2024, Number 2
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Rev Med UAS 2024; 14 (2)
Recurrence of dysmenorrhea in patients with peritoneal endometriosis treated with laparoscopic peritonectomy
López-Zepeda MA, Robles-López FM, López-de la Torre MA, MorganOrtiz F
Language: Spanish
References: 26
Page: 113-121
PDF size: 413.86 Kb.
ABSTRACT
Objective: Determine the effect of peritonectomy on pelvic pain in patients with endometriosis.
Patients and method: Prospective, longitudinal and observational study in patients with peritoneal endometriosis and pelvic pain undergoing
peritonectomy at the Endometriosis Clinic of Excellence in Guadalajara, Jalisco. Pain intensity was evaluated using the visual analogue scale
(VAS) before and 12 months after the procedure. The stage of the disease was also classified with ASRM and AAGL, and secondary variables
such as pregnancies, evolution of dysmenorrhea, previous surgeries, medical management, duration of the procedure, blood loss and complications were analyzed.
Results: 213 procedures were performed, with a mean age of 32.9 years (range 15-54). Of the patients, 106 (49.8%) were married and 107
(50.2%) were single. Nuligpes were 147 (69.01%) and 46.4% of the patients were free of dysmenorrhea between 2 and 4 years after surgery.
The disease stages were: rASM (I: 4.69%, II: 22.5%, III: 30.04%, IV: 42.7%) and AAGL (I: 4.69%, II: 14.55%, III: 16.43%, IV: 64.31%). Blood
loss ranged from 10 to 700 ml, and the average surgical time was 177.5 minutes. The mean pain before and after surgery was 9.0 and 1.0,
respectively, with an average reduction of 7.9 points on the VAS (p‹0.001).
Conclusions: Laparoscopic peritonectomy is effective in the management of peritoneal endometriosis, with a 46.4% absence of dysmenorrhea at 2 years and an average decrease of 7.9 points in pain intensity.
REFERENCES
Chamié L, Blasbalg R, Pereira R. Findings of pelvic endometriosis at transvaginal US, MR imaging, and laparoscopy. Radio Graphics 2011;31(4): E77-E100.
Johnson N, Hummelshoj L, Adamson G. WorldEndometriosis Society consensus on the classification of endometriosis. Hum Rep 2016; 32(2): 315-324.
Ayala YR, González MM. Endometriosis: fisiopatología y líneas de investigación. Ginecol ObstetMex 2007;75(8):477-83.
Krina T, Phil D, Christian M, Stacey A. Endometriosis. NEJM 2020; 382:1244-56.
Grümmer R, Schwarzer F, Bainczyk K. Peritoneal endometriosis: validation of an in-vivo model. Hum Rep 2001; 16(8): 1736-1743.
Marco L, Fred M, Manuel L. Endometriosis peritoneal, ovárica e infiltrativa: una revisión. RevMed UAS 2015; 5(2):72-88.
Charles M, Errico Z, Andrea T. Endometriosis:advances and controversies in classification,pathogenesis, diagnosis and treatment. F1000Faculty Rev 2019;529.
Richard O, Linda C. Pathogenesis and Phatophysiology of endometriosis. Fertil Steril 2012. 98(3)511-9.
Sachedina A, Todd N. Dysmenorrhea, Endometriosis and Chronic Pelvic Pain in Adolescents. JClin Res Pediatr Endocrinol. 2020 Feb6;12(Suppl 1):7-17.
Gruber TM, Mechsner S. Pathogenes of Endometriosos: The origin of pain and subfertility. Cells 2021;10(6)1381.
Morotti M, Vincent K, Becker CM. Mechanismsof pain in endometriosis. Eur J Obstet GynecolReprod Biol. 2017 Feb;209:8-13
Kho RM, Andres MP, Borrelli GM, Neto JS, Zanluchi A, Abrăo MS. Surgical treatment of differenttypes of endometriosis: Comparison of major society guidelines and preferred clinical algorithms.Best Pract Res Clin Obstet Gynaecol. 2018Aug;51:102-110.
Canis M, Bourdel N, Botschorishvili R, Rabischong B et al. Endometrioma ovárico. EMCGinecología-Obstetricia 2015;52:1-15.
Vimercati A, Achilarre M, Scardapane A. Accuracy of transvaginal sonography and contrast‐enhanced magnetic resonance‐colonography forthe presurgical staging of deep infiltrating endometriosis. ISOUG 2012; 40(5): 592-603.
Gambone J, Mittman B, Munro M. Chronic PelvicPain/Endometriosis Working Group. Consensusstatement for the management of chronic pelvicpain and endometriosis: proceedings of an expert-panel consensus process. Fertnstert 2002;78(5): 961-972.
Mehedintu C, Plotogea MN, Ionescu S. Endometriosis still a challenge. J Med Life. 2014 Sep15;7(3):349-57.
Vercellini P, Crosignani P, Abbiati A. The effectof surgery for symptomatic endometriosis: the other side of the story. Hum Reprod 2009; 15(2):177-188.
Holland T, Yazbek J, Cutner A. Value of transvaginal ultrasound in assessing severity of pelvicendometriosis. Ultrasound Obstet Gynecol2010; 36(2): 241-248.
Guo S. Recurrence of endometriosis and its control. Hum Reprod 2009; 15(4): 441-461.
Becker CM, Bokor A, Heikinheimo O. ESHREEndometriosis Guideline Group. ESHRE guideline: endometriosis. Hum Reprod Open. 2022Feb 26;2022(2):hoac009
Goncalves M, Podgaec S, Dias Jr A. Transvaginal ultrasonography with bowel preparation isable to predict the number of lesions and rectosigmoid layers affected in cases of deep endometriosis, defining surgical strategy. Hum Reprod 2009; 25(3): 665-671.
Ceccaroni M, Bounous VE, Clarizia R. Recurrentendometriosis: a battle against an unknownenemy. Eur J Contracept Reprod Health Care.2019 Dec;24(6):464-474.
Carvajal A, Braghetto I, Carvajal R, Miranda C.Endometriosis de la pared abdominal. Rev ChilObstet Ginecol 2007; 72(2): 105-110.
Sugarbaker PH. Peritonectomy procedures.Cancer Treat Res. 2007;134:247-64.
Abesadze E, Sehouli J, Mechsner S, ChianteraV. Possible Role of the Posterior CompartmentPeritonectomy, as a Part of the Complex Surgery, Regarding Recurrence Rate, Improvementof Symptoms and Fertility Rate in Patients withEndometriosis, Long-Term Follow-Up. J MInimInvasive Gynecol 2020; 27(5):1103-1111.
de Arellano ML, Mechsner, S. The peritoneum—an important factor for pathogenesis and paingeneration in endometriosis. J Mol Med 2014;92: 595–602.