2023, Number 1
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Rev Latin Infect Pediatr 2023; 36 (1)
Carbapenem-resistant Acinetobacter baumannii in pediatric population: epidemiological overview
Castillo BJI, Casillas VN, Llaca DJ, Mascareñas SA
Language: Spanish
References: 41
Page: 42-46
PDF size: 187.38 Kb.
ABSTRACT
Acinetobacter baumannii has emerged as a threat to humanity due to the high prevalence of multidrug-resistant strains. This pathogen intrinsically produces β-lactamases, which confer resistance to some cephalosporins and can acquire novel resistance genes for carbapenemics. In addition to the blaOXA-
51 family present in A. baumannii, six enzyme subgroups have been reported in Latin America and the Caribbean. Currently, there are regional variations in the distribution of the molecular characteristics of these enzymes. The article reviews the literature with emphasis on the molecular epidemiology of carbapenem resistance in this microorganism.
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