2021, Number 4
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Rev cubana med 2021; 60 (4)
Glioblastoma multiforme with pseudovascular presentation
Cansino CLA, Morales BI, Roiz BMM
Language: Spanish
References: 10
Page: 1-9
PDF size: 314.18 Kb.
ABSTRACT
Introduction: Glioblastoma multiforme is the most frequent and aggressive
primary brain tumor in adults, representing about 25% of intracranial tumors. The
main clinical manifestations are given by headache, seizures, behavior changes and a more defined focal syndrome (frontal, temporal, parieto-occipital or corpus
callosum). In some patients, the onset is abrupt due to bleeding or rapid growth
of an intratumoral cyst. The diagnosis is made by magnetic resonance imaging and
confirmed with brain biopsy. Treatment is multidisciplinary and it includes
surgical resection, chemotherapy, and radiation therapy. However, the prognosis
is poor in most patients.
Objective: To describe the case of a patient with glioblastoma multiforme that
presented in a pseudovascular form.
Clinical report: The case of a 60-year-old male patient with a history of arterial
hypertension and cerebrovascular disease is report. Three days before his
admission, he began to show difficulty speaking and gait disturbance due to loss
of muscle strength in the right half of his body. For the foregoing, he was taken to
Julio Trigo López Surgical Clinical Hospital where he was admitted and diagnosed
with a brain tumor. The patient evolved torpidly and died. The pathological study
revealed the presence of a glioblastoma multiforme.
Conclusions: The reported case of glioblastoma multiforme in the form of a motor
defect provides information on this condition that is not common in our center.
REFERENCES
Alegría Loyola MA, Galnares JA, Mercadoa M. Tumores del sistema nerviosocentral. Rev Med Inst Mex Seguro Soc. 2017[acceso: 10/09/2020];55(3):330-40.Disponible en: https://www.medigraphic.com/pdfs/imss/im-2017/im173i.pdf
ABTA. Glioblastoma y astrocitoma malign. Chicago: American Brain TumorAssociation c. 2012[acceso: 10/09/2020]. Disponible en:https://www.abta.org/wp-content/uploads/2018/03/glioblastoma-y-astrocitomamaligno.pdf
Piña Batista KM. Implicaciones pronósticas de la relación subventricular en elglioblastoma multiforme: caracterización clínica radiológica y patológica [tesisdoctoral]. Universidad de Oviedo; 2015. Disponible en:https://www.researchgate.net/publication/323388467
Bruna J, Graus F, Fernández-Vega I, Mateos B, Zarranz JJ. Neurooncología.Tumores cerebrales. En: Zarranz JJ. Neurología. 6ta. ed. Barcelona: Elsevier.2018[acceso: 12/09/2020]:519-52. Disponible en: https://booksmedicos,org
Sierra Benítez EM, León Pérez M, Hernández Román G. Comportamiento de losgliomas de alto grado en el servicio Neurocirugía de Matanzas. 2017-2019. RevMédica Electrónica. 2019[acceso: 12/09/2020];41(5). Disponible en:http://www.revmedicaelectronica.sld.cu/index.php/rme/article/view/3196
Sinning M. Clasificación de los tumores cerebrales. Rev Med Clin Condes.2017[acceso: 08/09/2020];28(3):339-42. Disponible en:https://www.elsevier.es/es-revista-revista-medica-clinica-las-condes-202-articulo-clasificacion-de-los-tumores-cerebrales-S0716864017300597
Gómez Vega JC, Ocampo Navia MI, Feo Lee O. Epidemiología y caracterizacióngeneral de los tumores cerebrales primarios en el adulto. Rev Univ Med.2019[acceso: 31/08/2020];60(1). Disponible en:https://revistas.javeriana.edu.co/files-articulos/UMED/60-1%20(2019-I)/231057460010/#fn1
Pérez Segura P. Tumores Cerebrales. Sociedad Española de Oncología Médica.2019[acceso: 10/09/2020]. Disponible: https://seom.org/info-sobre-elcancer/tumores-cerebrales?showall=1
Contreras LE. Epidemiología de tumores cerebrales. Rev Med Clin Condes.2017[acceso: 08/09/2020];28(3):332-38. Disponible en:https://www.elsevier.es/es-revista-revista-medica-clinica-las-condes-202-articulo-epidemiologa-de-tumores-cerebrales-S0716864017300585
Díaz Ojeda JL, Reyes Tápanes MC, Rodríguez Sánchez L, Sierra Benítez EM.Medios diagnósticos y tratamientos actuales del glioblastoma multiforme. RevProgal. 2020[acceso: 13/09/2020];3(2). Disponible en:http://www.revprogaleno.sld.cu/index.php/progaleno/article/view/165/70