2023, Number 5
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Acta Pediatr Mex 2023; 44 (5)
Neurological manifestations temporarily associated with COVID-19 infection in pediatric patients in Mexico
Ruiz GM, Hernández ABG, Herrera MP, Camacho ME, Urrutia OM, Sánchez MAE, Rosales PG, Dávila ML
Language: Spanish
References: 22
Page: 345-352
PDF size: 212.13 Kb.
ABSTRACT
Background: During the coronavirus pandemic, various neurological manifestations
have been reported. The pediatric population is affected less frequently and seriously.
Objective: To evaluate the association between acute neurological symptoms in
pediatric patients with confirmed COVID - 19 infection.
Design: Case series of patients with acute neurological symptoms temporarily associated
with SARS-CoV-2 infection; Patients younger than 17 years of age with
Guillainacute
symptoms such as ascending weakness with areflexia, decreased visual acuity,
encephalopathy, ischemic cerebrovascular event, or muscle weakness with elevations
of plasma creatinine kinase (CK) were evaluated.
Results: In this study, 23 patients with neurological symptoms who attended the
emergency room consecutively over a period of 4 months were evaluated. 10 had a
history of contact or infection with SARS-CoV-2. There were 5 men from 2 to 16 years
old (mean age 11.6), 4 of them had contact with a relative who presented SARS-CoV-2,
and 2 had respiratory symptoms related to the disease of SARS-CoV-2 in the two weeks
prior to the onset of neurological symptoms related to the following pathologies: Optic
neuritis ((n = 2), Guillain-Barré syndrome (n = 3), myositis with rhabdomyolysis (n
= 1), ischemic vascular event (n = 2) , acute cerebellitis (n = 1), and Anti NMDA-R
encephalitis (n = 1).
Conclusions: Neurological manifestations temporarily associated with COVID-
19 infections are present in the pediatric population even in the absence of
respiratory symptoms. COVID-19 infection should be considered as an etiology
in patients with neurological symptoms, especially if there is a history of contact
with a confirmed case.
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