Gutiérrez MCA, Reyes GE, Corona JF

Language: Spanish
References: 19
Page: 91-94
PDF size: 52.33 Kb.

ABSTRACT

The Stenotrophomona maltophilia Gram negative bacteria, that was considered like of limited pathogenicity, at the moment, is associated to an increase in morbi-mortality. Its presence represents a great problem due to its multiresistance.
Objective: To identify sensitivity to antibiotics of the Stenotrophomona maltophilia in the Unit of Intensive Therapy.
Patients and methods: It is a retrospective study of a series of cases, made in We have of the CMNO of the IMSS of Guadalajara, Jalisco. The files and report of cultures were reviewed during the period of the January of the 2003 until August of the 2006. Sensitivity was described the antimicrobial, reported in the final result of the culture.
Results: 66 positive cultures for Stenotrophomona maltophilia were identified, 55 of aspired bronchial, 5 hemocultures, 3 of abdominal secretion, 2 of venous catheters. Single 2 antibiotics showed good sensitivity, the Trimethoprim-Sulfamethoxazole (90%) and the Ofloxacina (84%).
Conclusion: The inhaled culture of bronchial (83%) was most frequent. It was demonstrated the multiresistance of this bacterium, to antimicrobial of frequent use.

REFERENCES

1. Drancourt et al. Stenotrophomonas africana. 1997 is a later synonym of Stenotrophomonas maltophilia. International Journal of Systematic and Evolutionary Microbiology 2004;54:1235-1237.

2. Apisarnthanarak A, Mayfield JL, Garison T et al. Risk factors for Stenotrophomonas maltophilia bacteremia in oncology patients: a case-control study. Infect Control Hosp Epidemiol 2003;24:269-274.

3. Senol E. Stenotrophomonas maltophilia: the significance and role as a nosocomial pathogen. Journal of Hospital Infection 2004; 57: 1-7.

4. Dina A, Yasmina A, De Donato M et al. Caracterización fenotípica y susceptibilidad antimicrobiana de cepas clínicas de Stenotrophomonas maltophilia. Kasmera 2005; 33(2):109-118.

5. Denton M, Kerr KG. Microbiological and clinical aspects of infection associated with Stenotrophomonas maltophilia. Clinical Microbiology Reviews 1998: 57-80.

6. Jennie L, Garison T, McLendon PM et al. Risk factors for Stenotrophomonas maltophilia bacteremia in oncology patients: a case-control study. Infect Control Hosp Epidemiol 2003;24:269-274.

7. Dalamaga M, Karmaniolas K, Chavelas Ch et al. Stenotrophomonas maltophilia: a serious and rare complication in patients suffering from burns. Burns 2003;29:711-713.

8. Wen-Ping, Chung-Lin, Wen-Chien, Shin-Chen P. Stenotrophomonas maltophilia bacteremia in burn patients. Burns :2006;32:155-158.

9. Calza L, Manfredi R, Chiodo F. Stenotrophomonas (Xanthomonas) maltophilia as an emerging opportunistic pathogen in association with HIV infection: a 10-year surveillance study. Infection 2003;31(3):155-61.

10. Manfredi R, Nanetti A, Ferri M, Chiodo F. Xanthomonas maltophilia: an emerging pathogen in patients with HIV disease. Int J STD AIDS 1998;9(4):201-7.

11. Del Toro M, Rodriguez J, Herrero M. Clinical epidemiology of Stenotrophomonas maltophilia; Colonization and Infection a Multicenter Study. MEDICINE® 2002;81:228-39.

12. Del Toro M, Rodriguez J, Herrero M. Fimbriae and adherence of Stenotrophomonas maltophilia to epithelial cells and to abiotic surfaces. Cellular Microbiology 2003;5(9):625-636.

13. Dentona M, Rajgopala A, Mooneyb L et al. Stenotrophomonas maltophilia contamination of nebulizers used to deliver aerosolized therapy to inpatients with cystic fibrosis. Journal of Hospital Infection 2003;55:180-183.

14. Rogues AM, Maugeiny J, Alleryy A et al. Electronic ventilator temperature sensors as a potential source of respiratory tract colonization with Stenotrophomonas maltophilia. Journal of Hospital Infection 2001;49:289-292.

15. Arvanitidou M, Vayona A, Spanakis N, Tsakris A. Occurrence and antimicrobial resistance of Gram-negative bacteria isolated in haemodialysis water and dialysate of renal units: results of a Greek multicentre study. J Appl Microbiol 2003;95(1):180-5.

16. Lin-Li Ch, Hui-Feng, Chung-Yu, Tsong-Ming. Contribution of integrons, and SmeABC and SmeDEF efflux pumps to multidrug resistance in clinical isolates of Stenotrophomonas maltophilia. Journal of Antimicrobial Chemotherapy 2004;53:518-521.

17. Clark RB. Imipenem resistance among Acinetobacter baumanni: association with reduced expression of 33-36 kda outer membrane protein. Journal of Antimicrobial Chemotherapy 1996;38:245-251.

18. Spencer J, Read J, Sessions RB. Antibiotic recognition by binuclear metallo-beta-lactamases revealed by X-ray crystallography. J Am Chem Soc 2005;127(41):14439-44.

19. Friedman D, Korman TM, Fairley CK et al. Bacteremia due to Stenotrophomonas maltophilia: An analysis of 45 episodes. N Journal of Infection 2002;45:47-53.