Alfaro-Flores P, Becerra-Aguiar NN, Bonilla-Dávalos FE, Campa-Santos DI, Hurtado-Cuan P, Méndez-García CA, Plascencia-De LCM, Rodríguez-Aceves A, Salas-Bonales V, Santoscoy-García R

Language: Spanish
References: 15
Page: 16-21
PDF size: 226.60 Kb.

ABSTRACT

Inflammation is defined as a natural physiological process of the body that responds to tissue damage, infections, or pathological processes. The main objective of this review is to gather existing evidence in the scientific literature of the last 10 years on the relationship between the presence of molecular biomarkers of inflammation and the development and progression of prevalent mental disorders such as schizophrenia, post-traumatic stress disorder (PTSD), bipolar disorder (BD), and major depressive disorder (MDD). In conclusion, the presence of markers such as interleukins (IL) 1, 2, 6, 7, 8, and 12, tumor necrosis factor alpha (TNF-α), and vascular endothelial growth factor (VEGF) have been identified in patients living with PTSD, BD, or MDD. However, the presence or absence of these markers is not pathognomonic for the development of any of these diseases, so further research is needed to better understand the relationship between inflammation and mental disorders.

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