2022, Número 3
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Rev Hematol Mex 2022; 23 (3)
Análisis de la incidencia del linfoma difuso de células B grandes y el linfoma folicular en tres países de América Central y el Caribe (República Dominicana, Guatemala y Panamá)
Álvarez-Alvarado AM, López-Barquero A, Buitrón N, Quiel D, Cumba T, Matos C, Vasallo R, Torselli S
Idioma: Español
Referencias bibliográficas: 34
Paginas: 131-141
Archivo PDF: 253.95 Kb.
RESUMEN
Objetivo: Determinar la incidencia y la recaída o resistencia de dos tipos de linfoma
no Hodgkin (linfoma difuso de células B grandes y linfoma folicular) en República
Dominicana, Guatemala y Panamá entre 2014 y 2018.
Materiales y Métodos: Estudio retrospectivo, observacional, multicéntrico, de
cohortes, efectuado en pacientes mayores de 18 años con diagnóstico de linfoma no
Hodgkin. Se recolectaron retrospectivamente datos demográficos y clínicos.
Resultados: Se incluyeron 443 pacientes con linfoma no Hodgkin. La edad media al
diagnóstico fue de 56.2 ± 16.9 años, el 54% eran varones. La tasa bruta de incidencia
global del linfoma no Hodgkin por país y tipo fue de 5.9 por cada 100,000 personas
en Panamá, 1.4/100,000 personas en República Dominicana y 0.4/100,000 personas
en Guatemala. La estimación de la tasa bruta de incidencia del linfoma no Hodgkin
por países se mantuvo estable en el periodo analizado.
Conclusiones: La población con linfoma no Hodgkin de Centroamérica y el Caribe
muestra características similares a las mundiales. La elección del tratamiento de linfoma
difuso de células B grandes y linfoma folicular corresponde a las recomendaciones de
las principales guías clínicas internacionales. La incidencia del linfoma no Hodgkin
es menor en Centroamérica y el Caribe que en otras regiones del mundo, pero la edad
al momento del diagnóstico es 10 años menor.
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