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Boletín Médico del Hospital Infantil de México

2006, Number 5

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Bol Med Hosp Infant Mex 2006; 63 (5)

Henoch-SChönlein purpura in children: Report of 105 patients

Cáceres-Mosquera J, Fuentes-Velasco Y, Romero-Navarro B, Valverde-Rosas S, García-Roca P, Gomezchico-Velasco R, Ramón-García G, Carreño-Manjarrez R, Maldonado R, Velásquez-Jones L, Medeiros-Domingo M

Language: Spanish
References: 25
Page: 314-321
PDF size: 71.42 Kb.


ABSTRACT

Introduction. Henoch-Schönlein purpura (HSP) is the most frequent vasculitis in children. Objective: To describe the clinical presentation and clinical outcome in children with HSP treated in our hospital in the last 5 years.
Material and methods. A retrospective study was performed in HSP patients diagnosed between January 1st 2001 and December 31st 2005.
Results. HSP was diagnosed in 105 patients, median age 6 years old. All had the skin manifestations, 49.5% abdominal pain and 41% arthritis; 45 patients developed HSP nephritis (42.9%), mean presentation time was 4.5 months after HSP diagnosis. Renal biopsy was performed in 14 patients, and the most common histopathological finding was HSP nephritis grade III A. Age of onset older than 10 years was statistically significant for nephritis development (Chi Square ‹0.05). Chronic renal insufficiency incidence was 0.95%.
Conclusions. The main complication of HSP is nephritis. Follow-up should include evaluation by a pediatric nephrologist. Age of onset older than 10 years is an important risk factor for HSP nephritis.


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