2023, Number 6
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Med Int Mex 2023; 39 (6)
Severity of symptoms in patients with chronic end-stage kidney disease treated with hemodialysis in a second-level care hospital
Chong FME, Vilchis CE, Moranchel GL
Language: Spanish
References: 34
Page: 873-882
PDF size: 212.64 Kb.
ABSTRACT
Objective: To evaluate the frequency and severity of symptoms in relation to effective
hemodialysis in patients with end-stage renal disease.
Materials and Methods: Cross-sectional, analytical study performed in patients
with end-stage renal disease in the hemodialysis unit of a secondary care hospital in
Mexico City. Variables were: sex, age, comorbidities, vascular access, voiding volume,
number of sessions per week, time on hemodialysis, dry weight, ultrafiltered volume,
duration of treatment, Kt/V and symptoms presented. The instrument used was Modified
Edmonton Symptom Assessment System.
Results: There were included 75 patients, from which 68% were men, mean age:
60.64 ± 13.41 years; comorbidities: 6.7% had type 2 diabetes, 24% systemic arterial
hypertension and 69.3% both. Regarding vascular access: 52% had a fistula, 22.7% a
temporary catheter and 25.3% a tunneled catheter; 52% presented urination greater
than 100 mL in 24 hours; sessions per week: 3; mean time on hemodialysis: 4 years;
dry weight: 69.99 kg; 2096.53 mL of ultrafiltered volume. Average session/treatment
duration: 3.0967 ± 0.26 hours. The correlation of the Kt/V level and severity of the
significant symptoms were xerostomia and edema (Student’s t p ‹ 0.05).
Conclusions: The serious symptoms in patients undergoing hemodialysis have been
scarcely studied, so it is important to manage prevention and treatment measures for
this group in a vulnerable situation.
REFERENCES
Kidney Disease: Improving Global Outcomes (KDIGO)Diabetes Work Group. KDIGO 2022 Clinical PracticeGuideline for Diabetes Management in Chronic KidneyDisease. Kidney Int 2022; 102 (5S): S1-S127. doi: 10.1016/j.kint.2022.06.008.
Bolignano D, Mattace-Raso F, Sijbrands EJG, Zoccali C. Theaging kidney revisited: A systematic review. Ageing Res Rev2014; 14: 65-80. doi: 10.1016/j.arr.2014.02.003.
Rovin, B. H. Do kidneys grow old gracefully? Kidney Int2020; 97 (1): 40-41. doi: 10.1016/j.kint.2019.08.031.
Weckmann GF, Stracke S, Haase A, Spallek J, Ludwig F,Angelow A, Chenot JF. Diagnosis and management ofnon-dialysis chronic kidney disease in ambulatory care: asystematic review of clinical practice guidelines. BMC Nephrol2018; 19 (1): 1-18. doi: 10.1186/s12882-018-1048-5.
Grill AK, Brimble S. Approach to the detection and managementof chronic kidney disease: What primary careproviders need to know. Can Fam Physician 2018; 64 (10):728-35.
Stanifer JW, Von Isenburg M, Chertow GM, Anand S. Chronickidney disease care models in low- and middle-incomecountries: a systematic review. BMJ Glob Health 2018; 3(2): e000728. doi:10.1136/bmjgh-2018-000728.
Webster AC, Nagler E V, Morton RL, Masson P. ChronicKidney Disease. Lancet 2017; 389 (10075): 1238-52. doi:10.1016/S0140-6736(16)32064-5.
Romagnani P, Remuzzi G, Glassock R, Levin A, Jager KJ,Tonelli M, et al. Chronic kidney disease. Nat Rev Dis Prim2017; 3 (1): 17-28. https://doi.org/10.1038/nrdp.2017.88.
Thurlow JS, Joshi M, Yan G, Norris KC, Agodoa LY, YuanCM, Nee R. Global epidemiology of end-stage kidney diseaseand disparities in kidney replacement therapy. AmJ Nephrol 2021; 52 (2): 98-107. doi: 10.1159/000514550.
Gotch FA, Sargent JA. A mechanistic analysis of the NationalCooperative Dialysis Study (NCDS). Kidney Int 1985; 28 (3):526-34. doi: 10.1038/ki.1985.160.
Maruyama Y, Yokoyama K, Higuchi C, Sanaka T, TanakaY, Sakai K. EARTH (Evaluation of the Adequacy of Renalreplacement Therapy) study group. Clinical feasibility oftransfer to combined therapy with peritoneal dialysisand hemodialysis for patients on peritoneal dialysis: Aprospective multicenter study in Japan. Therc Apher Dial2022; 26 (6): 1226-1234. doi: 10.1111/1744-9987.13796.
Ashby D, Borman N, Burton J, Corbett R, Davenport A,Farrington K, Wilkie M. Renal association clinical practiceguideline on haemodialysis. BMC Nephrol 2019; 20 (1):1-36. https://doi.org/10.1186/s12882-019-1527-3.
Vanholder R, Glorieux G, Eloot S. Once upon a time indialysis: the last days of Kt/V? Kidney Int 2015; 88 (3):460-465. doi: 10.1038/ki.2015.155.
Van der Tol A, Lameire N, Morton RL, Van Biesen W,Vanholder R. An international analysis of dialysis servicesreimbursement. Clin J Am Soc Nephrol 2019; 14 (1): 84-93.doi: 10.2215/CJN.08150718.
Yan G, Shen JI, Harford R, Yu W, Nee R, Clark MJ, Norris KC.Racial and ethnic variations in mortality rates for patientsundergoing maintenance dialysis treated in US territoriescompared with the US 50 states. Clin J Am Soc Nephrol2020; 15 (1): 101-108. doi: 10.2215/CJN.03920319.
