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2025, Number 1

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Arch Med Fam 2025; 27 (1)

Autism Spectrum Disorder in Preschoolers: Characteristics and Associated Risk Factors in a Family Medicine Unit in Mexicali, Baja California, Mexico

Cossío RDA, de León AM, Haro AME, Ayala FRI, Monge SLE

Language: Spanish
References: 24
Page: 23-26
PDF size: 163.91 Kb.


ABSTRACT

Objective: To determine the characteristics and risk factors associated with Autism Spectrum Disorder in children aged 3 to 6 years. Methods: Retrospective study in clinical records of children aged 3-6 years diagnosed with autism spectrum disorder in 2022 at the Family Medicine Unit No. 16 of Mexicali, Baja California of the Mexican Social Security Institute. The variables studied were: age, sex, family history of autism spectrum disorder and advanced age of parents, perinatal history and treatment. Results: 39 cases of patients aged 3 to 6 years were observed. The following predominated: Male sex 70.39%, average age 5.08 years, family history of autism 59%; history of prematurity 7.7% and fetal distress 17.9%. Pharmacological treatment 74.4% and stimulation 28.2%. Conclusions: The risk factors most frequently associated with autism were family history of this problem, fetal distress and prematurity. Most patients received pharmacological treatment and early stimulation therapy, almost a third of them.


REFERENCES

  1. Randall M, Sciberras E, Brignell A, Ihsen E, EfronD, Dissanayake C, et al. Autism spectrum disorder:Presentation and prevalence in a nationally representativeAustralian sample. Aust N Z J Psychiatry 2016;50(3):243-253. doi: 10.1177/0004867415595287.

  2. Organización Mundial de la Salud. Autismo. NotaDescriptiva 30 de marzo del 2022: Geneva WHO; 2022[acceso 19/11/2024]. Disponible en: https://www.who.int/es/news-room/fact-sheets/detail/autism-spectrum-disorders

  3. Statista Research Department. Prevalencia del autismoen niños en países seleccionados del mundo2022. 8 de abril 2022. [acceso 19/11/2024]. Disponibleen: https://es.statista.com/estadisticas/1225748/prevalencia-del-autismo-en-ninos-en-paises-seleccionados-del-mundo

  4. Celis Alcalá G, Ochoa Madrigal MG. Trastorno del EspectroAutista (TEA). Rev Fac Med UNAM 2022;65(1):7-20.http://doi.org/10.22201/fm.24484865e.2022.65.1.02

  5. Vázquez-Villagrán LL, Moo-Rivas CD, Meléndez-BautistaE, Magriñá-Lizama JS, Méndez-DomínguezNI. Revisión del trastorno del espectro autista: actualizacióndel diagnóstico y tratamiento. Rev MexNeuroci 2017 [acceso 20/11/2024];18(5):31-45. Disponibleen: https://previous.revmexneurociencia.com/wpcontent/uploads/2017/09/RevMexNeuroci_2017_18(5)-31-45-(R).pdf

  6. Reynoso C, Rangel MJ, Melgar V. El trastorno del espectroautista: aspectos etiológicos, diagnósticos y terapéuticos.Rev Med Inst Mex Seguro Soc 2017 [acceso21/11/2024];55(2):214-222. Disponible en: https://www.ncbi.nlm.nih.gov/pubmed/28296371

  7. Lara Correa DL, Utria Rodríguez O, Ávila-ToscanoJH. Factores de riesgo pre, peri y postnatales asociadosal género en niños y niñas con autismo. Int JPsychol Res 2012 [acceso 22/11/2024];5(2):77-90.Disponible en: https://www.redalyc.org/articulo.oa?id=299025051009

  8. American Academy of Pediatrics. 2016 Recommendationsfor Preventive Pediatric Health Care. Committeeon Practice and Ambulatory Medicine, Brigth FuturesPeriodicity Schedule Workgroup. Pediatrics 2016;137:e20153908. DOI: 10.1542/peds.2015-3908

  9. Cuesta JL, Sánchez S, Orozco ML, Valenti A, Cottini L.Trastorno del espectro del autismo: intervención educativay formación a lo largo de la vida. Psychol SocEdu. 2016;8(2):157-172. https://doi.org/10.25115/psye.v8i2.556

  10. Williamson E, Sathe NA, Andrews JC, KrishnaswamiS, McPheeters ML,Fonnesbeck C, et al. Medical Therapiesfor Children With Autism Spectrum Disorder—An Update. Rockville (MD): Agency for HealthcareResearch and Quality (US); 2017 [acceso 22/11/2024].Report No.: 17-EHC009-EF. PMID: 29064643.

