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Órgano oficial de la Universidad Autónoma de Sinaloa

2023, Number 1

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Rev Med UAS 2023; 13 (1)

Association between Vitamin D Levels and Severe Pre-Eclampsia in Patients with a Single Term Pregnancy

Carvajal-Sepúlveda AR, Morgan-Ruiz FV, Gutiérrez-Arzapalo PY, Quevedo-Castro E, López-Manjarrez G, Beltrán-Ontiveros SA, Báez-Barraza J, Morgan-Ortiz F

Language: Spanish
References: 19
Page: 45-54
PDF size: 196.22 Kb.


ABSTRACT

Objective: To determine the frequency of hypovitaminosis D in patients with preeclampsia with data on severity and term pregnancy with a single live product. Material and methods: This is a case-control study, with the taxonomy of being a prospective, cross-sectional, observational and analytical study. “Cases” were described as: patients with severe preeclampsia and “control” was defined as: normotensive patients, without additional comorbidities, and singleton pregnancy. A sample of 60 patients with 30 patients per group is estimated, with a 95% confidence interval to estimate the frequency of hypovitaminosis D in severe preeclampsia. Fisher's exact test was used. The frequency is calculated as the number of cases with hypovitaminosis D among the total number of patients in the study. Results: The 25-hydroxyvitamin D serological status of both groups was analyzed; It was possible to demonstrate a vitamin D value of 24 ng/ml (SD: 6,214) in the control group, and a value of 21.5 ng/ml (SD: 6,731) in the case group. A total of 27 patients with hypovitaminosis status were presented in the case group (12 with insufficiency status and 15 with deficiency), and 25 patients with hypovitaminosis in the control group (17 with insufficiency status and 8 with deficiency), concluding that there are no significant differences in vitamin D deficiency (p value =0.153) Conclusions: No association was found between vitam,in D levels and preeclampsia .


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