Mercado U, Torres K, Renee SD

Language: Spanish
References: 10
Page: 815-820
PDF size: 206.14 Kb.

ABSTRACT

Background: Systemic lupus erythematosus is a systemic inflammatory disease characterized by multiple autoantibodies, some of the pathogenic as anti-Ro/La (neonatal blockade), antiphospholipid (thrombosis) and anti-ADN (nephritis).
Clínical Cases : This study includes a series of cases from our systemic lupus erythematosus cohort that presented to the emergency room without a previously established diagnosis. Seven cases were identified as the initial manifestation of the disease, 5 women and 2 men with a median age of 17 years. For the diagnosis, the new 2019 ACR/EULAR classification criteria were used, which include seven clinical manifestations (skin, arthritis, fever, neurological, serositis, hematological and kidney) and three immunological criteria. Systemic lupus erythematosus is classified with a score of 10 or more. The manifestations were serositis, arterial thrombosis with associated antiphospholipid antibodies, psychosis, transverse myelitis, and probable cerebral vasculitis. All patients received immunosuppressants with high doses of steroids with subsequent reduction.
Conclusions: Several forms of initial manifestation of systemic lupus erythematosus have been described. A high index of suspicion for autoimmune disease is necessary in young subjects, particularly systemic lupus erythematosus.

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