, for the groups IV and V where lidocaine was added (p < 0.001), compared with the succinilcoline group, they demonstrated as well better conditions of intubation and shorter latency time, compared with the groups where lidocaine was not used II and III (p < 0.001 and p < 0.05, respectively). 60% (9) of the patients of group V, where intubated with an average time of 36.8 seconds. Hemodynamic response to intubation did not present variation, compared with the basal values. The combination of lidocaine with rocuronium bromide, allows a shorter latency time and to obtain better intubating conditions, at the dosis used in out study.


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