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2023, Number S1

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Acta Med 2023; 21 (S1)

Portal hypertension

Ibarrola-Calleja JL, Núñez BF, Rodríguez GM, Ordóñez-Céspedes J

Language: Spanish
References: 105
Page: s57-65
PDF size: 209.49 Kb.


ABSTRACT

Portal hypertension (HP) is a complex handling pathological condition. It is among the ten more frequent causes of mortality in Mexico and is defined as the increase of the portal system (SP) pressure over 12 mmHg. The most frequent etiology is hepatic cirrhosis (CH), so the HP sinusoidal intrahepatic type has the higher incidence. The pathophysiology of the HP is produced by an increment of splachnic vascular resistance and blood volume, conditions that result in systemic alterations and vascular and microvascular modifications, secondary to hormonal, endothelial and neuronal products, leading to all the clinical manifestations. All of these factors should be taken into a count to decide the management and therapeutics for each patient, aspects that are mentioned in this review.


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