Rezaiee O, Shahgholian N, Shahidi S. Assessment of hemodialysisadequacy and its relationship with individual andpersonal factors. Iran J Nurs Midwifery Res 2016; 21 (6):577-82. doi: 10.4103/1735-9066.197673.
Davison SN, Jhangri GS, Johnson JA. Longitudinal validationof a modified Edmonton symptom assessment system(ESAS) in haemodialysis patients. Nephrol Dial Transplant2006; 21 (11): 3189-95. doi: 10.1093/ndt/gfl380.
Kuipers J, Verboom LM, Ipema KJ, Paans W, Krijnen WP,Gaillard CA, Franssen CF. The prevalence of intradialytichypotension in patients on conventional hemodialysis: asystematic review with meta-analysis. Am J Nephrol 2019;49 (6): 497-506. doi: 10.1159/000500877.
Sánchez Cabezas AM, Morillo Gallego N, Merino Martínez RM,Crespo Montero R. Calidad de vida de los pacientes en diálisis.Revisión sistemática. Enferm Nefrol 2019; 22 (3): 239-55.
Hui D, Bruera E. The Edmonton Symptom AssessmentSystem 25 years later: past, present, and future developments.J Pain Symptom Manage 2017; 53 (3): 630-43. doi:10.1016/j.jpainsymman.2016.10.370.
Bruera E, Kuehn N, Miller MJ, Selmser P, Macmillan K. TheEdmonton Symptom Assessment System (ESAS): a simplemethod for the assessment of palliative care patients. JPalliat Care 1991; 7 (2): 6-9.
Davison SN, Jhangri GS, Johnson J A. Cross-sectional validityof a modified Edmonton symptom assessment system indialysis patients: a simple assessment of symptom burden.Kidney Int 2006; 69 (9): 1621-1625. doi: 10.1038/sj.ki.5000184.
Pérez-García R, Jaldo M, Alcázar R, de Sequera P, AlbalateM, Puerta M, Corchete E. El Kt/V alto, a diferencia del Kt, seasocia a mayor mortalidad: importancia de la V baja. Nefrología2019; 39 (1): 58-66. DOI: 10.1016/j.nefro.2018.04.006.
Evans JM, Glazer A, Lum R, Heale E, MacKinnon M, Blake PG,Walsh M. Implementing a patient-reported outcome measurefor hemodialysis patients in routine clinical care: Perspectivesof patients and providers on ESAS-r:renal. Clin J Am Soc Nephrol2020; 15 (9): 1299-1309. doi: 10.2215/CJN.01840220.
Frantz J, Rhoda A. Overview of self-management. selfmanagementin chronic illness: principles, practice, and empowermentstrategies for better health. Springer 2021; 3-9.
Ng MSN, Miaskowski C, Cooper B, Hui YH, Ho EHS, Mo SKL,So WKW. Distinct symptom experience among subgroupsof patients with ESRD receiving maintenance dialysis. JPain Symptom Manage 2020; 60 (1): 70-79. doi: 10.1016/j.jpainsymman.2020.01.004.
Chuasuwan A, Pooripussarakul S, Thakkinstian A, IngsathitA, Pattanaprateep O. Comparisons of quality of lifebetween patients underwent peritoneal dialysis andhemodialysis: a systematic review and meta-analysis.Health Qual Life Outcomes 2020; 18: 1-11. doi: 10.1186/s12955-020-01449-2.
Davison SN, Rathwell S, Ghosh S, George C, Pfister T,Dennett L. The prevalence and severity of chronic painin patients with chronic kidney disease: A systematicreview and meta-analysis. Can J Kidney Health Dis 2021;8: 2054358121993995. doi: 10.1177/2054358121993995.
Zhang, K, Hannan, E, Scholes-Robertson, N, Baumgart,A, Guha, C, Kerklaan, J, Tong, A. Patients’ perspectives ofpain in dialysis: systematic review and thematic synthesisof qualitative studies. Pain 2020; 161 (9): 1983-1994. doi:10.1097/j.pain.0000000000001931.
Lambourg E, Colvin L, Guthrie G, Murugan K, Lim M, WalkerH, Bell S. The prevalence of pain among patients withchronic kidney disease using systematic review and metaanalysis.Kidney Int 2021; 100 (3): 636-649. doi: 10.1016/j.kint.2021.03.041.
Cox KJ, Parshall MB, Hernandez SHA, Parvez SZ, Unruh ML.Symptoms among patients receiving in-center hemodialysis:A qualitative study. Hemodial Int 2017; 21 (4) :524-33.doi: 10.1111/hdi.12521.
Flythe JE, Hilliard T, Castillo G, Ikeler K, Orazi J, Abdel-Rahman E, Mehrotra R. Symptom prioritization amongadults receiving in-center hemodialysis: a mixed methodsstudy. Clin J Am Soc Nephrol 2018; 13 (5): 735-745. doi:10.2215/CJN.10850917.
Raj R, Ahuja KD, Frandsen M, Jose M. Symptoms and theirrecognition in adult haemodialysis patients: interactionswith quality of life. Nephrology 2017; 22 (3): 228-233. doi:10.1111/nep.12754.
Zuvela J, Trimingham C, Le Leu R, Faull R, Clayton P, JesudasonS, Meade A. Gastrointestinal symptoms in patientsreceiving dialysis: a systematic review. Nephrology 2018;23 (8): 718-727. doi: 10.1111/nep.13243.