2023, Number 1
<< Back Next >>
Med Int Mex 2023; 39 (1)
Systemic high blood pressure in the geriatric patient
Arellano-Navarro CE, Pérez-García CC, Martínez-Gallardo L, León ÁKG, Arriaga-García RJP
Language: Spanish
References: 25
Page: 91-98
PDF size: 228.09 Kb.
ABSTRACT
Cardiovascular diseases are the leading cause of death worldwide. Systemic arterial
hypertension is directly related to half of deaths from cardiovascular complications.
The pathophysiology of hypertension is special in the elderly, which added to the
multiple comorbidities and geriatric syndromes of each individual, makes the diagnosis
and treatment of this disease complex and difficult to generalize. This complexity is
reflected in the controversy in the literature regarding blood pressure levels that are
adequate for an older adult. The purpose of this review is to facilitate the physician
decision-making process in the diagnosis, the optimal goals of control for the robust
and frail patient, and the selection of pharmacological and non-pharmacological treatment,
through a critical analysis that comprises available evidence in the literature
that includes geriatric population, such as the Sprint senior study, the Hyvet study, the
ESC/ESH 2018 Guide on the diagnosis and treatment of arterial hypertension and the
Guide for prevention, detection, evaluation and management of arterial hypertension
of the American College of Cardiology. Strict blood pressure control reduces some
cardiovascular complications in geriatric patients; however, it can be associated with
cognitive impairment and kidney injury, which results in a decline in patient’s functionality
and quality of life. Therefore, it is important that our first goal in treatment is
to avoid adverse effects: first do no harm.
REFERENCES
Organización Mundial de la Salud. (2019, 13 septiembre).Hipertensión. Recuperado de https://www.who.int/es/news-room/fact-sheets/detail/hypertension
World Health Organization. (2013). A global brief on Hypertension.Silent killer, global public health crisis. WHO,I(IV). Recuperado de https://apps.who.int/iris/bitstream/handle/10665/79059/WHO_DCO_WHD_2013.2_eng.pdf;jsessionid=4BF33153B42C8EA34C43182775DD30A5?sequence=1
Mendoza-Núñez, Víctor M. (2018). Envejecimiento y vejez.Recuperado de http://inger.gob.mx/pluginfile.php/mod_resource/content/5/Repositorio_Cursos/Archivos/Promocion/Unidad_I/PSM_Lectura_Envejecimiento_y_vejez.pdf
Instituto Nacional de Salud Pública. (2016). EncuestaNacional de Salud y Nutrición de Medio Camino 2016(ENSANUT MC 2016). Informe final de resultados. Recuperadode https://www.gob.mx/cms/uploads/attachment/file/209093/ENSANUT.pdf
Machado L, Rey-Lopez JP, Rodrigues-Matsudo VK, Do CarmoO. Sedentary behavior and health outcomes amongolder adults: a systematic review. BMC Public Health 2014;14: 333. doi: 10.1186/1471-2458-14-333.
Appel L, Espeland M, Easter L, Wilson AC, et al. Effects ofreduced sodium intake on hypertension control in olderindividuals. results from the Trial of NonpharmacologicInterventions in the Elderly (TONE). Arch Intern Med 2001;161 (5): 685-693. doi: 10.1001/archinte.161.5.685.
Osher E, Stern N. Obesity in elderly subjects. Am DiabetesAssoc Diab Care 2009; 32(2): 398-402. doi: 10.2337/dc09-S347.
Unger T, Borghi C, Charchar F, Khan NA, et al. 2020 InternationalSociety of Hypertension global hypertension practiceguidelines. J Hypertension 2020; 38 (6): 982-1004. https://doi.org/10.1161/HYPERTENSIONAHA.120.15026.
Mikael LR, Machado A, Mota M, Lima A, et al. Vascularaging and arterial stiffness. Arq Bras Cardiol 2017; 109:253-258. doi: 10.5935/abc.20170091.
