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Colegio de Medicina Interna de México.

2023, Number 2

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Med Int Mex 2023; 39 (2)

Trauma-associated coagulopathy

Mercado-Avendaño G, Saavedra-Valencia ME, Herrera-Almanza L, Carvajal-Alzate M, Vergara-Yánez D, Cuartas-Agudelo YS, Martínez-Sánchez LM

Language: Spanish
References: 65
Page: 273-287
PDF size: 269.80 Kb.


ABSTRACT

Blood homeostasis can be altered by multiple factors. One of them is trauma, which usually occurs with hemorrhage generating alterations in the coagulation system. When this occurs, it is called trauma-induced coagulopathy. This disease encompasses disseminated intravascular coagulation, for which various factors that increase the risk of suffering from it have been described and various diagnostic scales have been developed. The objective of this review was to gather updated information on disseminated intravascular coagulation in trauma patients, risk factors, pathophysiology, diagnosis, and the use of thromboelastography in this clinical setting to provide key aspects in the adequate care of trauma patients, such as the timely detection of risk of coagulopathy through clinical criteria and the requirement of massive transfusion, which, when properly implemented, reduces the mortality of these patients. A scientific literature search was carried out during January 2021 in the Scielo, PubMed and ScienceDirect databases using the following MeSH descriptors: trauma, disseminated intravascular coagulation, diagnosis, treatment and thromboelastography; 1943 articles were located, of which those that were more up-to-date, exposing the pathophysiology of disseminated intravascular coagulation, the diagnostic criteria, treatment, or the use and advantages of thromboelastography were accepted, rejecting 1886 and selecting 57 articles for writing. Coming up next, a review about the relevant and updated aspects of trauma-induced coagulopathy, in order to bring the reader closer to the use of thromboelastography.


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