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2022, Number 4

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Rev Nefrol Dial Traspl 2022; 42 (4)

Impact of coronavirus infection on anxiety and quality of life in individuals with a kidney transplant

Faraldo-Cabana A, Gimeno HV, Peix JMB, Fernández CAM, Asensio AS, Beneit MJV, Zaragoza-García I, Sánchez FA, Ortuño-Soriano I

Language: English
References: 46
Page: 264-264
PDF size: 205.45 Kb.


ABSTRACT

Background: The consequences of SARSCoV- 2 infection on the mental health of kidney transplant recipients have not yet been investigated. Objectives: This study compares anxiety and quality of life in individuals with a kidney transplant who did or did not test positive for coronavirus. Design: Retrospective study of two prospective cohorts. Participants: Kidney transplant recipients under follow-up in a Spanish tertiary teaching hospital who tested positive for coronavirus (cases); and consecutive kidney recipients who had not suffered the infection (not-cases). Methods: Mortality and case fatality data were compared between the two cohorts for the two pandemic waves. For the second wave (July 1 to December 5, 2020), the data compared between cases (n=22) and not-cases (n=36) were state and trait anxiety (STAI), kidney transplant-related quality of life (KTQ), and mortality as the main outcome variables. Results: 601 transplanted persons of mean age 61.7 years (SD 12.8), 61.9% men. 12.1% (n=73) tested SARS-CoV-2-positive over the first two pandemic waves with a mortality of 2.9% and case fatality of 24.7%. Over the second wave, the mean quality of life score was 4.1 (SD 0.9) and the overall anxiety score was 49 (SD 24.3) for the two cohorts, which did not vary in terms of the impacts of these measures on the descriptive variables examined. Conclusions: Quality of life is invariably affected, and levels of anxiety are high regardless of whether or not they have had a SARS-CoV-2 infection. Over the period examined, mortality was low while coronavirus case fatality was high.


REFERENCES

  1. Faraldo Cabana A, Ibáñez Rebé M, Del Río RodríguezM, Esteban Polonio C, Lope Andrea T, MuñozJiménez DM. Frequency of nursing diagnoses onthe first admission of the patient with a recent renaltransplant. Enferm Nefrol. 2017;20(1): 76–81.

  2. CKD Group. Kidney Disease: Improving GlobalOutcomes (KDIGO). Kidney int. 2012;3(2013): 1–150.

  3. Force A, Berlango J. Indicaciones del trasplante renal.Preparación preoperatoria. In: Panamericana, editor. Laenfermería y el trasplante de órganos. Madrid; 2004. p. 89.

  4. El said SH. Lifestyle Modification among PostRenal Transplant Recipient. IOSR J Nurs Heal Sci.2017;06(03): 92–113.

  5. Pascazio L, Nardone IB, Clarici A, Enzmann G,Grignetti M, Panzetta GO, et al. Anxiety, depressionand emotional profile in renal transplant recipientsand healthy subjects: A comparative study. TransplantProc [Internet]. 2010;42(9): 3586–90. Available from:http://dx.doi.org/10.1016/j.transproceed.2010.08.056.

  6. De Pasquale C, Veroux M, Indelicato L, Sinagra N,Giaquinta A, Fornaro M, et al. Psychopathologicalaspects of kidney transplantation: Efficacy of amultidisciplinary team. World J Transpl. 2014;4(4):267–75.

  7. Moreno Rubio F, Mora Villarroel SL, CastelblancoToro C, Molina López C, Ortiz Varela LA. Trastornoemocional en el paciente renal trasplantado. EnfermNefrol. 2016; 19: 147–53.

  8. Mendoza Lipa JR. Estrategias de afrontamiento ycalidad de vida en pacientes con trasplante renal delPrograma Nacional de Salud Renal La Paz-Bolivia[Tesis doctoral]. La Paz-Bolivia: Repositorio InstitucionalUniversidad Mayor de San Andrés; 2017.

  9. McClellan WM, Anson CA, Birkeli K, Tuttle E.Functional status, and quality of life: predictors ofearly mortality among patients entering treatment forend stage renal disease. J Clin Epidemiol. 1991;44(1):83–9.

  10. Barros-Higgins L, Herazo-Beltrán Y, Aroca-MartínezG. Health-related quality of life in patients with chronickidney disease. Rev Fac Med. 2015;63(4): 641–7.

  11. The WHOQOL G. The World Health Organizationquality of life assessment (WHOQOL): Positionpaper from the World Health Organization. SocSci Med [Internet]. 1995;41(10):1403–9. Availablefrom: https://www.sciencedirect.com/science/article/pii/027795369500112K.

  12. Fiebiger W, Mitterbauer C, Oberbauer R. Healthrelatedquality of life outcomes after kidneytransplantation. Health Qual Life Outcomes. 2004; 2:2.

  13. Sánchez JLC, Alonso RP, Rodríguez EI, Crespo AA,de Buruaga Perea AS, Elena Incera Setién M, et al.Factores sociológicos y calidad de vida relacionada conla salud en pacientes en hemodiálisis. Enferm Nefrol.2011;14(2): 98–104.

