2024, Number 3
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Med Crit 2024; 38 (3)
Correlation of ionized calcium levels and base excess with bleeding volume in major obstetric hemorrhage in the ICU
Medina LJL, Ríos PMA
Language: Spanish
References: 18
Page: 169-175
PDF size: 274.79 Kb.
ABSTRACT
Introduction: obstetric hemorrhage continues to be the leading cause of maternal morbidity and mortality worldwide, being higher in developing countries. It occurs in 5% of all births and causes 140,000 deaths per year, equivalent to one death every 4 minutes. Most deaths occur within the first 4 hours postpartum. Obstetric hemorrhage is a health problem and has a high incidence of morbidity and mortality in low- and middle-income countries. It is important to identify factors that can contribute to reducing the risk of obstetric bleeding. As we will see in this work, calcium is a cofactor of coagulation that is related to the production of a quality coagulum as well as an ion that has been implicated in the improvement of uterine tone. In the present work we intend to determine whether the levels of ionized calcium as well as the levels of base excess are closely related to the total volume of bleeding after a delivery or cesarean section with major obstetric hemorrhage.
Objective: calcium is a coagulation cofactor that is related to the production of a quality clot as well as an ion that has been implicated in the improvement in uterine tone. The main objective of this study is to determine if there is a linear variation between the levels of ionized calcium and base excess with blood volume in obstetric hemorrhage.
Material and methods: an observational, correlational, single-center, retrospective study was developed, 54 patients admitted to the obstetric ICU with a diagnosis of major obstetric hemorrhage were included, where a Pearson correlation analysis was performed for the variables of ionized calcium levels, excess base, and blood volume.
Results: statistical significance was found between ionized calcium, base excess and blood volume, obtaining that the compensation with the greatest power was ionized calcium -0.34, for base excess we obtained a weak compensation of -0.29.
Conclusion: there is inverse variation between levels of ionized calcium, base excess with the volume of bleeding in obstetric hemorrhage.
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