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Colegio de Medicina Interna de México.

2024, Number 1

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Med Int Mex 2024; 40 (1)

Acute liver failure secondary to the use of intravenous amiodarone

Núñez MFJ, Chávez LAJ, Orozco JK, Velasco SJI

Language: Spanish
References: 19
Page: 59-63
PDF size: 225.44 Kb.


ABSTRACT

Background: Amiodarone is a commonly used drug with a long half-life that is associated with asymptomatic hepatotoxicity; however, acute toxicity is rare, with few reported cases of acute liver failure secondary to amiodarone, and in all these cases the outcome was fatal during hospitalization.
Clinical cases: A 63-year-old male patient with uncontrolled atrial fibrillation who developed fulminant hepatic failure within 24 hours after administration of IV amiodarone at the recommended dose.
Conclusions: It is important that we as doctors are aware of this complication that, although rare, is potentially fatal, so that in the event of any signs of liver failure we withdraw the drug.


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