  14. Varela L, Vázquez MI, Bolanos L, Alonso R. Predictorespsicológicos de la calidad de vida relacionada con lasalud en pacientes en tratamiento de diálisis peritoneal.Nefrología [Internet]. 2011; 31: 97–106. Availablefrom: http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0211-69952011000100015&nrm=iso.

  15. Perales-Montilla C, Ana GL, Paso G. Psychosocialpredictors of the quality of life of chronic renal failurepatients undergoing haemodialysis. Nefrología. 2012;32: 622–30.

  16. WHO. Coronavirus disease 2019 (COVID-19).Situation report-85 [Internet]. 2020 [cited 2020Oct 25]. Available from: https://www.who.int/publications/m/item/situation-report---85.

  17. WHO. Director-General’s remarks at the mediabriefing on COVID-19 on 11 March 2020 [Internet].2020 [cited 2020 Oct 25]. Available from: https://www.who.int/dg/speeches/detail/who-director-general-sopening-remarks-at-the-media-briefing-on-covid-19---11-march-2020.

  18. Michaels MG, La Hoz RM, Danziger-Isakov L,Blumberg EA, Kumar D, Green M, et al. Coronavirusdisease 2019: Implications of emerging infections fortransplantation. Am J Transpl. 2020;20(7): 1768–72.

  19. Zhu L, Gong N, Liu B, Lu X, Chen D, Chen S,et al. Coronavirus Disease 2019 Pneumonia inImmunosuppressed Renal Transplant Recipients: ASummary of 10 Confirmed Cases in Wuhan, China.Eur Urol Suppl [Internet]. 2020;77(6): 748–54.Available from: https://pubmed.ncbi.nlm.nih.gov/32317180.

  20. Ahmadpoor P, Rostaing L. Why the immune systemfails to mount an adaptive immune response to aCOVID-19 infection. Transpl Int. 2020; 33: 824–5.

  21. Gobierno de España. Ministerio de Sanidad. Situacióny evolución de la pandemia de COVID-19 en España[Internet]. 2020 [cited 2020 Dec 25]. Available from:https://cnecovid.isciii.es/covid19#ccaa.

  22. Guillén-Riquelme A, Buela-Casal G. Psychometricrevision and differential item functioning in the StateTrait Anxiety Inventory (STAI). Psicothema [Internet].2011;23(3): 510–5. Available from: http://www.ncbi.nlm.nih.gov/pubmed/21774907.

  23. Paes de Barros B, Luiz Nishiura J, Pfeferman HeilbergI, Mastroianni Kirsztajn G. Ansiedade, depressão equalidade de vida em pacientes autossômica dominante.J Bras Nephrol. 2011;33(2): 120–8.

  24. Fonseca-Pedrero E, Paino M, Sierra-Baigrie S, Lemos-Giráldez S, Muñiz J. Propiedades Psicométricas del“Cuestionario de Ansiedad Estado-Rasgo” (STAI) enUniversitarios. Psicol Conduct. 2012;20(3): 547–61.

  25. Rebollo P, Ortega F, Ortega T, Valdés C, García-Mendoza M, Gómez E. Spanish validation of the“kidney transplant questionnaire”: a useful instrumentfor assessing health related quality of life in kidneytransplant patients. Health Qual Life Outcomes[Internet]. 2003; 1: 56. Available from: https://pubmed.ncbi.nlm.nih.gov/14613566.

  26. Tull MT, Edmonds KA, Scamaldo KM, RichmondJR, Rose JP, Gratz KL. Psychological OutcomesAssociated with Stay-at-Home Orders and the PerceivedImpact of COVID-19 on Daily Life. Psychiatry Res.2020; 289: 113098.

  27. Gobierno de España. Ministerio de Sanidad.Consejo Interterritorial Sistema Nacional de Salud.Instituto de Salud Carlos III. Estudio ENE-COVID:Informe final. Estudio nacional de sero-epidemiologíade la infección por SARS-CoV-2 en España. [Internet].2020 [cited 2021 May 9]. Available from: https://www.mscbs.gob.es/gabinetePrensa/notaPrensa/pdf/INFOR060720134446500.pdf

  28. Rodriguez-Cubillo B, de la Higuera MAM, LucenaR, Franci E V, Hurtado M, Romero NC, et al. Shouldcyclosporine be useful in renal transplant recipientsaffected by SARS-CoV-2? Am J Transpl. 2020;20(11):3173–81.

  29. Sánchez-Álvarez JE, Pérez Fontán M, Jiménez MartínC, Blasco Pelícano M, Cabezas Reina CJ, SevillanoPrieto ÁM, et al. SARS-CoV-2 infection in patients onrenal replacement therapy. Report of the COVID-19Registry of the Spanish Society of Nephrology (SEN)TT - Situación de la infección por SARS-CoV-2 enpacientes en tratamiento renal sustitutivo. Informedel Registro COV. Nefrología [Internet]. 2020;40(3):272–8. Available from: https://pubmed.ncbi.nlm.nih.gov/32389518.