Oparil S, Acelajado MC, Bakris GL, Berlowitz D, et al. Hypertension.Nat Rev Dis Prim 2018; 4: 18014. doi: 10.1038/nrdp.2018.14.
Sander GE. Hypertension in the elderly. Curr HypertensRep 2004; 6: 469-476.
Sulakova T, Feber J, Strnadel J, Pavlicek J, et al. The importanceof pulse wave velocity measurement in geriatricpopulation with an increased risk of cardiovascular diseases– Type 1 diabetes and chronic kidney disease. Cor etVasa 2016; 58 (6): e623-e630. https://doi.org/10.1016/j.crvasa.2016.03.007.
Beckett NS, Peters R, Fletcher AE, Staessen JA, et al.Treatment of hypertension in patients 80 years of age orolder. N Engl J Med 2008; 358: 1887-1898. DOI: 10.1056/NEJMoa0801369.
Williamson JD, Supiano MA, Applegate WB, Berlowitz DR,et al. Intensive vs standard blood pressure control and cardiovasculardisease outcomes in adults aged ≥75 years: Arandomized clinical trial. JAMA 2016; 315 (24): 2673-2682.https://doi.org/10.1001/jama.2016.7050.
Williamson J. Effect of intensive vs standard bloodpressure control on probable dementia: a randomizedclinical trial. JAMA 2019; 321 (6): 553-561. doi:10.1001/jama.2018.21442.
Walker KA, Sharrett AR, Wu A, Schneider A, et al. Associationof midlife to late-life blood pressure patterns withincident dementia. JAMA 2019; 322 (6): 535-545. doi.org/10.1001/jama.2019.10575.
The SPRINT research group. A randomized trial of intensiveversus standard blood-pressure control. N Engl J Med 2015;373: 2103-2116. DOI: 10.1056/NEJMoa1511939.
Grupo de Trabajo de la Sociedad Europea de Cardiología(ESC) y la European Society of Hypertension (ESH) sobreel diagnóstico y tratamiento de la hipertensión arterial.Guía ESC/ESH 2018 sobre el diagnóstico y tratamientode la hipertensión arterial. Rev Esp Cardiol 2019; 72 (2):160.e1-e78. https://doi.org/10.1016/j.recesp.10.1016/j.recesp.2018.11.022.
Whelton PK, Carey RM, Aronow WS, Casey D, et al. 2017ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the Prevention, Detection, Evaluation,and Management of High Blood Pressure in Adults:Executive Summary: A Report of the American Collegeof Cardiology/American Heart Association Task Force onClinical Practice Guidelines. Hypertension 2018; 71 (6):1269-1324. doi: 10.1161/HYP.0000000000000066.
Gil G, et al. Guía de buena práctica clínica en geriatría:Hipertensión en el anciano. IMC 2012. Expert ConsensusDocument on Hypertension in the Elderly. American Collegeof Cardiology Foundation.
López MR, López TJ. Tratamiento no farmacológico de lahipertensión arterial en el anciano. En: Gil GP. Guía debuena práctica clínica en geriatría. Hipertension en elAnciano. Madrid: IMC; 2012: 29-42.
Sander GE. Drugs that increase blood pressure. Therapy2011.
Corrao G, Mazzola P, Monzio CM, Rea F, et al. Antihypertensivemedications, loop diuretics, and risk of hip fracture inthe elderly: a population-based cohort study of 81,617 Italianpatients newly treated between 2005 and 2009. DrugsAging 2015; 32: 927-936. doi: 10.1007/s40266-015-0306-5.
Kjeldsen SE, Stenehjem A, Os I, Van de Borne P, et al.Treatment of high blood pressure in elderly and octogenarians:European Society of Hypertension statement onblood pressure targets. Blood Press 2016; 25: 333-336. doi:10.1080/08037051.2016.1236329.
Filella AD. Tratamiento farmacológico de la hipertensiónarterial en el anciano. En: Gil GP. Guía de buena prácticaclínica en geriatría. Hipertension en el Anciano. Madrid:IMC; 2012: 43-54.