Hernández MVJ, Díaz SAM, Gómez HT, Bécquer ML, Rodríguez VCM, Herrera MM

Language: Spanish
References: 20
Page: 590-605
PDF size: 965.56 Kb.

ABSTRACT

Introduction: the typical lesion caused by Staphylococcus aureus is the furuncle or any other localized abscess.
Objective: to describe the manifestation of the proteinogram and serum immunoglobulin levels.
Methods: a prospective longitudinal study was carried out in 70 patients with furuncles infected by Staphylococcus aureus, who came to the Immunology consultations from various locations of Villa Clara.
Results: protein fractions were determined by elution method; serum immunoglobulins were quantified according to age, gender and skin color of the patients by simple radial immunodiffusion. Variables were contrasted under the Chi-square test, with 95% confidence significance. White patients predominated over non-white ones. Normal results were obtained for total proteins and gamma fraction in protein electrophoresis. Low values were obtained for albumin, alpha 1, alpha 2 and beta globulin fraction, above 95% valid.
Conclusions: all immunoglobulins were normal or high, according to the reference intervals for each age group. The result obtained in the correlation between IgA and the beta fraction was striking when correlating the immunoglobulin values with the electrophoresis fractions. In general, the antibodies did not show significant variations in their correlations, which evidenced a poor role in infection. We concluded that alpha 1, alpha 2 and beta globulin values may be important in the disease.

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