2024, Number 1
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Rev Nefrol Dial Traspl 2024; 44 (1)
Rehospitalization after kidney transplantation
Claros IA, Magenta M, Rodríguez CLM, Fragale G, Tisi BM
Language: Spanish
References: 12
Page: 18-23
PDF size: 256.25 Kb.
ABSTRACT
Introduction: Rehospitalization
after renal transplantation predicts
morbidity and mortality, is associated
with higher costs, and indicates health
care quality. Identifying risk factors
for rehospitalization makes it possible
to implement measures that improve
the quality of care and develop
interventions in the pre-transplant
stage. Objectives: Establish the
incidence of early rehospitalization
in renal transplantation and
evaluate variables associated with
rehospitalization and its impact on
the recipient and graft.
Materials
and Methods: Observational,
longitudinal, retrospective study. We
analyzed a cohort of adult kidney
transplant patients from 01/01/2006 to
12/31/2018.
Results: 196 adult kidney
transplant patients were included
in the study. The incidence of early
rehospitalization was 17.8% (n=35).
Patient and graft survival were similar
in both groups. The cause of death was
predominantly infectious 52% (n=22),
while the cause of graft loss was chronic
allograft nephropathy 24% (n=14) and
death with a functioning graft 48%
(n=28).
Conclusions: The incidence
of early rehospitalization after renal
transplantation in our center is low
compared to other publications. Our
study did not show that readmission
after renal transplantation is associated
with worse outcomes.
REFERENCES
Wolfe RA, Ashby VB, Milford EL, Ojo AO, EttengerRE, Agodoa LYC, Held PJ, Port FK: Comparisonof mortality in all patients on dialysis, patients ondialysis awaiting transplantation, and recipients of afirst cadaveric transplant. N Engl J Med 341:1725–1730, 1999.
McAdams-Demarco MA, Grams ME, Hall EC, et al.Early hospital readmission after kidney transplantation:patient and center-level associations. Am J Transplant.2012; 12:3283–3288.
McAdams-Demarco MA, Grams ME, King E, DesaiNM, Segev DL. Sequelae of early hospital readmissionafter kidney transplantation. Am J Transplant.2014;14(2):397‐403.
Harhay M, Lin E, Pai A, et al. Early rehospitalizationafter kidney transplantation: assessing preventabilityand prognosis. Am J Transplant. 2013;13(12):3164‐3172.
Lubetzky M, Yaffe H, Chen C, Ali H, Kayler LK.Early readmission after kidney transplantation:examination of discharge‐level factors. Transplantation.2016;100(5):1079‐1085.
Kinza Iqbal, Muhammad Hasanain, Sawai SinghRathore, Ayman Iqbal et al. Incidence, predictors, andoutcomes of early hospital readmissions after kidneytransplantation: Systemic review and meta-analysis.Front Med. 2022 Nov 4;9:1038315. doi: 10.3389/fmed.2022.1038315
Mohammadi K, Khajeh B, Dashti-Khavidaki S,Shab-Bidar S. Association between cumulativerATG induction doses and kidney graft outcomesand adverse effects in kidney transplant patients:a systematic review and meta-analysis. ExpertOpin Biol Ther. 2021 Sep;21(9):1265-1279. doi:10.1080/14712598.2021.1960978. Epub 2021 Aug 4.PMID: 34304664.
Taber DJ, Pilch NA, McGillicuddy JW, Bratton CF,Lin A, Chavin KD, et al. Improving the perioperativevalue of care for vulnerable kidney transplant recipients.J Am Coll Surg. (2013) 216:668–78. doi: 10.1016/j.jamcollsurg.2012.12.023
Leppin AL, Gionfriddo MR, Kessler M, Brito JP, MairFS, Gallacher K, et al. Preventing 30-day hospitalreadmissions: a systematic review and meta-analysis ofrandomized trials. JAMA Intern Med. (2014) 174:1095–107. doi: 10.1001/jamainternmed.2014.1608
Fragale G, Mainetti L, Montal S, Beitia V, LovisoloP, Karl A et al. Plan estratégico para la reducción de laestancia hospitalaria en trasplante renal. J Healthc QualRes. 2018;33(6):329-333
Tapiawala SN, Tinckam KJ, Cardella CJ, Schiff J,Cattran DC, Cole EH, Kim SJ. Delayed graft functionand the risk for death with a functioning graft. J AmSoc Nephrol. 2010 Jan;21(1):153-61. doi: 10.1681/ASN.2009040412. Epub 2009 Oct 29. PMID:19875806; PMCID: PMC2799285
Yarlagadda SG, Coca SG, Formica RN, Poggio ED,Parikh CR. Association between delayed graft functionand allograft and patient survival: a systematicreview and meta-analysis. Nephrol Dial Transplant.2009;24(3):1039-1047.