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2022, Number 3

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Rev Hematol Mex 2022; 23 (3)

Effects and treatment of pernicious anemia in the health of the elderly

Cardoso-Reyes MC, Morales-Castillejos L

Language: Spanish
References: 33
Page: 146-158
PDF size: 300.99 Kb.


ABSTRACT

Objective: To determine the effects of pernicious anemia in elderly.
Methodology: A systematic search of original articles was carried out according to the indications proposed in the PRISMA guide (Preferred Reporting Items for Systematic reviews and Meta-Analyses); the databases consulted were PubMed, MedicLatina, Nutrition Reference Center, Sage Journals, Apa PsycNet, Eric and Food Science Source, with the Boolean AND and OR computers, under the keywords Pernicious anemia, Effects, Treatment and Older adults, based on MeSH (Medical Subject Heading) and DeCS (Descriptors of Health Sciences). The searches were in Spanish and English, during May and June 2021.
Results: Four hundred fifty-eight items were found, 379 of these were removed due to non-inclusion criteria, inconsistencies, articles not available in full text and other reasons (invalid instruments); 30 items were included and analyzed in this study. The effects of pernicious anemia in older adults found in these studies were: mild cognitive deficit and dementia syndrome, depression, neoplastic complications, myelophthisic anemia and venous thromboembolism.
Conclusions: According to the review of the studies, various factors are highlighted that are involved in affecting the performance of older adults, especially when they are associated with cognitive deficiency that result in significant disability and as well as loss in the quality of life.


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