2021, Number 4
Prognostic assessment of death due to cardiorenal syndrome in patients with acute myocardial infarction
Language: Spanish
References: 34
Page:
PDF size: 721.74 Kb.
ABSTRACT
Introduction: Cardiorenal syndrome represents the worsening of the renal function in patients with acute myocardial infarction and is considered an independent risk factor of increased mortality.Objective: To identify the prognostic factors of death in infarcted patients with cardiorenal syndrome.
Methods: An analytical study of cases and witnesses was made with 123 patients diagnosed with cardiorenal syndrome due to acute myocardial infarction, admitted in the Coronary Intensive Care Unit of Carlos Manuel de Céspedes General Teaching Hospital, Granma, Cuba, from January 12, 2017 to July 12, 2020. Odds Ratio (OR) and its 95% confidence intervals (95%CI) of the factors in simple and multiple logistic regression were calculated in SPSS 24 for Windows.
Results: The prevalence of cardiorenal syndrome was 37.2% with mean age 62.4 (12.8) years. Sample mortality due to cardiorenal syndrome was 33.3% (41 patients out of 123). Predictor independent variables of death due to cardiorenal syndrome were metabolic syndrome (OR = 3.8; 95%IC = 1.2- 12), left ventricular dysfunction (OR = 2.6; 95%IC = 1.2- 5.1) and glomerular filtration rate < 74 ml/min/1.73 m2 (OR = 2; 95%IC = 1.1-9.6).
Conclusions: Death risk increased from 2 to 3 times in infarcted patients with cardiorenal syndrome that presented metabolic syndrome, left ventricular dysfunction and reduced glomerular filtration rate.
The factors obtained using the logistic regression model constitute an useful tool to assess the influence of cardiorenal syndrome on mortality due to acute myocardial infarction.
REFERENCES
Núñez J, Miñana G, Santas E, Bertomeu González V. Síndrome cardiorrenal en la insuficiencia cardiaca aguda: revisando paradigmas. Rev Española Cardiol. 2015[citado 15/08/2021];68(5): 426-435. Disponible en: https://www.revespcardiol.org/es-sindrome-cardiorrenal-insuficiencia-cardiaca-aguda-articulo-S0300893215000123
Ronco C, Peter McCullough P, Anker SD, Anand I, Aspromonte N, Bagshaw SM,et al. Cardio-renal syndromes: report from the consensus conference of the Acute Dialysis Quality Initiative. Eur Heart J. 2010[citado 15/08/2021]; 31(6): 703-711. Disponible en: https://academic.oup.com/eurheartj/article/31/6/703/419179
Rodríguez Jiménez AE, Negrín Valdés T, Cruz Inerarity H, Machural de la Torre PJ. Síndrome cardiorrenal como predictor de mortalidad intrahospitalaria en el síndrome coronario agudo con elevación del segmento ST. Clín e Investig Arteriosclerosis. 2018[citado 15/08/2021];30(4):163-169. Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S0214916818300056?via%3Dihub
Montero Pérez Barquero M, Morales Rull JL. Posibilidades de órgano protección en la insuficiencia cardiaca aguda. Rev Clín Esp(Barc). 2016[citado 25/07/2020];216(3): 157-164.Disponible en: https://www.revclinesp.es/es-posibilidades-organoproteccion-insuficiencia-cardiaca-aguda-articulo-S0014256516000060
Manzur Barbur MC, Mejía-Sanjuanelo AM, Anaya-Taboada M, García-Domínguez JC, Molano- Triviño A. Estado del arte del síndrome cardiorrenal, ventajas y limitaciones de las terapias conocidas. Rev Colomb Nefrol. 2021 [citado 04/10/2021];8(2):e517. Disponible en: https://revistanefrologia.org/index.php/rcn/article/view/517
Cuevas Campillo A. Factores de riesgo para la presentación del síndrome cardiorrenal tipo I en pacientes con diagnóstico de insuficiencia cardiaca crónica descompensada en el servicio de medicina interna del hospital general de atizapan en el periodo de marzo 2013 a octubre 2016. [Tesis].[Toluca, Estado de México]: Hospital General de Atizapan “Dr. Salvador González Herrejón”;2017.93 p. Disponible en: http://ri.uaemex.mx/bitstream/handle/20.500.11799/65485/8%20Tesis%20Axel%20Cuevas%20Campillo%20Cuenta%20MEDICINA%20INTE..pdf?sequence=1&isAllowed=y
Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive Summary of The Third Report of The National Cholesterol Education Program (NCEP) Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel III). JAMA. 2001[citado 280/08/2020];285(19):2486-2497.Disponible en: https://jamanetwork.com/journals/jama/article-abstract/193847
Jacobson T, Ito M , Maki K, Orringer C ,Bays H,Jones P, et al. National lipid association recommendations for patient-centered management of dyslipidemia: part 1--full report. J Clin Lipidol. 2015[citado 27/01/2021];9(2):129-169:Disponible en: https://www.sciencedirect.com/science/article/abs/pii/S1933287415000598
De Melo Leite A, Ferraz de Oliveira Gomes B, Casarsa Marques A, Fernandes Petriz JL, Campos de Albuquerque D, Pimenta de Mello Spineti P, et al. Acute Cardiorenal Syndrome: Which Diagnostic Criterion to Use And What is its Importance for Prognosis?. Arq Bras Cardiol. 2020[citado 25/01/2020];115(1): 127-133.Disponible en: http://publicacoes.cardiol.br/portal/abc/ingles/2020/v11501/pdf/i11501022.pdf
Avila Rodriguez LV, Montero O, Toro J, Mondragon Cardona Á, Jiménez Canizales CE. Prevalencia de síndrome cardiorrenal en un hospital de referencia del suroriente colombiano, 2013-2015. Acta Méd Colomb. 2016[citado 25/08/2021];41 (3 Supl 1): 95. Disponible en: https://go.gale.com/ps/anonymous?id=GALE%7CA472372538&sid=googleScholar&v=2.1&it=r&linkaccess=abs&issn=01202448&p=IFME&sw=w
Huaman Mejía YD. Injuria renal aguda como factor asociado a mortalidad en pacientes con síndrome isquémico coronario agudo del servicio de medicina especialidades del Hospital III José Cayetano Heredia ESSALUD Piura. 2014-2017[Tesis].[ Piura,Peru]:Universidad Privada Antenor Orrego; 2018. 47p.Disponible en: https://repositorio.upao.edu.pe/bitstream/20.500.12759/4028/1/REP_MED.HUMA_YENIFFER.HUAMAN_INJURIA.RENAL.AGUDA.FACTOR.ASOCIADO.MORTALIDAD.PACIENTES.S%c3%8dNDROME.ISQU%c3%89MICO.CORONARIO.AGUDO.SERIVICIO.MEDICINA.ESPECIALIDADES.HOSPITAL.III.JOS%c3%89.CAYETANO.HEREDIA.ESSALUD.PIURA.2014.2017.pdf
Yancy C, Lopatin M, Warner Stevenson L, De Marco T, Fonarow G, ADHERE Scientific Advisory Committee and Investigators. Clinical Presentation, Management, and In-Hospital Outcomes of Patients Admitted With Acute Decompensated Heart Failure With Preserved Systolic Function A Report From the Acute Decompensated Heart Failure National Registry (ADHERE) Database. J Am Coll Cardiol. 2006[citado 25/04/2020];47(1):76-84.Disponible en: https://www.jacc.org/doi/full/10.1016/j.jacc.2005.09.022
Madeira M, Caetano F, Almeida I, Fernández A, Reis L, Costa M, et al. Inotropes and cardiorenal syndrome in acute heart failure. A retrospective comparative analysis. Rev Port Cardiol. 2017[citado 15/07/2020];36(9):619-625.Disponible en: https://www.sciencedirect.com/science/article/pii/S2174204917302404
Meza Ayala CM, Dehesa López EE. Factores asociados con lesión renal aguda en pacientes hospitalizados con diagnóstico de insuficiencia cardíaca agudizada. Med Interna Méx.2018[citado 28/07/2020];34(1):19-28.Disponible en: http://www.scielo.org.mx/scielo.php?script=sci_arttext&pid=S0186-48662018000100004
Bono J, Perna ER, Macín Stella M. Fallo renal e infarto de miocardio ¿un marcador pronóstico? Registro argentino de infarto agudo de miocardio SAC-FAC. Rev Fed Arg Cardiol. 2018[citado 15/08/2021]; 47(2):91-96. Disponible en:https://docplayer.es/116154502-Fallo-renal-e-infarto-agudo-de-miocardio-un-marcador-pronostico-registro-argentino-de-infarto-agudo-de-miocardio-sac-fac.html