  30. Cravedi P, Mothi SS, Azzi Y, Haverly M, FaroukSS, Pérez-Sáez MJ, et al. COVID-19 and kidneytransplantation: Results from the TANGOInternational Transplant Consortium. Am J Transpl.2020;20(11): 3140–8.

  31. Pascual J, Melilli E, Jiménez-Martín C, González-Monte E, Zárraga S, Gutiérrez-Dalmau A, et al.COVID-19-related Mortality During the First 60 DaysAfter Kidney Transplantation. Eur Urol [Internet].2020;78(4): 641–3. Available from: https://pubmed.ncbi.nlm.nih.gov/32624283.

  32. Akdur A, Karakaya E, Ayvazoglu Soy EH, AlshalabiO, Kirnap M, Arslan H, et al. Coronavirus Disease(COVID-19) in Kidney and Liver Transplant Patients:A Single-Center Experience. Exp Clin Transpl.2020;18(3): 270–4.

  33. Pérez-Laurrabaquio O. COVID-19 en España:primera ola de la emergencia. Med Gen Fam [Internet].2021; 10: 3–9. Available from: http://mgyf.org/covid-19-en-espana-primera-ola-de-la-emergencia/

  34. Ministerio de Sanidad. Secretaría General deSanidad. Dirección General de Salud PúblicaCalidad e Innovación. Centro de Coordinaciónde Alertas y Emergencias Sanitarias. Situación deCOVID-19 en España. Casos diagnosticados a partirdel 10 de mayo [Internet]. 2020 [cited 2021 May 8].Available from: https://www.isciii.es/QueHacemos/Ser vic ios/Vigi lanc iaSaludPbul icaRENAVE/Enf e rmed ade sTr a nsmi s i b l e s /Document s /INFORMES/Informes COVID-19/InformeCOVID-19. No 56_09 de diciembre de 2020.pdf

  35. Pérez-Sáez MJ, Blasco M, Redondo-Pachón D,Ventura-Aguiar P, Bada-Bosch T, Pérez-Flores I, et al.Use of tocilizumab in kidney transplant recipients withCOVID-19. Am J Transpl. 2020;20(11): 3182–90.

  36. Manterola C, Otzen T. Los sesgos en investigaciónclínica. Int J Morphol. 2015;33(3): 1156–64.

  37. Dweib K, Jumaa S, Khdour M, Hallak H. Qualityof life for kidney transplant palestinian patients.Saudi J Kidney Dis Transpl [Internet]. 2020;31(2):473–81. Available from: https://www.sjkdt.org/article.asp?issn=1319-2442

  38. Junchotikul P, Charoenthanakit C, Saiyud A,Parapiboon W, Ingsathit A, Jirasiritham S, et al.Assessment of the Changes in Health-related Qualityof Life After Kidney Transplantation in a Cohort of 232Thai Patients. Transplant Proc [Internet]. 2015;47(6):1732–5. Available from: https://www.sciencedirect.com/science/article/pii/S0041134515004741

  39. Mansouri P, Sayari R, Dehghani Z, Naimi Hosseini F.Comparison of the Effect of Multimedia and BookletMethods on Quality of Life of Kidney TransplantPatients: A Randomized Clinical Trial Study. Int JCommunity Based Nurs Midwifery. 2020;8(1): 12–22.

  40. Shrestha A, Shrestha A, Basarab-Horwath C, McKaneW, Shrestha B, Raftery A. Quality of life following livedonor renal transplantation: a single centre experience.Ann Transpl. 2010;15(2): 5–10.

  41. Salari N, Hosseinian-Far A, Jalali R, Vaisi-RayganiA, Rasoulpoor S, Mohammadi M, et al. Prevalence ofstress, anxiety, depression among the general populationduring the COVID-19 pandemic: a systematic reviewand meta-analysis. Glob Heal. 2020;16(1): 57.

  42. Pollice R, Di Mauro S, Bernardini M, Bianchini V,Giordani Paesani N, Ussorio D, et al. Psychopathology,quality of life and social functioning in dialysistreatment and kidney transplantation patients. ClinTer. 2010;161(4): 329–33.

  43. Vindegaard N, Benros ME. COVID-19 pandemicand mental health consequences: Systematic review ofthe current evidence. Brain Behav Immun. 2020; 89:531–42.

  44. Bigalke JA, Greenlund IM, Carter JR. Sex differencesin self-report anxiety and sleep quality duringCOVID-19 stay-at-home orders. Biol Sex Differ.2020;11(1): 56.

  45. Brooks SK, Webster RK, Smith LE, WoodlandL, Wessely S, Greenberg N, et al. The psychologicalimpact of quarantine and how to reduce it: rapid reviewof the evidence. Lancet [Internet]. 2020;395(10227):912–20. Available from: http://dx.doi.org/10.1016/S0140-6736(20)30460-8.

  46. Ozcan SG, Poyraz BC, Bakir A, Trabulus S, PekmezciS, Seyahi N. Coronavirus Pandemic: Mood Statuses ofRenal Transplant Recipients During Social Isolationand Lockdown Periods. Exp Clin Transpl [Internet].2021; Advance online publication. Available from:http://www.ectrx.org/detail/epub/1/1/1/0/1037/0.




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