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Archivos de Medicina de Urgencia de México

2024, Number 1

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Arch Med Urg Mex 2024; 16 (1)

Pharmacological neurorehabilitation in cerebral infarction: the potential of cerebrolysin

Cantú-Brito C, Arellano-Ramírez A, Hernández-Cruz MJ, Galván-Merlos MA

Language: Spanish
References: 35
Page: 12-21
PDF size: 790.52 Kb.


ABSTRACT

Neurological rehabilitation has made notable progress in restoring stroke-related motor function. About 40% of patients who develop upper limb motor disease remain disabled for all life despite receiving intensive physical therapy. For this reason, the need to have pharmacological interventions that influence the neurorehabilitation of people with motor dysfunction has been emphasized. The present review analyzes the potential of Cerebrolysin in functional recovery in patients with stroke, supported by experimental evidence from basic sciences and neuroimaging studies that evaluate neuroplasticity, as well as its inclusion in the Motor Rehabilitation Guidelines in Patients with Acute Cerebral Infarction.
Finally, the combination of physical rehabilitation with neuro-reparative drugs is a novel therapeutic approach. Cerebrolysin provides favorable effects in the restoration of motor function, preserves the integrity of the network motor during the process of neuronal reorganization after cerebral infarction.


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