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2023, Number 5

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Med Crit 2023; 37 (5)

Thrombocytosis in the burned patient

Garnica EMA, Herrera IJE, Jimeno PRG, Urueña MTP, Serviño GNF, Carrillo ADI, Torres SD

Language: Spanish
References: 16
Page: 429-433
PDF size: 242.17 Kb.


ABSTRACT

The microcirculatory dysfunction of the tissues after a burn generates ischemia and hypoxia of tissues and organs, weakening the course of tissue repair, as well as the generation of various complications during the resuscitation of the burned patient. The platelet is an important component of the blood and during a burn it undergoes alterations in its rheological behavior that, ultimately, can favor the appearance and development of microcirculatory dysfunction. These alterations can be explained by changes in platelet morphology, in their mechanisms of activation, adhesion, and aggregation, while the immunological functions of platelets seem to have a direct influence on the prognosis of the disease, infection rates, and time of infection. Recovery. The understanding of these phenomena can be very useful by generating a direct impact on the course of evolution and helping treatment. In this review, platelet alterations are analyzed with special attention to thrombocytosis and its possible repercussions during the resuscitation and treatment of the burned patient.


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