2022, Number 2
PredRCG_aps study: Prediction of global cardiovascular risk in primary health care
Language: Spanish
References: 26
Page: 26
PDF size: 362.30 Kb.
ABSTRACT
Introduction: Cardiovascular diseases are a major cause of disability and mortality worldwide. In Cuba there is not a scoring method to calculate cardiovascular risk based on large cohort of the population.Objective: To design a predictive model to provide accurate prediction of the global cardiovascular risk in primary health care.
Methods: A PredRCG_aps study, based in a large prospective cohort, between 35 to 74 years old, followed during 10.6 ± 1.24 years, from 2008 to 2019, in the Teaching Polyclinic of Velasco, Holguín, Cuba. A predictive model based on Cox proportional hazard model was designed; a report is presented on selection and the baseline characteristics of the population, the definitions of the parameters and the study methodology.
Results: The cohort included 1633 individuals, mean age was 52 years old, 52.5% female; in 351 patients of both sexes(21.5%), the level of high sensitivity c reactive protein was equal or more than 3 mg/dl, which is a marker of inflammation and endothelial damage, predictors such as triglycerides, abdominal circumference, fasting plasma glycemia and high-sensitivity c-reactive protein were incorporated; good model performance was obtained, area under the ROC curve of 0.966 and 0.973 in both males and females.
Conclusions: A predictive model (PredRCG_aps) was design with the exposed methodology, which will be a useful tool to prevent cardiovascular diseases in primary health care.
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