2023, Number 2
<< Back Next >>
Med Int Mex 2023; 39 (2)
Myelopathy secondary to systemic lupus erythematosus
Vicente-Altabás MA, Capablo-Liesa JL, Velilla-Marco J, Vicente-Altabás MJ
Language: Spanish
References: 7
Page: 412-417
PDF size: 224.32 Kb.
ABSTRACT
Background: The neurological involvement of systemic lupus erythematosus
encompasses 19 clinical syndromes, within which acute myelitis is one of the most
infrequent (1-2%). The diagnosis is complex since it is necessary to determine if the
manifestation is due to the activity of systemic lupus erythematosus or is a consequence
of infections, adverse reactions to treatments or other systemic diseases. High
clinical suspicion and early treatment is essential since the delay in it can lead to
irreversible consequences.
Clinical case: A 41-year-old female patient, with a previous diagnosis of systemic
lupus erythematosus, and 3 years later, manifested myelopathy.
Conclusions: This case illustrates the diagnostic difficulty of neurological involvement
of systemic lupus erythematosus and the associated morbidity and mortality that
entails.
REFERENCES
Kivity S, Agmon-Levin N, Zandman-Goddard G, Chapman J.Neuropsychiatric lupus: a mosaic of clinical presentations.BMC Medicine 2015; 13: 43. doi: 10.1186/s12916-015-0269-8.
Gil AR, Solís CU, Milera RJ, de Armas HA. Transverse myelitisas premiere of a systemic lupus erythematous. Rev CubanaReumatología 2013; 3: 209-213.
Schulz W, Shenin M, Mehta A, Kebede A, Fluerant M. Initialpresentation of acute transverse myelitis in systemic lupuserythematosus: Demographics, diagnosis, managementand comparison to idiopathic cases. Rheumatol Int. 2012;32(9):2623-78.
Díaz D, Correa N, Díaz MC, Gutiérrez JM, et al. Compromisodel sistema nervioso central en el lupus eritematoso sistémico.Rev Colom Reumatol 2015; 22 (1): 16-30. https://doi.org/10.1016/j.rcreu.2015.02.001.
Chiganer E, Hryb J, Contentti E. Mielitis y lupus: clínica, diagnósticoy tratamiento. Revisión. Reumatol Clin 2017; 13 (6):344-348. https://doi.org/10.1016/j.reuma.2016.06.004.
Díaz-Lagares C, Brito-Zerón P. Recomendaciones sobre eluso de Belimumab en lupus eritematoso sistémico. Guíade práctica clínica SEMI 2012.
Hermosillo-Romo D, Brey LR. Diagnosis and managementof patients with neuropsychiatric systemic lupus erythematosus(NPSLE). Best Pract Res Clin Rheumatol 2002; 16(2): 229-44. doi: 10.1053/berh.2001.0223.