  11. Sun X, Allison C, Wei L, Matthews FE, Auyeung B, WuYY, et al. Autism prevalence in China is comparable toWestern prevalence. Mol Autism 2019; 10(7):2-19. doi:10.1186/s13229-018-0246-0

  12. Yáñez C, Maira P, Elgueta C, Brito M, Crockett MA, TroncosoL, et al. Estimación de la prevalencia de trastornodel Espectro Autista en población urbana chilena.Andes Pediatr 2021;92(4):519–525. http://dx.doi.org/10.32641/andespediatr.v92i4.2503.

  13. Zeidan J, Fombonne E, Scorah J, Ibrahim A, Durkin MS,Saxena S, et al. Global prevalence of autism: A systematicreview update. Autism Res 2022;15(5):778-790.doi: 10.1002/aur.2696.

  14. Arberas C, Ruggieri V. Autismo. Aspectos genéticosy biológicos. Medicina (Buenos Aires) 2019 [acceso20/11/2024]; 79(Suppl1):16-21. Disponible en: https://www.scielo.org.ar/scielo.php?script=sci_arttext&pid=S0025-76802019000200005&lng=es.

  15. Bölte S, Girdler S, Marschik PB. The contribution of environmentalexposure to the etiology of autism spectrumdisorder. CMLS 2019; 76:1275–1297. https://doi.org/10.1007/s00018-018-2988-4

  16. Tick B, Bolton P, Happé F, Rutter M, Rijsdijk F. Heritabilityof autism spectrum disorders: a meta-analysis oftwin studies. J Child Psychol Psychiatry 2016; 7:585–595. doi: 10.1111/jcpp.12499.

  17. Merikangas AK, Calkins ME, Bilker WB, Moore TM, GurRC, Gur RE. Parental age and ofspring psychopathologyin the Philadelphia Neurodevelopmental Cohort. JAm Acad Child Adolesc Psychiatry 2017; 56:391–400.doi: 10.1016/j.jaac.2017.02.004.

  18. Janecka M, Mill J, Basson MA, Goriely A, Spiers H,Reichenberg A, et al. Advanced paternal age efectsin neurodevelopmental disorders-review of potentialunderlying mechanisms. Transl Psychiatry 2017;7(1):e1019. doi: 10.1038/tp.

  19. Thapar A, Rutter M. Genetic Advances in Autism. J AutismDev Disord 2021;51(12):4321-4332. doi: 10.1007/s10803-020-04685-z.

  20. Wang C, Geng H, Liu W, Zhang G. Prenatal, perinatal,and postnatal factors associated with autism: A meta-analysis. Medicine (Baltimore). 2017 May;96(18):e6696. doi: 10.1097/MD.0000000000006696.

  21. Hisle-Gorman E, Susi A, Stokes T, Gorman G, Erdie-LalenaC, Cade MN. Prenatal, perinatal, and neonatal riskfactors of autism spectrum disorder. Pediatr Res 2018;84:190–198. https://doi.org/10.1038/pr.2018.23

  22. Sousamli A, Dragioti E, Metallinou D, Lykeridou A,Dourou P, Athanasiadou CR, et al. Perinatal and demographicrisk factors associated with Autism

  23. Spectrum Disorder: A National Survey of PotentialPredictors and Severity. Healthcare 2024;12(20):2057.https://doi.org/10.3390/healthcare12202057

  24. Grañana N. Espectro Autista; una propuesta de intervencióna la medida, basada en evidencia. Rev MedClin Condes 2022; 33(4) 414-423.




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